Qian Wang,Zhicai Yu,Zhixin Song et al.
Qian Wang et al.
Background: Sepsis is a severe condition causing organ failure due to an abnormal immune reaction to infection, characterized by ongoing excessive inflammation and immune system issues. Osteopontin (OPN) is secreted by va...
TRPV4 modulates inflammatory responses and apoptosis in enteric glial cells triggered by Clostridioides difficile toxins A and B [0.03%]
TRPV4调节难辨梭菌A和B毒素触发的肠胶质细胞炎症反应和凋亡
Dvison de Melo Pacífico,Deiziane Viana da Silva Costa,Maria Lucianny Lima Barbosa et al.
Dvison de Melo Pacífico et al.
Clostridioides difficile, a spore-forming anaerobic bacterium, is the primary cause of hospital antibiotic-associated diarrhea. Key virulence factors, toxins A (TcdA) and B (TcdB), significantly contribute to C. difficile infection (CDI). Y...
Correction: Progress of CCL20-CCR6 in the airways: a promising new therapeutic target [0.03%]
纠正：CCL20-CCR6在气道中的进展：一个有前景的新治疗靶点
Ya -Jing Li,Wan-Li Geng,Chen-Chen Li et al.
Ya -Jing Li et al.
Correction: Downregulation of miR-223 promotes HMGB2 expression and induces oxidative stress to activate JNK and promote autophagy in an in vitro model of acute lung injury [0.03%]
纠正：miR-223下调通过诱导氧化应激激活JNK促进HMGB2表达从而在急性肺损伤的体外模型中诱导自噬
Hao-Yu Tan,Bei Qing,Xian-Mei Luo et al.
Hao-Yu Tan et al.
Progress of CCL20-CCR6 in the airways: a promising new therapeutic target [0.03%]
气道中CCL20-CCR6的发展：一个有前景的新治疗靶点
Ya -Jing Li,Wan-Li Geng,Chen-Chen Li et al.
Ya -Jing Li et al.
The chemokine CCL20, a small cytokine that belongs to the C-C chemokine family, interacts with its homologous receptor CCR6, which is expressed on wide range of cell types. According to current research, the CCL20-CCR6 has been established ...
Basement membranes' role in immune cell recruitment to the central nervous system [0.03%]
基底膜在免疫细胞招募至中枢神经系统中的作用
Shaun A Wright,Rachel Lennon,Andrew D Greenhalgh
Shaun A Wright
Basement membranes form part of the extracellular matrix (ECM), which is the structural basis for all tissue. Basement membranes are cell-adherent sheets found between cells and vascular endothelia, including those of the central nervous sy...
Effect of statins on arterial wall inflammation as assessed by 18F-FDG PET CT: an updated systematic review and meta-analysis [0.03%]
他汀类药物对动脉壁炎症影响的系统性回顾和meta分析的更新研究：基于18F-FDG PET/CT评估结果
Tannaz Jamialahmadi,Željko Reiner,Luis E Simental-Mendia et al.
Tannaz Jamialahmadi et al.
Background: Pathogenesis of atherosclerosis is largely mediated by inflammatory process. Statins are lipid-lowering drugs which also have anti-inflammatory effects. 18 fluorine radiolabeled fluorodeoxyglucose (18 F-FDG) p...
Regulatory effects of statins on CCL2/CCR2 axis in cardiovascular diseases: new insight into pleiotropic effects of statins [0.03%]
他汀类药物对心血管疾病中CCL2/CCR2轴的调节作用：他汀类药物多效性的新见解
Hanieh Gholamalizadeh,Behzad Ensan,Sercan Karav et al.
Hanieh Gholamalizadeh et al.
Background: HMG-CoA reductase inhibitors are well-known medications in the treatment of cardiovascular disorders due to their pleiotropic and lipid-lowering properties. Herein, we reviewed the effects of statins on the CC...
Resolution of acute inflammation induced by monosodium urate crystals (MSU) through neutrophil extracellular trap-MSU aggregate-mediated negative signaling [0.03%]
单钠尿酸盐晶体诱导的急性炎症通过中性粒细胞胞外诱捕网-单钠尿酸盐晶体凝集物介导的负向信号而缓解
Cheng-Hsun Lu,Chieh-Yu Shen,Ko-Jen Li et al.
Cheng-Hsun Lu et al.
Background: Polymorphonuclear neutrophils (PMN) activation by monosodium urate crystals (MSU) is crucial to acute gouty arthritis and subsequent spontaneous remission within 7-10 days. Activated PMNs release neutrophil ex...
Macrophage involvement in idiopathic inflammatory myopathy: pathogenic mechanisms and therapeutic prospects [0.03%]
原发性炎症性肌病中的巨噬细胞作用机制及治疗前景
Ziqi Li,Huan Liu,Qibing Xie et al.
Ziqi Li et al.
Idiopathic inflammatory myopathies are a group of systemic autoimmune diseases characterized by chronic muscle inflammation and diverse clinical manifestations. Macrophages, pivotal components of innate immunity, are implicated in immune re...