Organ-specific inflammatory profiles during sepsis: divergent macrophage polarization and oxidative stress response in lung and liver in mouse model of caecal ligation and puncture [0.03%]
腹腔镜下结肠穿孔模型脓毒症时机体器官特异性炎症反应：肺脏及肝脏巨噬细胞极化和氧化应激反应的差异性研究
Aude Bodin,Abdessalem Hammed,Mathieu Magnin et al.
Aude Bodin et al.
Electroacupuncture activates the TET1/PPARα pathway to protect mitochondrial function in MASLD [0.03%]
电针通过激活TET1/PPARα通路保护肝脏线粒体功能防治非酒精性脂肪肝病
Shurui Yang,Yiwen Li,Bowen Lu et al.
Shurui Yang et al.
Ubiquitination-mediated PRDX2 alleviates intervertebral disc degeneration via restraining TBHP-induced nucleus pulposus cell apoptosis, ferroptosis and ECM degradation [0.03%]
泛素化介导的PRDX2通过限制TBHP诱导的髓核细胞凋亡、铁死亡和ECM降解来缓解椎间盘退变
Fanguo Kong,Jiyao Luan,Qipeng Pan et al.
Fanguo Kong et al.
Oral sodium butyrate supplementation acts on intestinal dysbiosis and resolves spinal cord neuroinflammation and nociceptive neuron sensitization [0.03%]
口服丁酸钠补充剂作用于肠道菌群失调，缓解脊髓神经炎症和伤害性感觉神经元敏化
Antimo Fusco,Federica Ricciardi,Michela Perrone et al.
Antimo Fusco et al.
CRSwNP-derived cells retain native disease-relevant characteristics in vitro [0.03%]
CRSwNP来源的细胞在体外保留了其固有的疾病相关特性
Philipp Kühnel,Luisa Vossler,Melanie Siemen et al.
Philipp Kühnel et al.
The ErbB-tyrosine kinase inhibitor, neratinib, has anti-inflammatory effects in multimorbidity by increasing macrophage efferocytosis via the upregulation of MerTK [0.03%]
ErbB-酪氨酸激酶抑制剂奈拉替尼通过上调MerTK促进巨噬细胞炎性吞噬，从而在多病共存时发挥抗炎作用
Kieran A Bowden,Carl Wright,Susan Clark et al.
Kieran A Bowden et al.
TCF4 contributes to OA progression by regulating the transcription of LOXL1 [0.03%]
TCF4通过调节LOXL1转录影响骨关节炎进展
Jiquan Wang,Xiaojun Liu,Xinyi Fan et al.
Jiquan Wang et al.
Activated platelets promote endothelial dysfunction and monocyte recruitment in early renal microvascular injury [0.03%]
活化的血小板通过促进内皮功能障碍和单核细胞募集来加重早期肾微血管损伤
Ukhti Jamil Rustiasari,Melissa Uil,Xiaomeng Zhang et al.
Ukhti Jamil Rustiasari et al.
Chronic kidney disease (CKD) is characterized not only by progressive fibrosis but also by systemic endothelial dysfunction and inflammation. Platelets, traditionally recognized for their role in hemostasis, also serve as key modulators of ...
Resolvin D1 alleviates liver inflammation and fibrosis through SIRT1-mediated NF-κB and TGF-β1/Smads pathways [0.03%]
白细胞介素D1通过SIRT1介导的NF-κB和TGF-β1/Smads信号通路改善肝炎和纤维化
Jiahuan Li,Lingfeng Zhao,Yuwen Xi et al.
Jiahuan Li et al.
Quercetin-loaded silicon dioxide-graphene nanoparticles promotes M2 macrophage reprogramming in mycoplasma-induced pneumonia [0.03%]
负载檞皮素的二氧化硅-石墨烯纳米颗粒通过调节M2型巨噬细胞促进肺炎支原体诱导的小鼠肺炎的治疗
Xiuxiu Liu,Xiufeng Chen,Yonghong Jiang et al.
Xiuxiu Liu et al.
Objective: To develop and evaluate a quercetin-loaded silicon dioxide-graphene nanocomposite (Que@SiO₂-GNPs) for targeted macrophage modulation and epithelial protection in a Mycoplasma-induced pneumonia model. ...