Three new cyclopentanoid monoterpenes from the roots of Picrorhiza scrophulariiflora [0.03%]
喜马拉比苦根中环戊烷单萜的新成分研究
Xin-Yue Li,Jie Zhou,Guo-Ru Shi et al.
Xin-Yue Li et al.
Three new cyclopentanoid monoterpenes, neopiscrocins A-C (1-3), together with 14 known compounds (4-17), were isolated from the roots of Picrorhiza scrophulariiflora. The structres of these compounds were elucidated on the basis of their sp...
Synthesis, characterization and anticancer, antibacterial activities of pentacyclic triterpenoid glycoside derivatives [0.03%]
五环三萜苷衍生物的合成、表征及抗肿瘤和抗菌活性研究
Pan-Pan Wang,Yan-Dan Liu,Lan-Tian Cui et al.
Pan-Pan Wang et al.
As a kind of glycoside, pentacyclic triterpenoid saponins have good biological activities, such as anticancer, antibacterial, antiviral and hypoglycemic effects [1]. In this paper, twenty-four pentacyclic triterpenoid derivatives, including...
Rosmarinic acid suppresses the progression of COPD via Syk by modulating airway inflammation and epithelial apoptosis in vivo and in vitro [0.03%]
岩梗酸通过体内和体外调节气道炎症和上皮细胞凋亡抑制Syk介导的慢性阻塞性肺疾病的进展
Ji-Qiao Yuan,Xu-Yu Li,Yan-Nan Fan et al.
Ji-Qiao Yuan et al.
Rosmarinic acid (RosA), a hydrophilic phenolic compound found in various plants, has several biological effects such as anti-inflammatory and anti-apoptosis activities. However, its potential impact on chronic obstructive pulmonary disease ...
Study on the anti-HBV activity of matrine alkaloids from Oxytropis ochrocephala by MTT, 3d-QSAR, molecular docking and molecular dynamics simulation [0.03%]
基于MTT、三维定量构效关系、分子对接及分子动力学模拟研究麻黄碱类抗HBV活性研究
Ya-Kun Zhang,Jian-Bo Tong,Jing Tan et al.
Ya-Kun Zhang et al.
To elucidate the structure-activity relationship of 17 matrine alkaloids from Oxytropis ochrocephala Bunge, their effect on hepatitis B surface antigen (HBsAg) secretion was studied using the MTT assay. A 3D-QSAR analysis showed a strong co...
Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis [0.03%]
基于代谢组学分析的冬虫夏草治疗慢性阻塞性肺疾病大鼠氧化应激和炎症反应的潜在机制研究
Ying-Ying Liu,Gai-Jie Dou,Yuan-Can Xiao et al.
Ying-Ying Liu et al.
This study aimed to investigate the effects of wild Cordyceps sinensis on chronic obstructive pulmonary disease (COPD) rats through metabolomics approach, combined with biochemical parameters evaluations. Consequently, C. sinensis exhibited...
Proteomic analysis of two novel peptides from the Odontobuthus doriae scorpion venom [0.03%]
奥dontobuthus doriae蜈蚣毒液的蛋白质组分析及两种新肽的功能研究
Jamil Zargan,Ehsan Jahangirian,Haider A Khan et al.
Jamil Zargan et al.
The venom of the Odontobuthus doriae scorpion, prevalent in East Asia and Iran, has not been fully characterized. This study provides the first proteomic profile of O. doriae venom to explore its potential as a medical. 2D-PAGE analysis rev...
Chemical constituents from the endophytic fungus Aspergillus sp. S3 of Hibiscus tiliaceus [0.03%]
Hibiscus tiliaceus 内生真菌 Aspergillus sp. S3 的化学成分研究
Wen-Feng Chen,Meng-Meng Wang,Jing Tian et al.
Wen-Feng Chen et al.
A new sterol, aspersterol E (1), a newly discovered alkaloid, asperginine A (2), and five known compounds (3-7) were obtained from the endophytic fungus Aspergillus sp. S3 of Hibiscus tiliaceus Linn. The compounds were extracted from their ...
Therapeutic potential of xtr-miR-22-3p from Plastrum testudinis in acute promyelocytic leukemia [0.03%]
龟板xtr-miR-22-3p的急性早幼粒细胞白血病治疗潜力研究
Ming-Yang Chen,Meng Li,Qing-Yi Xu et al.
Ming-Yang Chen et al.
Acute promyelocytic leukemia (APL) is marked by a block at the promyelocyte stage. Treatments like ATRA and ATO face resistance and relapse issues. Plastrum testudinis, a traditional Chinese medicine, may offer therapeutic potential. This s...
Correlation analysis between potential hepatotoxicity and ingredient content of polygoni multiflori caulis [0.03%]
地菍茎抗肝毒性与成分含量的相关性分析
Ze-Ye Tan,Gui Zhou,Yi-Ming Feng et al.
Ze-Ye Tan et al.
Polygoni Multiflori Caulis (PMC) is commonly used in clinical practice. While the adverse reactions of Polygoni Multiflori Radix (RPM) are well-known, the potential adverse reactions of PMC are often neglected. This article aims to clarify ...
Quantitative predictive model for screening optimal processing methods of Polygonati rhizoma [0.03%]
黄精炮制工艺优选的量化预测模型筛查研究
Shi-Jie Bi,An-Lei Yuan,Zi-Jun Chen et al.
Shi-Jie Bi et al.
Polygonati rhizoma (Huangjing in Chinese) is a common clinical tonic with the traditional effects of tonifying Qi, nourishing Yin. However, the lack of precise control of processing parameters has led to the uneven quality of processed Huan...