Human poisoning with glyphosate-surfactant herbicides: Retrospective analysis of mortality outcomes of patients treated in a poison center [0.03%]
草甘膦表面活性剂类除草剂中毒的住院病例回顾性分析及死亡率研究
Kuan-Hung Liu,Shu-Sen Chang,Chao-Ying Tu et al.
Kuan-Hung Liu et al.
Introduction: The toxicity and carcinogenicity of glyphosate have long been debated. Nevertheless, the mortality rate in patients with acute glyphosate-surfactant poisoning varies across different groups. ...
LncRNA-NEAT1 facilitates autophagy to boost pemetrexed resistance in lung adenocarcinoma via the mir-379-3p/HIF1A pathway [0.03%]
长链非编码RNA-NEAT1通过mir-379-3p/HIF1A途径促进自噬以增强肺腺癌中培美曲塞耐药性
Wei Hu,Wenjun Cao,Jiheng Liu
Wei Hu
Background: As a primary chemotherapeutic agent for lung adenocarcinoma (LUAD), pemetrexed (PEM) faces the challenge of resistance development in cancer cells due to its chronic use, which compromises its therapeutic bene...
In silico evaluations of phytochemicals from Withania somnifera exhibiting anticancer activity against NAD[P]H-quinone oxidoreductase [0.03%]
一种展示抗癌症活性的Withania somnifera植物化学成分的计算机评估研究:NAD[P]H-喹啉氧化还原酶
Sushma Jahagirdar,Harshini Praveen Kumar,Smitha S Bhat et al.
Sushma Jahagirdar et al.
Background: Cancer is a leading cause of death globally and in the US, prompting research into medicinal plants with anticancer properties. Withania somnifera, or Ashwagandha, is one such plants, known for its diverse pha...
Discovering the most impactful treatments for aluminum phosphide cardiotoxicity gleaned from systematic review of animal studies [0.03%]
系统综述发现的动物实验中最有效的铝磷心脏毒性的治疗方法
Saeed Aghebat-Bekheir,Mohammad Abdollahi
Saeed Aghebat-Bekheir
Introduction: Aluminum phosphide (AlP) is a chemical compound that can cause death in some countries. AlP inhibits the functioning of cytochrome C oxidase in the mitochondria of cardiomyocytes, leading to toxicity. Oxidat...
Aluru Parithathvi,Neha Choudhari,Herman S Dsouza
Aluru Parithathvi
Lead (Pb) has become a major environmental contaminant. There are several ways in which lead can enter the human body and cause toxic effects on human health. This review focuses on the impact of lead toxicity at prenatal and early life sta...
Subchronic oral toxicity assessment of Bacillus velezensis strain BV379 in sprague-dawley rats [0.03%]
枯草芽孢杆菌BV379菌株在Sprague-Dawley大鼠中的亚慢性经口毒性评估研究
Mark R Bauter,Laura M Brutscher,Laurie C Dolan et al.
Mark R Bauter et al.
Introduction: The spore-forming bacterial species Bacillus velezensis is commonly utilized in feed for livestock and aquaculture. In recent years, there has been increased interest in introducing B. velezensis into human ...
Protective effects of atractylenolide III on oxygen-glucose-deprivation/reperfusion-induced injury in HT22 cells [0.03%]
苍术素III通过调节自噬对HT22细胞OGD/R损伤的保护作用研究
Roujia Guo,Siqi Quan,Yuan Liu et al.
Roujia Guo et al.
Background: Atractylenolide III (ATL III) is a natural bioactive compound, that possesses anti-inflammatory, antioxidant, and neuroprotective properties. However, whether ATL III can protect against neuronal injury induce...
CircRNA_001373 promotes liver fibrosis by regulating autophagy activation in hepatic stellate cells via the miR-142a-5p/Becn1 axis [0.03%]
Circular RNA_001373通过miR-142a-5p/Becn1轴调节肝星状细胞自噬激活促进肝纤维化
Ying Cao,Huan Yang,Bingying Wang
Ying Cao
The purpose of this study was to investigate the regulatory role and underlying mechanisms of circRNA_001373 in the hepatic stellate cell (HSC) activation. Quantitative real-time polymerase chain reaction was used to detect the expression o...
Sulforaphane triggers Sirtuin 3-mediated ferroptosis in colorectal cancer cells via activating the adenosine 5'-monophosphate (AMP)-activated protein kinase/ mechanistic target of rapamycin signaling pathway [0.03%]
萝卜硫素通过激活腺苷酸活化蛋白激酶/哺乳动物雷帕霉素靶蛋白信号通路触发Sirtuin 3介导的结直肠癌细胞铁死亡
Bo Hu,Ping Cao,Jing-Hui Wang et al.
Bo Hu et al.
Objective: This study aimed to explore the expression and biological functions of SIRT3 in colorectal cancer cells (HCT-116), the impacts of sulforaphane on the ferroptosis of HCT-116 cells and the involvement of the SIRT...
Nomogram for predicting mechanical ventilation need among acutely intoxicated patients with impaired consciousness: Correspondence [0.03%]
预测急性中毒伴意识障碍患者机械通气需求的计算图表：信函回复
Hineptch Daungsupawong,Viroj Wiwanitkit
Hineptch Daungsupawong