Yangqi Liu,Zijian Chen,Hanchang Cheng et al.
Yangqi Liu et al.
Several studies have demonstrated that the pulmonary immune response is primarily facilitated by antigen-presenting cells (APCs), and that both professional and non-professional APCs contribute to overall pulmonary immunity. APCs play uniqu...
Exploring the mitigating potential of anthocyanin Malvidin in a mouse model of bleomycin-induced pulmonary fibrosis by inhibiting NLRP3 inflammasome activation and oxidative stress [0.03%]
黄烷素Malvidin在博来霉素诱导的肺纤维化小鼠模型中通过抑制NLRP3炎性体激活和氧化应激发挥保护作用的研究
Dingzi Zhou,Lin Cai,Jie Xu et al.
Dingzi Zhou et al.
Background: Malvidin (MV), an essential anthocyanin, has antioxidant and anti-inflammatory effects that may help treat pulmonary fibrosis (PF), a progressive and occasionally fatal condition characterized by severe lung s...
Semaphorin 7a is protective through immune modulation during acetaminophen-induced liver injury [0.03%]
Semaphorein 7a通过免疫调节在对乙酰氨基酚诱导的肝损伤中起到保护作用
Eilidh J Livingstone,Jennifer A Cartwright,Lara Campana et al.
Eilidh J Livingstone et al.
Background and aim: Acetaminophen (APAP) induced acute liver injury (ALI), the leading cause acute liver failure in the western world, has limited treatment options. APAP toxicity results in massive hepatic necrosis and s...
Prehospital pulse-dose glucocorticoid on index of microvascular resistance in patients with ST-segment elevation myocardial infarction: a sub-study of the PULSE-MI trial [0.03%]
院前脉冲剂量糖皮质激素对ST段抬高型心肌梗死患者微血管阻力指数的影响：PULSE-MI试验的一个附属研究
Jasmine Melissa Marquard,Jacob Lønborg,Laust Emil Roelsgaard Obling et al.
Jasmine Melissa Marquard et al.
Background: Microvascular injury in patients with ST-segment elevation myocardial infarction (STEMI) occurs in up to 50%, yet no therapeutic target exists. Inflammation contributes directly to myocardial damage in STEMI a...
Contribution of brain pericytes to neuroinflammation following repetitive head trauma [0.03%]
反复性头部创伤后脑周细胞对神经炎症的作用
Arianna Cembran,Maxwell Eisenbaum,Daniel Paris et al.
Arianna Cembran et al.
Background: Neuroinflammation is a prominent pathological hallmark of traumatic brain injury (TBI) and glia cells have been widely characterized in the onset or progression of brain inflammation. While an effect of inflam...
Retraction Note: Ginsenoside Rg3 alleviates septic liver injury by regulating the lncRNA TUG1/miR-200c-3p/SIRT1 axis [0.03%]
撤稿说明：人参皂苷Rg3通过调节lncRNA TUG1/miR-200c-3p/SIRT1轴减轻脓毒肝损伤
Pan Wu,Xiao Yu,Yue Peng et al.
Pan Wu et al.
Correction: Sodium pyruvate exerts protective effects against cigarette smoke extract-induced ferroptosis in alveolar and bronchial epithelial cells through the GPX4/Nrf2 axis [0.03%]
纠正：钠丙酮酸通过GPX4/Nrf2轴对烟雾提取物诱导的肺泡和支气管上皮细胞铁死亡发挥保护作用
Ziwen Zhao,Zhao Xu,Jingwen Chang et al.
Ziwen Zhao et al.
Unfractionated heparin attenuated histone-induced pulmonary endothelial glycocalyx injury through Ang/Tie2 pathway [0.03%]
肝素通过Ang/Tie2信号通路减轻组蛋白诱导的肺内皮糖萼损伤
Jia Yin,Yawen Chi,Danyan Liu et al.
Jia Yin et al.
Purpose: This study aimed to investigate the involvement of angiopoietin (Ang)/Tie2 pathway in mediating pulmonary endothelial glycocalyx injury in histone-induced acute lung injury in mice, and the protective mechanism o...
Alpha-1 antitrypsin reduces inflammation and vasculopathy in mice with oxygen-induced retinopathy [0.03%]
α-1抗胰蛋白酶减少氧诱导性视网膜病变小鼠的炎症和血管病变
Varaporn Suphapimol,Yu-Han Liu,Sandro Prato et al.
Varaporn Suphapimol et al.
Background: Damage to the retinal vasculature is a major cause of vision loss and is influenced by a pro-inflammatory environment within retinal tissue. Alpha-1 antitrypsin (AAT) is a potent inhibitor of serine proteases ...
Auto-antibodies against carbonyl-modified vimentin in COPD: potential role as a biomarker [0.03%]
抗酒酸基化波形蛋白自身抗体作为COPD生物标志物的潜在作用
L Heinemann,I Adcock,K F Chung et al.
L Heinemann et al.
COPD has many hallmarks of autoimmune dysfunction. Driving this autoimmune response are self-antigens, such as highly abundant structural proteins and cellular proteins, which can lead to the production of auto-antibodies. However, controve...