Decoding ortho regiospecificity and high endo stereoselectivity in pyrazole synthesis via the activation/strain model [0.03%]
利用活化/环张力模型解析吡唑合成中的ortho区域选择性和高endo立体选择性
Saeedreza Emamian,Ali Mohammad Shariati,Majid Salami et al.
Saeedreza Emamian et al.
A comprehensive density functional theory investigation was conducted to elucidate the regio- and stereoselectivity of the 1,3-dipolar cycloaddition reaction (13-DCR) between a diazo compound (1,3-dipole D-1) and an electron-deficient nitro...
Photo-induced radical trifluoromethylation/dearomatization of 3-substituted indoles [0.03%]
光诱导的3-取代吲哚的自由基三氟甲基化/脱芳香化反应
Yuyu Lv,Zhoubin Deng,Zhijun Zhu et al.
Yuyu Lv et al.
A visible-light-induced cascade radical trifluoromethylation/cyclization/dearomatization reaction between 3-substituted indoles and CF3Br in the presence of 4CzIPN and K2CO3 has been developed. This protocol provided a facile, efficient and...
Design, synthesis and characterization of a carbonyl-containing high-density pyrazolotriazine-based energetic compound [0.03%]
一种含羰基高密度杂环硝结构炸药候选材料的设计、合成与表征研究
Huanyu Sun,Zhiwei Zeng,Chunhui Chen et al.
Huanyu Sun et al.
Constructing novel high-energy frameworks to achieve an ideal balance between high energy density and good stability is a common goal in the field of energetic materials. In this study, a novel high-energy density compound was designed and ...
Recent advances in photo-induced synthesis of polycyclic quinazolinones from unactivated alkene-tethered quinazolinones [0.03%]
光诱导合成茋类茋骨架茋化合物的研究进展
Yu-Xin Luo,Fan-Lin Zeng,Teck-Peng Loh et al.
Yu-Xin Luo et al.
In recent years, polycyclic quinazolinone derivatives have attracted considerable attention from the synthetic organic chemistry community owing to their diverse pharmacological and biological properties. This review comprehensively summari...
One-pot three-component synthesis of benzo[ h]isoquinolin-3-ones via rhodium(III)-catalyzed C-H activation [0.03%]
通过Rh(III)催化C-H活化一锅法合成三组分苯并[h]异喹啉-3-酮类化合物
Weihong Song,Xiaomei Jiang,Weiguo Yu et al.
Weihong Song et al.
A Rh(III)-catalyzed one-pot synthesis of benzo[h]isoquinolin-3-ones from 1-naphthaldehyde, aniline and diazo compounds has been realized, with an imine serving as the directing group which was generated through aldimine condensation in situ...
Recent advances in electrochemical C-H chalcogenation (O/S/Se) of heteroaromatics [0.03%]
异芳烃电化学C-H硫属元素化(O/S/Se)研究进展
Xianhui You,Xiaotong Gao,Yuechuan Wang et al.
Xianhui You et al.
Chalcogenated heteroaromatics containing C-O/S/Se bonds are widely prevalent in natural products, medicines, and bioactive structures, and numerous elegant methodologies for the direct synthesis of these compounds have been developed in an ...
Shaotong Qiu,Yangxin Mao,Zhicheng Yang et al.
Shaotong Qiu et al.
An unprecedented Cu-catalyzed oxygen-transferring hydrazonation reaction of enynones with arylsulfonylhydrazines has been developed. Featuring high efficiency, broad substrate scope and mild reaction conditions, this protocol provides a pra...
Substituted pyridil-imidazole derivatives as red-green-blue (RGB) as well as white-light emitters [0.03%]
含取代吡啶-咪唑衍生物的红绿蓝（RGB）及白光发射体
Raju Biswas,Tuhin Abedin,Srikanta Karmakar et al.
Raju Biswas et al.
A series of 2-(2-pyridyl)imidazole-based compounds were synthesized via condensation of 2,2'-pyridil with p-substituted benzaldehydes and thoroughly characterized by standard analytical tools and spectroscopic techniques, including the sing...
Phylogeny-directed discovery and mutagenesis of a tricyclic gersemiane synthase [0.03%]
定向进化发现和诱变三环gersemiane合酶
Xiaochen Chen,Bao Chen,Baofu Xu
Xiaochen Chen
Eunicellane diterpenoids, characterized by a 6,10-bicyclic core, are prone to undergo further cyclization into gersemiane diterpenoids via acid- or epoxidation-mediated protonation. However, it remains unclear whether classical type I terpe...
Six-membered cyclic sulfamidate imines: functionalization and cyclization reactions [0.03%]
六元环亚磺酰亚胺：功能化和cyclization反应
Fatemeh Doraghi,Mohammad Hadi Edareh,Bagher Larijani et al.
Fatemeh Doraghi et al.
Six-membered cyclic sulfamidate imines are a class of readily accessible and stable imines that have proven to be important building blocks in constructing functionalized cyclic N-sulfamidates and sulfamidate-fused heterocycles. They can un...