Dietary plant polysaccharides as modulators of brain aging: mechanistic links to inflammaging, the gut brain axis and amyloid tau pathology [0.03%]
膳食植物多糖作为调节大脑衰老的因子：其作用机制与低度炎症、肠脑轴及淀粉样蛋白Tau病理之间的联系
Vishal S Bagul,Rakesh E Mutha
Vishal S Bagul
Objectives: This review critically evaluates chemically characterized plant-derived polysaccharides (PS) as dietary modulators of brain aging, focusing on their structural features, gut-brain mechanisms and effects on neuroinflammation, amy...
Folic acid ameliorates myelination deficits and cognitive-emotional impairments in offspring of advanced maternal age [0.03%]
叶酸改善高龄产妇后代的髓鞘形成缺陷和认知-情绪障碍
Xinru Yan,Chunxue Jiang,Zhijia Lv et al.
Xinru Yan et al.
Advanced maternal age (AMA), defined as pregnancy at 35 years of age or older, has been associated with adverse neurodevelopmental outcomes in offspring. However, its long-term effects and underlying mechanisms remain incompletely understoo...
Efficacy of prebiotics, probiotics, and postbiotics on depression: a systematic review and meta-analysis of randomized controlled trials [0.03%]
益生元、益生菌和后生素对抑郁症疗效的系统评价和meta分析
Nazia Anjum,Zaheer Ahmed,Fouzia Anjum et al.
Nazia Anjum et al.
Background: Depression is a global health issue linked to gut-microbiota-dysbiosis, which influences brain function through the gut-brain axis. Dietary biotics offer a promising therapeutic avenue. ...
The impact of supplements on cognitive function for Alzheimer's disease or mild cognitive impairment: a systematic review and network meta-analysis [0.03%]
补充剂对阿尔茨海默病或轻度认知障碍的认知功能的影响：系统评价和网络meta分析
Yafang Li,Qi Leng,Yunyun Wang
Yafang Li
Objective: Global aging is increasing the incidence of Alzheimer's disease (AD) and mild cognitive impairment (MCI). This network meta-analysis evaluates the effects of dietary supplements on cognitive function in AD/MCI ...
Modulatory effects of hesperidin on rotenone-induced neurotoxicity in Drosophila melanogaster [0.03%]
芸香苷通过调节线粒体动态平衡缓解鱼藤酮诱发的果蝇神经毒性损伤作用
Iqra Subhan,Yasir Hasan Siddique
Iqra Subhan
Neurodegenerative disorders are closely associated with oxidative stress, mitochondrial dysfunction, and apoptosis. Rotenone, a potent inhibitor of mitochondrial complex I, is widely used to model Parkinson-like pathology because it induces...
S-allyl cysteine suppresses lipopolysaccharide-induced microglial inflammation accompanied by attenuation of JNK1/2 and STAT3 signaling [0.03%]
S-烯丙基半胱氨酸通过抑制JNK1/2和STAT3信号通路减弱脂多糖引起的微胶质细胞炎症反应
Ryoji Eguchi,Ayaka Ishida,Toshiko Suzuki-Yamamoto et al.
Ryoji Eguchi et al.
Background: S-allyl-L-cysteine (SAC) is a garlic-derived organosulfur compound with reported anti-inflammatory properties. SAC has been detected in the brain after oral administration in animal studies, suggesting relevan...
Integrated analysis of nutrition profiles and dried blood spot proteomics reveals patterns associated with autism spectrum disorder [0.03%]
营养状况和干血斑蛋白组学的综合分析揭示了自闭症谱系障碍的相关模式
Hoshik Kwon,Su-In Yoon,Sooyeon Baek et al.
Hoshik Kwon et al.
Objectives: To investigate whether dietary behavior-derived nutritional profiles and proteomic analysis of dried blood spots (DBS) could identify patterns associated with autism spectrum disorder (ASD). ...
Association between ultra-processed food intake, depression risk and quality of life in community-dwelling older adults [0.03%]
社区老年人摄入超加工食品与抑郁风险和生活质量之间的关系
Jamal Hallajzadeh,Parasto Yousefi Tanha,Arian Azadnia et al.
Jamal Hallajzadeh et al.
Background: This investigation aimed to evaluate the relationship between ultra-processed foods (UPFs) intake and indicators of depression and quality of life (QoL) in community-dwelling older adults.Methods: In this community-based cross-s...
Healthy-Unhealthy food group balance and cognitive performance in Chilean adolescents: a canonical correlation analysis - The Cogni-Action Project [0.03%]
智利青少年健康与不健康食物组平衡与认知表现：典范相关分析——来自Cogni-Action项目的结果
Humberto Peña-Jorquera,Alexis Díaz-Bahamondes,Natalia Quijada-Mateluna et al.
Humberto Peña-Jorquera et al.
Background: While associations between individual nutrients and cognitive performance are well documented, the joint influence of healthy and unhealthy food group combinations on cognition remains poorly understood. This ...
Microbial modulation of CNS remyelination in multiple sclerosis: the missing link in gut-brain axis research [0.03%]
肠道微生物调节中枢神经系统少突胶质细胞髓鞘再生：多发性硬化症脑-肠轴研究中的缺失环节
Mingzhu Li,Peng Sun,Xiaojing Zhou et al.
Mingzhu Li et al.
Multiple sclerosis (MS) is a chronic, immune-mediated disorder of the central nervous system (CNS) marked by demyelination and neurodegeneration. While much attention has focused on immune dysregulation and neuroinflammation, the failure of...