Yu-Shuang Wen,Li Jiang,Yang Wang et al.
Yu-Shuang Wen et al.
Three new compounds, including two glycosides, named gerbelavinsides E/G (1/2), and a flavone, named gerbelavin G (3), were isolated from 50% ethanol extract of Gerbera delavayi. Their structures were elucidated based on HR-ESI-MS, IR, UV a...
A rare prenylated isoflavone-quinone from the roots of Flemingia philippinensis [0.03%]
菲律宾岩黄耆根中的一种罕见香豆素茋醌类化合物
Sheng-Li Niu,Xiao-Zhuo Han,Yan-Ping Wang et al.
Sheng-Li Niu et al.
In order to make more rational use of Flemingia Philippinensis, a systematic separation from the roots of F. philippinensis was performed in the current study. The investigation of chemical constituents resulted in the isolation of a rare p...
Taxifolin ameliorates the D-galactose-induced aging of mouse hippocampal neurons HT-22 cells through modulating SIRT1/p53 and PI3K/AKT signaling pathways [0.03%]
taxifolin通过调节SIRT1/p53和PI3K/AKT信号通路改善D-半乳糖致小鼠海马神经元HT-22细胞衰老
Xing-Long Liu,Shuang Zu,Hao Yue et al.
Xing-Long Liu et al.
By establishing an in vitro model of D-Gal-induced brain neuronal cell (HT-22) senescence, it was found that TAX treatment significantly increased the activities of SOD and GSH, while decreasing MDA levels in aging HT-22 cells, indicating t...
Yan-Fei Liu,Shi-Shan Yu
Yan-Fei Liu
The new natural products reported in 2023 in peer-reviewed articles in journals with good reputations were reviewed and analyzed. The advances made by Asian research groups in the field of natural products chemistry in 2023 were summarized....
Recent advances in natural products and derivatives with antiviral activity against respiratory syncytial virus (RSV) [0.03%]
近年来抗呼吸道合胞病毒(RSV)活性的天然产物及衍生物的研究进展
Ameena Tur Rasool,Erguang Li,Ahsan Nazir
Ameena Tur Rasool
Respiratory syncytial virus (RSV) is a widespread viral infection that causes millions of high-risk illnesses annually. Medicinal herbs such as ginseng root, echinacea purpurea, and radix astragali have a positive effect on antiviral activi...
Monoterpene indole glycoalkaloids from the hook-bearing branches of Uncaria rhynchophylla [0.03%]
Uncaria rhynchophylla钩枝中的单萜吲哚苷类生物碱成分研究
Lu Rao,Fei Chen,Ming-Hui Gao et al.
Lu Rao et al.
Twelve monoterpene indole glycoalkaloids, comprising of three new ones, 19-epi-rhynchophylloside A (1), 7-epi-rhynchophylloside A (2), and 7-epi-anthocephalusine A (3), were isolated from the hook-bearing branches of Uncaria rhynchophylla. ...
Caenorhabditis elegans as in vivo model for the screening of natural plants-derived novel anti-aging compounds: a short introduction [0.03%]
模式生物线虫作为中药抗衰老活性成分筛选模型系统的技术简介
Samah H O Zarroug
Samah H O Zarroug
The global aging population highlights the need for effective anti-aging treatments. Natural products show promise, but thorough evaluation requires in vivo models due to the complexity of aging. Ethical concerns are driving a shift from tr...
A regio-specific 4 '- O-methyltransferase from Epimedium pseudowushanense regiospecifically catalyzing 8-prenylkeampferol to icaritin [0.03%]
一种Epimedium pseudowushanense植物中特定位点的4'-O-甲基转移酶催化8-异丁烯基高良姜素生成斑灵素的研究
Ke-Ping Feng,Ji-Mei Liu,Ri-Dao Chen et al.
Ke-Ping Feng et al.
Epimedium is widely used in traditional Chinese medicine and contains rich bioactive compounds. These compounds often have a methyl group at their 4'-OH position catalyzed by methyltransferases. Therefore, studying methyltransferases in Epi...
Three new coumarins from Notopterygium incisum with potential anti-inflammatory activity [0.03%]
三种防风草中的新型香豆素及其潜在的抗炎活性
Xue-Yan Huo,Meng-Dan Liu,Yu-Hui Chen et al.
Xue-Yan Huo et al.
Three previously undescribed coumarins (1-3) were obtained from the roots of Notopterygium incisum. Their chemical structures were elucidated using a variety of spectroscopic techniques and chemical calculations. The inhibitory effects of t...
Potential benefits of marine-derived compounds for slowing the advancement of Alzheimer's disease [0.03%]
海洋衍生化合物延缓阿尔茨海默病进展的潜在益处
Aditya Malan,Manjusha Choudhary,Prabhjeet Kaur Bamrah et al.
Aditya Malan et al.
The incidence of Alzheimer's is increasing and poses a significant social and economic burden. The pathogenesis involved in the expansion of AD includes neuronal oxidative damage, tau phosphorylation, amyloid beta aggregation, neuroinflamma...