Jiang Hu,Guang-Rong Yang,Ren Ji et al.
Jiang Hu et al.
A phytochemical investigation on the 80% EtOH extract of the leaves of Paederia scandens (Lour.) Merr. resulted into the isolation of three undescribed iridoid glycosides, 10-O-trans-p-coumaroyl-(4R,6R)-3,4-dihydro-3α-methylthiopaederoside...
Design, synthesis and biological evaluation of aloperine derivatives as potential anticancer agents [0.03%]
异烟碱衍生物作为潜在抗肿瘤药物的设计、合成及生物活性评价研究
Tian-Tian Zhao,Long-Ying Shen,Yu Cheng et al.
Tian-Tian Zhao et al.
Modifications at different positions on the aloperine molecule were performed to improve its anticancer activity and develop anticancer drugs. The in vitro anticancer activities of 44 synthesized compounds were evaluated. The effect of modi...
Hong-Lian Chen,Jia-Ying Yao,Ming-Hui Gao et al.
Hong-Lian Chen et al.
Twelve compounds, comprising of four new ones, 6β,7α-limondiol (1) and ethyl 19-hydroxyisoobacunoate diosphenol (2), N-benzoyl 3-prenyltyramine (9) and 9-O-methyl integrifoliodiol (12), were isolated from the twigs with leaves of Tetradiu...
Hai-Chao Ge,Xiu-Hong Zhong
Hai-Chao Ge
Scutellarin, one of natural flavonoids from Scutellaria barbata D. Don and Erigeron breviscapus (vant) Hand.-Mazz. Modern pharmacological studies have shown that scutellarin has a good anti-tumor effect. According to the literature review a...
Natthaphitcha Khunsantiphong,May Thazin Thant,Chattarika Pengdee et al.
Natthaphitcha Khunsantiphong et al.
Dendroochreatene (1), a new phenanthrene derivative with a spirolactone ring, was isolated from the whole Dendrobium ochreatum plant together with 11 known compounds (2-12). The structure of the new compound was elucidated spectroscopically...
A new coumarin and a new flavonoid from Ochrocarpus longifolius [0.03%]
Ochrocarpus longifolius的新的香豆素和黄酮成分
Shu-Lan Liu,Feng Wei,Jin Li et al.
Shu-Lan Liu et al.
A new coumarin (1) and a new flavonoid (2) were isolated from the air-dried flower buds of Ochrocarpus longifolius, together with ten known compounds (3-12). The structures of two new compounds were established by 1D and 2D NMR and MS data....
Secondary metabolites from the fungus Cladosporium xylophilum [0.03%]
Cladosporium xylophilum菌的次生代谢产物研究
Lian Yang,Dong-Mei Lin,Xiu-Ming Cui et al.
Lian Yang et al.
A new cladosporol derivative xylophilum A (1), together with 10 known compounds (2-11), were isolated from the rice fermentation of the fungus Cladosporium xylophilum. Their structures were established by extensive spectroscopic methods and...
Bioactive prenylated c6-c3 derivatives from the roots of Illicium brevistylum [0.03%]
短梗拟豆蔻属植物根的生物活性香豆素类化合物
Jing-Yu Zhang,Hui-Lin Yang,Wen-Rui Li et al.
Jing-Yu Zhang et al.
Three new prenylated C6-C3 compounds (1-3), together with two known prenylated C6-C3 compounds (4-5) and one known C6-C3 derivative (6), were isolated from the roots of Illicium brevistylum A. C. Smith. The structures of 1-3 were elucidated...
Protective effects of bioactive components targeting β2-adrenergic receptors and muscarinic-3 acetylcholine receptor in Zhisou San on ovalbumin-induced allergic asthma [0.03%]
止嗽散中作用于β2肾上腺素受体和毒蕈碱型胆碱M3受体的活性成分对卵清蛋白致敏小鼠哮喘的保护效应研究
Feng-Wu Li,Na Zhou,Jing-Jing Li et al.
Feng-Wu Li et al.
One promising approach to overcome drug resistance in asthma treatments involves dual-target therapy, specifically targeting the β2 adrenergic receptor (β2-AR) and muscarinic-3 acetylcholine receptor (M3R). This study investigated the ant...
Screening of potential α-glucosidase inhibitors from astragalus membranaceus by affinity ultrafiltration screening coupled with UPLC-ESI-Orbitrap-MS method [0.03%]
基于亲和超滤筛选结合UPLC-ESI-Orbitrap-MS方法从膜荚黄芪中筛选潜在的α-葡萄糖苷酶抑制剂成分研究
Hong-Ping Wang,Zhao-Zhou Lin,Chen Zhao et al.
Hong-Ping Wang et al.
Astragalus membranaceus is a traditional Chinese medicine with multiple pharmacological activities. Modern pharmacological research has found that Astragalus membranaceus extract has an inhibitory effect on α-glucosidase, however, which co...