Macrophage involvement in idiopathic inflammatory myopathy: pathogenic mechanisms and therapeutic prospects [0.03%]
原发性炎症性肌病中的巨噬细胞作用机制及治疗前景
Ziqi Li,Huan Liu,Qibing Xie et al.
Ziqi Li et al.
Idiopathic inflammatory myopathies are a group of systemic autoimmune diseases characterized by chronic muscle inflammation and diverse clinical manifestations. Macrophages, pivotal components of innate immunity, are implicated in immune re...
Non-ionic surfactant vesicles exert anti-inflammatory effects through inhibition of NFκB [0.03%]
非离子表面活性剂囊泡通过抑制NFκB产生抗炎效应
Jonathan McGahon,Stuart Woods,Riccardo D&#x;Elia et al.
Jonathan McGahon et al.
Inflammation can be an unwanted consequence or cause of debilitating diseases of infectious and non-infectious aetiologies. Current anti-inflammatory medications have several deficiencies including lack of specificity and undesirable side e...
Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes [0.03%]
卡瓦醇通过抑制TLR4/MyD88/NF-кB和NLRP3炎性小体在心肌细胞中缓解LPS诱导的心功能障碍
Lu Xu,Xu Yang,Xiao-Ting Liu et al.
Lu Xu et al.
Background: Sepsis-induced myocardial dysfunction (SIMD) may contribute to the poor prognosis of septic patients. Carvacrol (2-methyl-5-isopropyl phenol), a phenolic monoterpene compound extracted from various aromatic pl...
Unveiling the hidden world of transfer RNA-derived small RNAs in inflammation [0.03%]
炎症中的转移RNA来源的小分子RNA的揭秘研究
Peiru Qiu,Qi Jiang,Haojun Song
Peiru Qiu
Transfer RNA-derived small RNAs (tsRNAs) are a newly discovered class of small noncoding RNAs (sncRNAs) that include tRNA-derived stress-induced RNAs (tiRNAs) and tRNA-derived fragments (tRFs). Following the development of high-throughput s...
Correction: Sodium butyrate alleviates R97-116 peptide-induced myasthenia gravis in mice by improving the gut microbiota and modulating immune response [0.03%]
纠正：钠丁酸通过改善肠道菌群和调节免疫反应来缓解小鼠中的R97-116肽诱导的重症肌无力
Jing Sun,Juanjuan Chen,Qinfang Xie et al.
Jing Sun et al.
Clinical, pharmacology and in vivo studies of QingDai (indigo naturalis) promotes mucosal healing and symptom improvement in ulcerative colitis by regulating the AHR-Th17/Treg pathway [0.03%]
青黛通过调节AHR-Th17/Treg信号通路促进溃疡性结肠炎黏膜愈合及症状改善的临床、药理和动物实验研究
Sizhen Gu,Yan Xue,Xiaowen Liu et al.
Sizhen Gu et al.
Qingdai (QD), derived from various plant sources, is commonly used in traditional Chinese medicine for ulcerative colitis (UC) treatment. However, the clinical efficacy and mechanisms of orally administered QD remain unclear. This study aim...
Hossein Bannazadeh Baghi,Mobina Bayat,Parisa Mehrasa et al.
Hossein Bannazadeh Baghi et al.
Viral infections in humans often cause excessive inflammation. In some viral infections, inflammation can be serious and even fatal, while in other infections it can promote viral clearance. Viruses can escape from the host immune system vi...
Influence and distinctions of particulate matter exposure across varying etiotypes in chronic obstructive pulmonary disease (COPD) mouse model [0.03%]
不同病因类型慢性阻塞性肺疾病小鼠模型中颗粒物暴露的影响及差异性研究
Jung Hur,Chin Kook Rhee,Hyoung Kyu Yoon et al.
Jung Hur et al.
Background: Air pollution, notably particulate matter (PM), significantly impacts chronic respiratory disease such chronic obstructive pulmonary disease (COPD). Although asthma-COPD overlap (ACO), considered one of the CO...
Profile of immune response during nasal challenge with dermatophagoides pteronyssinus in subjects with allergic airway diseases [0.03%]
尘螨鼻腔激发过敏性气道疾病患者免疫反应特征分析
Laura Tamasauskiene,Brigita Gradauskiene
Laura Tamasauskiene
Background: T lymphocyte helper (Th) 2 plays the main role in pathogenesis of allergic airway diseases (AAD). Recent studies showed that interleukin (IL) 33, Th17 and Th22 also may be involved in allergic inflammation. Th...
Transcriptional pathways of terminal differentiation in high- and low-density blood granulocytes in sepsis [0.03%]
脓毒症高、低密度血粒细胞终末分化转录通路分析
Tobias Guenther,Anna Coulibaly,Sonia Y Velásquez et al.
Tobias Guenther et al.
Background: Trauma and infection induce emergency granulopoiesis. Counts of immature granulocytes and transcriptional pathways of terminal granulocytic differentiation in blood are elevated in sepsis but correlate with di...