Preclinical determination of wound-healing activity of halibut oil cream in rat model of burn wound [0.03%]
牙鲆鱼油软膏烧伤伤口促愈合作用的临床前研究
S T Shukla,Anu Kaushik,Samiullah Allahbaksh Auti et al.
S T Shukla et al.
This study investigated the effects of halibut oil cream, containing omega-3 fatty acids, vitamins A and D, and hydroxyproline, on burn wound healing in rats. Acute dermal toxicity tests confirmed its nontoxicity. Wistar rats were divided i...
A new canthinone glycoside isolated from the root barks of Ailanthus altissima with NO inhibitory activity [0.03%]
一种产自毒参根皮中的具有抑制NO作用的新的咔啉类化合物
Jin-Feng Xue,Chen-Guang Zhao,Hao Pan et al.
Jin-Feng Xue et al.
One new canthinone glycoside (1), together with six known compounds (2-7) including three lignans (2-4), two coumarins (5-6) and one phenol (7) was isolated from the root barks of Ailanthus altissima. The structure of new compound 1 was est...
Characterization and identification of major flavonoids of bamboo leaf extract by HPLC/ESI-QTOF-MS/MS [0.03%]
高效液相色谱/电喷雾串联四极杆质谱联用技术分离鉴定竹叶黄酮类化合物
Si-Yue Shao,Jin Wang,Xi Yao et al.
Si-Yue Shao et al.
Bamboo leaf extract (BLE) is a pale brown powder extracted from bamboo leaves, and it is listed in the Chinese Standard GB-2760 as a legal and safe food additive. The present study aims to identify and characterize the major flavonoids in B...
Enhancement of aqueous solubility of hesperidin and naringenin utilizing hydrotropic solubilization technique: characterization and in vitro evaluation [0.03%]
应用水溶性增溶技术改善柚皮素和芸竹素的溶解度：表征与体外评价
Bhawna Arora,Viney Lather,Mallikarjuna Bandrehalli Pathalingappa et al.
Bhawna Arora et al.
The therapeutic potential of two important flavonoids, i.e. hesperidin and naringenin, remains unutilized due to pharmacokinetics issues, especially poor aqueous solubility. Hydrotropic solid dispersions with different agents like sodium sa...
A new cassane diterpenoid from the seed of Caesalpinia sappan [0.03%]
Caesalpinia sappan种子中新 cassane二聚茋茋茋三亚烷类化合物
Yue-Lin Zhao,Yue Jin,Zi-Ying Han et al.
Yue-Lin Zhao et al.
In this study, a previously undescribed cassane diterpenoid, named caesalpinin JF (1), along with two known cassane diterpenoids caesanine C (2) and tomocinol B (3), was isolated from 95% EtOH extract of the seeds of Caesalpinia sappan Linn...
Meng-Cheng Liu,Xiao-Jian Liao,Xi-Wen Xing et al.
Meng-Cheng Liu et al.
A new steroid, 2a-oxa-2-oxo-5β-hydroxy-3,4-dinor-24-methylcholesta-22E-ene (1), together with 10 known ones (2-11), was isolated from the marine sponge Cliona sp. The structures of these compounds were determined by the spectroscopic metho...
Synthesis of a collection of nootkatone analogues with diverse skeletons [0.03%]
具有多种骨架的香豆素类化合物的合成及生物活性研究
Yu-Ting Zhang,Jing Guo,Yu Zhao et al.
Yu-Ting Zhang et al.
A collection of ring distorted analogue of Nootkatone including 6 CTD (Complex to Diversity) compounds and 9 SAR (Structure Activity Relationship) compounds were synthesized utilizing the carbonyl group as a starting reaction point. ...
Design, synthesis and biological activity of oxyevodiamine-based histone deacetylase 6 inhibitors [0.03%]
基于氧代吴茱萸碱的组蛋白去乙酰化酶6抑制剂的设计、合成及活性研究
Si-Yuan Li,Jiang-Shan Guo,Ya-Jun Yang
Si-Yuan Li
Histone deacetylase 6 (HDAC6) was a potential target for Alzheimer's disease (AD). In this study, a series of novel oxyevodiamine-based HDAC6 inhibitors with a variety of linker moieties were designed, synthesized and evaluated. Compound 12...
Xia Zhang,Fang-Xin Wang,Zi-Wei Li et al.
Xia Zhang et al.
Four new alkaloids, arecatines A-D (1-4), were isolated from the peels of Areca catechu. Compound 1 is an unusual piperidine-pyridine hybrid alkaloid, whereas compounds 2-4 feature bis-piperidine alkaloids. Their structures were elucidated ...
Phosphatidylcholine and ceramide derivatives from white rot fungus Microporus xanthropus PP17-20 [0.03%]
Microporus xanthropus PP17-20菌株白色腐朽菌中磷脂酰胆碱和鞘氨醇类化合物的研究
Phongphan Jantaharn,Audomsak Churat,Sirirat Juanan et al.
Phongphan Jantaharn et al.
The undescribed phosphatidylcholine (1), along with twelve known compounds, was isolated from the cultures of white rot fungus Microporus xanthropus PP17-20. In this work the fungus was cultivated in Yeast-Malt extract medium to explore act...