Myeloperoxidase regulates hypoxia-induced inflammation and oxidative stress in liver-spleen axis [0.03%]
Yonggui Li,Xiaoli Liu,Lingming Zhang et al.
Yonggui Li et al.
Background: High-altitude hypobaric hypoxia induces inflammation and oxidative stress, yet the role of myeloperoxidase (MPO) in this pathology remains incompletely understood. This study aimed to investigate whether MPO m...
Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast [0.03%]
_RESOLUTION_D1通过非TGF-β依赖途径抑制衰老相关分泌表型独立于心脏成纤维细胞分化为肌成纤维细胞
Mauricio Román,José Miguel Osorio,Claudio Espinoza-Pérez et al.
Mauricio Román et al.
Dihydromyricetin exerts neuroprotective effects in acute spinal cord injury by inhibiting NLRP3/Caspase-1 inflammasome through gut microbiome modeling [0.03%]
二氢杨梅素通过重塑肠道菌群抑制NLRP3/Caspase-1炎症小体在急性脊髓损伤中发挥神经保护作用
Yi Yang,Chao Kang,Rizhao Pang et al.
Yi Yang et al.
WWC1 deficiency exacerbates sepsis-induced lung injury by promoting NETosis, M1 and M2b macrophage recruitment, and pyroptosis via YAP1 and STING pathways [0.03%]
WWC1通过YAP1和STING通路促进NETosis、M1和M2b型巨噬细胞募集及pyroptosis从而加剧脓毒症诱导的肺损伤
Yifeng Chen,Han Xu,Chengyang He et al.
Yifeng Chen et al.
Hypoxia synergizes cGAS-STING activation and AKT1 phosphorylation to drive pulmonary inflammation in one-lung ventilation: therapeutic attenuation by RU.521 and MK2206 [0.03%]
缺氧通过cGAS-STING活化和AKT1磷酸化驱动单肺通气的肺部炎症：RU.521和MK2206的治疗作用
Jiangsheng Zhang,Yuntao Zou,Dongni Chen et al.
Jiangsheng Zhang et al.
Background: To explore the mechanisms involved in hypoxia-induced acute lung injury (ALI) and oxidative stress during one-lung ventilation (OLV) in order to find pharmacological interventions that can attenuate OLV injury...
Organ-specific inflammatory profiles during sepsis: divergent macrophage polarization and oxidative stress response in lung and liver in mouse model of caecal ligation and puncture [0.03%]
腹腔镜下结肠穿孔模型脓毒症时机体器官特异性炎症反应：肺脏及肝脏巨噬细胞极化和氧化应激反应的差异性研究
Aude Bodin,Abdessalem Hammed,Mathieu Magnin et al.
Aude Bodin et al.
Electroacupuncture activates the TET1/PPARα pathway to protect mitochondrial function in MASLD [0.03%]
电针通过激活TET1/PPARα通路保护肝脏线粒体功能防治非酒精性脂肪肝病
Shurui Yang,Yiwen Li,Bowen Lu et al.
Shurui Yang et al.
Ubiquitination-mediated PRDX2 alleviates intervertebral disc degeneration via restraining TBHP-induced nucleus pulposus cell apoptosis, ferroptosis and ECM degradation [0.03%]
泛素化介导的PRDX2通过限制TBHP诱导的髓核细胞凋亡、铁死亡和ECM降解来缓解椎间盘退变
Fanguo Kong,Jiyao Luan,Qipeng Pan et al.
Fanguo Kong et al.
Oral sodium butyrate supplementation acts on intestinal dysbiosis and resolves spinal cord neuroinflammation and nociceptive neuron sensitization [0.03%]
口服丁酸钠补充剂作用于肠道菌群失调，缓解脊髓神经炎症和伤害性感觉神经元敏化
Antimo Fusco,Federica Ricciardi,Michela Perrone et al.
Antimo Fusco et al.
CRSwNP-derived cells retain native disease-relevant characteristics in vitro [0.03%]
CRSwNP来源的细胞在体外保留了其固有的疾病相关特性
Philipp Kühnel,Luisa Vossler,Melanie Siemen et al.
Philipp Kühnel et al.