Impact of pesticides lambda-cyhalothrin, emamectin benzoate, and thiophanate-methyl used alone and in mixtures on reproduction and oxidative stress markers in male Wistar rats [0.03%]
单一使用和混合使用杀虫剂lambda-氰戊菊酯、emamectin苯甲酸盐和噻菌酰对雄性Wistar大鼠生殖及氧化应激标志物的影响
Narimene Chelbi,Leila Mallem,Hanene Chaabane et al.
Narimene Chelbi et al.
Pesticide exposure is a growing public health concern, particularly in agricultural regions where workers and communities encounter multiple chemical compounds simultaneously. Although previous studies have investigated the reproductive tox...
Hematological changes in formaldehyde-exposed workers: A critical review and meta-analysis [0.03%]
甲醛暴露工人血液系统变化的荟萃分析及机制探讨
Reza Pourbabaki,Fatemeh Rahimian,Mohammad Ebrahim Ghaffari et al.
Reza Pourbabaki et al.
Formaldehyde (FA) is a widely used chemical with known carcinogenic properties, particularly for the upper respiratory tract. Concerns about probable FA-induced hematotoxicity and leukemia have sparked investigations into its health risks. ...
Effects of sub-acute aluminium phosphide exposure on hepatorenal biomarkers and antioxidant defense in rats [0.03%]
亚急性磷化铝暴露对大鼠肝肾生物标志物和抗氧化防御的影响
Ibtissem Anguel,Leila Kirane-Amrani,Tahar Tata et al.
Ibtissem Anguel et al.
Aluminium phosphide (AlP) is a well-known toxic pesticide, but its dose-dependent toxicity and the distinction between safe and harmful exposure levels remain poorly established. Thus, the present study aimed to investigate the dose-depende...
Toxicological implications and human health risk assessment of heavy metal contaminated green leafy vegetables and their cultivated soil [0.03%]
重金属污染的绿叶蔬菜及其栽培土壤的毒理学意义和人体健康风险评估
Varun Shankarappa,Prabhurajeshwar Chidre,Ajay Kumar Oli et al.
Varun Shankarappa et al.
In the present study, fourteen green leafy vegetables, including spinach, coriander, spring onion, curry, dill, fenugreek, green amaranth, and red amaranth, along with their rhizospheric soils from Chitradurga, Davangere, Tumkur, and Haveri...
Molecular mechanisms of heavy metal-induced cancer: Insights from animal models and human implications [0.03%]
重金属致癌症的分子机制：动物模型及对人体致癌的启示
Sneha Dhanasekaran,Kottila Veettil Dhaneesh
Sneha Dhanasekaran
Heavy metals and metalloids, including arsenic (As), cadmium (Cd), chromium (Cr), nickel (Ni), lead (Pb), and mercury (Hg), are well-recognised human carcinogens, and the molecular mechanisms underlying their carcinogenicity are incompletel...
The effects of flurochloridone exposure during pregnancy on maternal and fetal development [0.03%]
孕期接触氟氯酮对母体和胎儿发育的影响
Rui Li,Su Zhou,Hongyan Zhu et al.
Rui Li et al.
Flurochloridone (FLC) was classified as "May cause harm to the unborn child" by the European Food Safety Authority (EFSA). Because of the potential for occupational exposure to FLC, and the lack of reported maternal and fetal data, we inves...
The history of the Toxicology Roundtable-75 years of scientific discussion [0.03%]
毒理学圆桌会议的历史——75年的科学讨论
David G Serota,Christopher N Papagiannis
David G Serota
Perfluorooctane sulfonate (PFOS) increases metastatic potential of thyroid cancer cells in correlation with activation of multiple invasion-related signaling proteins [0.03%]
全氟辛烷磺酸(PFOS)通过激活多个侵袭相关信号蛋白增加甲状腺癌细胞的转移潜能
Phichamon Phetchahwang,N Monique Paricharttanakul,Kriengsak Lirdprapamongkol et al.
Phichamon Phetchahwang et al.
Perfluorooctane sulfonate (PFOS) is a man-made chemical widely used in many products and acts as an endocrine-disrupting chemical (EDC). PFOS has spread to the environment through industrial manufacturing processes and disposal of PFOS-cont...
Biological and computational evidence of dinotefuran-DNA interactions: A combined in vitro and in silico study [0.03%]
丁硫克百威与DNA相互作用的生物和计算证据：体外和分子对接研究
Mazlume Piril Coskun,Ayla Celik,Hakan Arslan
Mazlume Piril Coskun
The potential of the neonicotinoid insecticide dinotefuran to induce oxidative DNA damage was evaluated in human peripheral blood lymphocyte cultures at three concentrations (0.05, 0.15, and 0.30 µg/mL) using the single-cell gel electropho...
Dibromoacetonitrile mediated depression-like behavior in mice and induced HT22 cytotoxicity through the MKP-1/P38 MAPK signaling pathway and the antagonistic effect of N-acetylcysteine [0.03%]
N-乙酰半胱氨酸介导的双溴乙腈小鼠抑郁样行为和诱导HT22细胞毒性通过MKP-1 / P38 MAPK信号通路及拮抗作用
Cong Qi,Xinwei Xu,Lan Zhang et al.
Cong Qi et al.
Environmental pollutants are an important cause of depression. Dibromoacetonitrile (DBAN) is a disinfection by-product, which is neurotoxic and induces oxidative stress. This study aimed to elucidate whether and how DBAN provoked depression...