Differences in systemic inflammation and prethrombotic biomarkers between AECOPD patients with and without pulmonary hypertension [0.03%]
急性加重期慢性阻塞性肺疾病合并与不合并肺动脉高压患者的全身炎症及促凝状态差异研究
Xiao Bo Wang,Zhu Qi Gao,Ying Yu et al.
Xiao Bo Wang et al.
Objective: The relationship between inflammatory cytokines and prothrombotic markers with PH during the acute phase of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) remains unclear. This study aims ...
Administration of human macrophage colony-stimulating factor-mFc fusion protein increases macrophage phagocytic capacity and stimulates liver regeneration in mice [0.03%]
人源巨噬细胞集落刺激因子-mFc融合蛋白的给药可增加巨噬细胞吞噬能力并促进小鼠肝再生
Philip J Starkey Lewis,Jennifer A Cartwright,Lara Campana et al.
Philip J Starkey Lewis et al.
Background: Acute and chronic liver diseases are rising contributors of the worldwide healthcare burden. Inflammation plays a key role in progression of both acute and chronic disease, and effective treatments are limited...
Editorial Expression of Concern: The occurrence and development of radiation-induced lung injury after interstitial brachytherapy and stereotactic radiotherapy in SD rats [0.03%]
撤稿声明：后装放疗与立体定向放射治疗SD大鼠放射性肺损伤的发生及发展
Zhuo Chen,Bin Wang,Zhouxue Wu et al.
Zhuo Chen et al.
FOXD2-AS1/miR-185-5p/CDC42 axis in chronic obstructive pulmonary disease: clinical significance and mechanistic insights [0.03%]
慢性阻塞性肺疾病中FOXD2-AS1/miR-185-5p/CDC42轴的意义及机制研究
Jin Xu,Xiaojuan Hu,Zaiyuan Wang et al.
Jin Xu et al.
Background: Long non-coding RNA (lncRNA), a key molecule within gene expression regulatory network, is important in various respiratory diseases. This study assessed the expression changes and regulatory mechanism of lncR...
A spotlight on the inflammatory role of uremic toxins in the dysbiosis-CKD axis: a review [0.03%]
尿毒症毒素在肠道菌群异常与慢性肾脏病轴中发挥的促炎作用综述
Anam Liaqat
Anam Liaqat
There is growing evidence that gut-derived metabolites activate specific signaling pathways that lead to renal inflammation and injury, suggesting that the gut-kidney axis plays a significant role in the inflammatory processes that underlie...
Myeloperoxidase regulates hypoxia-induced inflammation and oxidative stress in liver-spleen axis [0.03%]
髓过氧化物酶调节肝-脾轴低氧诱导的炎症和氧化应激反应
Yonggui Li,Xiaoli Liu,Lingming Zhang et al.
Yonggui Li et al.
Background: High-altitude hypobaric hypoxia induces inflammation and oxidative stress, yet the role of myeloperoxidase (MPO) in this pathology remains incompletely understood. This study aimed to investigate whether MPO m...
Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast [0.03%]
_RESOLUTION_D1通过非TGF-β依赖途径抑制衰老相关分泌表型独立于心脏成纤维细胞分化为肌成纤维细胞
Mauricio Román,José Miguel Osorio,Claudio Espinoza-Pérez et al.
Mauricio Román et al.
Dihydromyricetin exerts neuroprotective effects in acute spinal cord injury by inhibiting NLRP3/Caspase-1 inflammasome through gut microbiome modeling [0.03%]
二氢杨梅素通过重塑肠道菌群抑制NLRP3/Caspase-1炎症小体在急性脊髓损伤中发挥神经保护作用
Yi Yang,Chao Kang,Rizhao Pang et al.
Yi Yang et al.
WWC1 deficiency exacerbates sepsis-induced lung injury by promoting NETosis, M1 and M2b macrophage recruitment, and pyroptosis via YAP1 and STING pathways [0.03%]
WWC1通过YAP1和STING通路促进NETosis、M1和M2b型巨噬细胞募集及pyroptosis从而加剧脓毒症诱导的肺损伤
Yifeng Chen,Han Xu,Chengyang He et al.
Yifeng Chen et al.
Hypoxia synergizes cGAS-STING activation and AKT1 phosphorylation to drive pulmonary inflammation in one-lung ventilation: therapeutic attenuation by RU.521 and MK2206 [0.03%]
缺氧通过cGAS-STING活化和AKT1磷酸化驱动单肺通气的肺部炎症：RU.521和MK2206的治疗作用
Jiangsheng Zhang,Yuntao Zou,Dongni Chen et al.
Jiangsheng Zhang et al.
Background: To explore the mechanisms involved in hypoxia-induced acute lung injury (ALI) and oxidative stress during one-lung ventilation (OLV) in order to find pharmacological interventions that can attenuate OLV injury...