Genome mining for ribosomally synthesized and post-translationally modified peptides (RiPPs) in Streptomyces bacteria [0.03%]
链霉菌基因组采矿寻找核糖体合成和翻译后修饰肽(RiPPs)
Abdullah Al Mamun,Khorshed Alam,Farjana Akter Koly et al.
Abdullah Al Mamun et al.
Ribosomally synthesized post-translationally modified peptides (RiPPs) are a novel category of bioactive natural products (NPs). Streptomyces bacteria are a potential source of many bioactive NPs. Limited opportunities are available to char...
Correction [0.03%]
改正
Published Erratum
Journal of Asian natural products research. 2024 Aug 14:1. DOI:10.1080/10286020.2024.2390261 2024
Integrated ceRNAs regulating relationship and bioinformatics analysis to study the molecular mechanisms of the inhibition of puerarin on bladder cancer cell [0.03%]
穿心莲内酯调节整合ceRNA网络及生物信息学分析以研究其抑制膀胱癌细胞的分子机制
Yu-Yang Ma,Wen Gao,Hao Wang et al.
Yu-Yang Ma et al.
Based on previous experiments, we demonstrated puerarin inhibited the proliferation of BC T24 cells. To further explore the molecular mechanisms, whole transcriptome sequencing combined with bioinformatics analysis was performed. The result...
Kaempferol inhibited invasion and metastasis of gastric cancer cells by targeting AKT/GSK3β pathway based on network pharmacology and molecular docking [0.03%]
基于网络药理学和分子对接研究槲皮素通过作用于AKT/GSK3β信号通路抑制胃癌细胞侵袭转移的作用机制探究
Xia-Qing Gao,Hai-Long Li,Meng Wang et al.
Xia-Qing Gao et al.
This study aims to explore the mechanisms of the inhibitory effect of kaempferol on the invasion and metastasis of gastric cancer (GC) cells through network pharmacology prediction and experimental verification. It identifies core targets v...
A review on phytochemicals as combating weapon for multidrug resistance in cancer [0.03%]
植物化学物质作为抗多重耐药癌症武器的综述
Sharwan Gupta,Anuradha Mehra,Rekha Sangwan
Sharwan Gupta
One can recognize multidrug resistance (MDR) and residue as a biggest difficulty in cancer specialist. Chemotherapy-resistant cancer may be successfully treated by combining MDR-reversing phytochemicals with anticancer drugs. Though, clinic...
Yu-Cheng Zheng,Wen-Jian Gu,Ren-Geng Shu et al.
Yu-Cheng Zheng et al.
Four new homoisoflavonoids, 7-hydroxy-3-[hydroxy(4'-methoxyphenyl)methyl]-benzopyran-4-one (1), (3R)-7, 8-dihydroxy-3-(4'-methoxybenzyl)-chroman-4-one (2), 7-hydroxy-3-(2'-hydroxy-4'-methoxybenzyl)-chroman-4-one (3), and 7-hydroxy-3-(2'-hyd...
A new isocoumarin derivative from endophytic fungus Pezicula neosporulosa VDB39 from Vaccinium dunalianum [0.03%]
一种寄生真菌Pezicula neosporulosa VDB39中新香豆素衍生物的分离与鉴定
Yuan-Cao Shu,Zhi-Yu Zhang,Xiao-Man Fu et al.
Yuan-Cao Shu et al.
Four isocoumarin derivatives (1-4) and five phenols (5-9) were obtained from the endophytic fungus Pezicula neosporulosa VDB39, which was isolated from the branches of Vaccinium dunalianum Wight (Ericaceae). Compound 1 is a new derivative o...
Four new lycoctonine-type C19-diterpenoid alkaloids from the whole plants of Delphinium kamaonense [0.03%]
来自毛脉翠雀花全草的新四环类原阿片烷型生物碱
Xing-Yao Li,Rui-Sheng Chen,Guo-Chang Li et al.
Xing-Yao Li et al.
Four new lycoctonine-type C19-diterpenoid alkaloids kamaonensines H-K (1-4) have been isolated from the whole plants of Delphinium kamaonense, together with 12 known compounds (5-16). Interestingly, kamaonensines 1-3 contained a rare nitron...
Bacterial metabolomics: current applications for human welfare and future aspects [0.03%]
细菌代谢组学:目前的人类福利应用和未来展望
Qazi Mohammad Sajid Jamal,Varish Ahmad
Qazi Mohammad Sajid Jamal
An imbalanced microbiome is linked to several diseases, such as cancer, inflammatory bowel disease, obesity, and even neurological disorders. Bacteria and their by-products are used for various industrial and clinical purposes. The metaboli...
Synthesis of scaberol C amino acid ester derivatives with anti-cancer activity [0.03%]
抗肿瘤活性瘢皮素C氨基酸酯衍生物的合成
Cheng-Long Li,Zheng Han,Dong-Ya Luo et al.
Cheng-Long Li et al.
A series of amino acid ester trifluoroacetate derivatives was synthesized from scaberol C. They were screened for their inhibitory activity against Non-Small Cell Lung Cancer (NSCLC) cells. Among them, compound 2 l showed significant cytoto...