Establishment of a rat model of bronchopulmonary dysplasia complicated with pulmonary hypertension and its potential applications [0.03%]
支气管肺发育不良合并肺高压大鼠模型的建立及其潜在应用价值研究
Suixin Liang,Xin Wang,Yemei Wu
Suixin Liang
ObjectiveBronchopulmonary dysplasia (BPD), a common chronic lung disease in premature infants, is frequently complicated by pulmonary hypertension (PH), a dangerous condition characterized by elevated pulmonary vascular pressure. At present...
Pulmonary iron oxide (Fe3O4) nanoparticle-biomolecule interactions modified during aging and metabolic syndrome disease progression [0.03%]
老化和代谢综合征疾病进展过程中肺铁氧化物(NP-Fe3O4)纳米粒子-生物分子相互作用的改变
Akshada Shinde,Li Xia,Venkatesh P Thirumalaikumar et al.
Akshada Shinde et al.
IntroductionAging and metabolic disease enhance inhaled particulate toxicity. Nanoparticles (NPs) are rapidly coated with biomolecules forming a biocorona (BC), upon entering the body and may contribute to the susceptibility. Aging and meta...
Inhibition of store-operated calcium entry mitigates lipopolysaccharide-induced hepatotoxicity via modulating inflammatory and oxidative stress responses [0.03%]
储运营钙进入的抑制通过调节炎症和氧化应激反应缓解脂多糖诱导的肝毒性
Mohammed Alqinyah,Abdullah S Alhamed,Yasseen A Alassmrry et al.
Mohammed Alqinyah et al.
IntroductionHepatotoxicity can arise secondary to several medical conditions, including inflammation, sepsis, and therapy. Lipopolysaccharide (LPS) can activate diverse inflammatory pathways and has been implicated in hepatotoxicity. The st...
Stevioside inhibits colorectal cancer progression by regulating macrophage polarization [0.03%]
Stevioside通过调节巨噬细胞极化抑制结直肠癌进展
Yang Bai,Yuefei Wang,Fang Zhang et al.
Yang Bai et al.
ObjectiveThe study aimed to explore the inhibitory effect of stevioside on colorectal cancer and its molecular mechanism.MethodsColorectal cancer cells were selected for functional testing, including the following groups: 0 μM stevioside, ...
Predictive factors of severe outcome in glufosinate ammonium poisoning: A retrospective study in Vietnam [0.03%]
草甘膦铵中毒严重结局的预测因素：越南的回顾性研究
Dang Duc Nguyen,Nguyen Hong Anh Lam,Dang Bach Nguyen
Dang Duc Nguyen
BackgroundGlufosinate ammonium (GLA) is a widely used herbicide in rural Vietnam, often associated with severe toxicity. Given the limited diagnostic resources at primary care levels, identifying simple and effective predictors of severity ...
Usnic Acid induces dual-pathway apoptosis in SKOV-3 ovarian cancer cells via PARP1 inhibition and MAPK pathway activation [0.03%]
H曲松通过PARP1抑制和MAPK途径活化诱导SKOV-3卵巢癌细胞双重途径凋亡
Mehmet Kürşat Derici,Mine Ensoy,Pelin Mutlu et al.
Mehmet Kürşat Derici et al.
IntroductionDue to its silent clinical progression and diagnosis often occurring at advanced stages, ovarian cancer continues to be a major contributor to gynecological cancer-related mortality worldwide. Recent evidence underscores the cri...
Nickel; a metal with threats to human health, focusing on its intoxication mechanisms [0.03%]
镍对人体健康的威胁及中毒机制研究
Mehrdad Rafati Rahimzadeh,Mehravar Rafati Rahimzadeh,Sohrab Kazemi et al.
Mehrdad Rafati Rahimzadeh et al.
Background and ObjectiveNi is an important metal found in the human environment, including air, water, soil, food, kitchenware, and jewelry. It is widely used in electrical engineering, medicine, and industry. Ni compounds, whether insolubl...