Locomotor and gait changes in the LPS model of neuroinflammation are correlated with inflammatory cytokines in blood and brain [0.03%]
脂多糖致神经炎症模型中小鼠的运动和步态改变与血液及脑内炎症细胞因子的变化相关性研究
Diogo Carregosa,Natasa Loncarevic-Vasiljkovic,Raquel Feliciano et al.
Diogo Carregosa et al.
Lipopolysaccharide (LPS) challenge in mice has been used to identify the mechanisms and therapeutics for neuroinflammation. In this study, we aimed to comprehensively evaluate the behavioral changes including locomotion, exploration, and me...
Correction: Disulfiram Alleviates Acute Lung Injury and Related Intestinal Mucosal Barrier Impairment by Targeting GSDMD-Dependent Pyroptosis [0.03%]
二硫化物亚砜通过靶向GSDMD依赖性焦亡治疗急性肺损伤和相关肠黏膜屏障损害 Correction:
Jiping Zhao,Hong Wang,Jintao Zhang et al.
Jiping Zhao et al.
Circ_001653 alleviates sepsis associated-acute kidney injury by recruiting BUD13 to regulate KEAP1/NRF2/HO-1 signaling pathway [0.03%]
circ_001653通过招募Bud13调节Keap1/Nrf2/HO-1信号通路来缓解脓毒症相关急性肾损伤
Xinxin Li,Wei Zhou,Jianjun Chen et al.
Xinxin Li et al.
Background: The kidney is exceptionally vulnerable during sepsis, often resulting in sepsis-associated acute kidney injury (SA-AKI), a condition that not only escalates morbidity but also significantly raises sepsis-relat...
Effects of exogenous deoxyribonuclease I in collagen antibody-induced arthritis [0.03%]
外源性脱氧核糖核酸酶I在胶原抗体诱导的关节炎中的作用机制研究
Kristína Macáková,Veronika Borbélyová,Mária Tekeľová et al.
Kristína Macáková et al.
Background: Rheumatoid arthritis (RA) is associated with a high concentration of extracellular DNA (ecDNA). This could be a consequence of the inflammation, but the ecDNA could also be involved in the unknown etiopathogen...
Correction: PKM2/STAT1-mediated PD-L1 upregulation on neutrophils during sepsis promotes neutrophil organ accumulation by serving an anti-apoptotic role [0.03%]
关于纠正PKM2/STAT1介导的中性粒细胞PD-L1在脓毒症中的上调通过发挥抗凋亡作用促进中性粒细胞积聚器官学说
Yinjiaozhi Li,Ruoming Tan,Ranran Li et al.
Yinjiaozhi Li et al.
Sonic Hedgehog reduces inflammatory response, decreases blood-spinal cord barrier permeability, and improves locomotor function recovery in an acute spinal cord injury rat model [0.03%]
Sonic Hedgehog 减少炎症反应、降低血脊髓屏障通透性并改善急性脊髓损伤大鼠模型的运动功能恢复
Mohamed Tail,Hao Zhang,Guoli Zheng et al.
Mohamed Tail et al.
Background: Sonic Hedgehog (Shh), extensively researched for its role in early neurogenesis and brain development, has recently been recognized for its neuroprotective potential following neuronal injuries. This study exa...
The effects of chronic, continuous β-funaltrexamine pre-treatment on lipopolysaccharide-induced inflammation and behavioral deficits in C57BL/6J mice [0.03%]
慢性连续型β-奋乃静治疗对脂多糖致C57BL/6J小鼠炎症及行为缺陷的影响
Karissa Hodge,Daniel J Buck,Subhas Das et al.
Karissa Hodge et al.
Background: Inflammation and neuroinflammation are integral to the progression and severity of many diseases and are strongly associated with cardiovascular disease, cancer, autoimmune disorders, neurodegenerative disease...
Mulberroside A mitigates intervertebral disc degeneration by inhibiting MAPK and modulating Ppar-γ/NF-κB pathways [0.03%]
mulberroside A通过抑制MAPK并调节Ppar-γ/NF-κB信号通路来缓解椎间盘退变
Tao Xu,Hongqi Zhao,Xuan Fang et al.
Tao Xu et al.
Background: Intervertebral disc degeneration (IVDD) is a common spine disease with inflammation as its main pathogenesis. Mulberroside A (MA), isolated from herbal medicine, possesses anti-inflammatory characteristics in ...
MicroRNA mediated suppression of airway lactoperoxidase by TGF-β1 and cigarette smoke promotes airway inflammation [0.03%]
TGF-β1和香烟烟雾通过微小核糖核酸介导抑制支气管型乳过氧化物酶促进支气管炎症反应
Maria J Santiago,Srinivasan Chinnapaiyan,Kingshuk Panda et al.
Maria J Santiago et al.
Transforming Growth Factor Beta1 (TGF-β1) signaling is upregulated in Chronic Obstructive Pulmonary disease (COPD), smokers, and people living with HIV. Cigarette smoking and HIV are also independent risk factors for COPD. Chronic inflamma...
Evidence of aberrant anti-epstein-barr virus antibody response, though no viral reactivation, in people with post-stroke fatigue [0.03%]
证据表明，患有中风后疲劳的人会产生异常的抗EB病毒抗体反应，尽管没有病毒再活化
Isobel C Mouat,Li Zhu,Alperen Aslan et al.
Isobel C Mouat et al.
Background: Fatigue is a common complication of stroke that has a significant impact on quality of life. The biological mechanisms that underly post-stroke fatigue are currently unclear, however, reactivation of latent vi...