Comparison of concurrent imaging modalities for staging of dogs with appendicular primary bone tumours [0.03%]
用于四肢原发骨肿瘤分期的并发影像学方法比较
M L Oblak,S E Boston,J P Woods et al.
M L Oblak et al.
This study assessed the use of whole body computed tomography (CT) for the evaluation of metastasis in dogs with primary appendicular bone tumours compared to long bone survey radiography, bone scintigraphy and thoracic radiographs. Fifteen...
Peripheral blood abnormalities and bone marrow infiltration in canine large B-cell lymphoma: is there a link? [0.03%]
犬大B细胞淋巴瘤外周血异常和骨髓浸润之间的关系探讨
V Martini,E Melzi,S Comazzi et al.
V Martini et al.
Official guidelines do not consider bone marrow (BM) assessment mandatory in staging canine lymphoma unless blood cytopenias are present. The aim of this study was to find out if blood abnormalities can predict marrow involvement in canine ...
Canine oral fibrosarcomas: a retrospective analysis of 65 cases (1998-2010) [0.03%]
犬口腔纤维肉瘤：1998-2010年65例回顾性分析
H Gardner,J Fidel,G Haldorson et al.
H Gardner et al.
The objective of this retrospective study was to report the outcome of treatment of canine oral fibrosarcomas (FSA) in relation to median survival and progression-free survival (PFS), and to report whether grade was prognostic in relation t...
Biological behaviour of canine mandibular osteosarcoma. A retrospective study of 50 cases (1999-2007) [0.03%]
犬下颌骨肉瘤的生物学行为研究（1999-2007）回顾性分析50例
V J Coyle,K M Rassnick,L B Borst et al.
V J Coyle et al.
The purpose of this retrospective study was to describe the biological behaviour of canine mandibular osteosarcoma (OSA) and to examine factors for their impact on metastasis-free interval (MFI) and survival time (ST). Records from dogs tre...
Identification and evaluation of putative tumour-initiating cells in canine malignant melanoma cell lines [0.03%]
犬恶性黑色素瘤细胞系中肿瘤启动细胞的鉴定和评估
H M Wilson-Robles,M Daly,C Pfent et al.
H M Wilson-Robles et al.
Tumour-initiating cells (TICs) have been identified in many solid human tumours, including malignant melanoma. In this study, an enriched TIC population was identified in two canine malignant melanoma cell lines (CML1 and CML6M) using cell ...
Canine osteosarcoma cells exhibit resistance to aurora kinase inhibitors [0.03%]
犬成骨肉瘤细胞表现出对aurora激酶抑制剂的耐药性
C M Cannon,J Pozniak,M C Scott et al.
C M Cannon et al.
We evaluated the effect of Aurora kinase inhibitors AZD1152 and VX680 on canine osteosarcoma cells. Cytotoxicity was seen in all four cell lines; however, half-maximal inhibitory concentrations were significantly higher than in human leukae...
Serial evaluation of neutrophil function in tumour-bearing dogs undergoing chemotherapy [0.03%]
肿瘤负载的狗进行化疗过程中嗜中性粒细胞功能的连续评估
A K LeBlanc,C J LeBlanc,B W Rohrbach et al.
A K LeBlanc et al.
We hypothesized that neutrophil function in tumour-bearing dogs is negatively impacted by chemotherapy. Flow cytometric techniques were used to assess neutrophil oxidative burst and phagocytic activities at baseline, 7 and 21 days after ind...
F Rossi,L Aresu,M Vignoli et al.
F Rossi et al.
The aim of this retrospective study was to describe clinical features, treatment and outcome of 21 dogs with metastatic cancer of unknown primary (MCUP), a biopsy-proven malignancy being diagnosed at a metastatic stage, in which the anatomi...
The value of molecular expression of KIT and KIT ligand analysed using real-time polymerase chain reaction and immunohistochemistry as a prognostic indicator for canine cutaneous mast cell tumours [0.03%]
采用实时聚合酶链反应和免疫组化分析KIT及KIT配体分子表达的价值作为犬皮肤肥大细胞瘤预后的指标
T A Costa Casagrande,L M de Oliveira Barros,H Fukumasu et al.
T A Costa Casagrande et al.
This study investigated the correlation between KIT gene expression determined by immunohistochemistry and real-time polymerase chain reaction (RT-PCR) and the rate of tumour recurrence and tumour-related deaths in dogs affected with mast c...
Development of an ELISA to detect circulating anti-asparaginase antibodies in dogs with lymphoid neoplasia treated with Escherichia coli l-asparaginase [0.03%]
一种检测爱德华沙门菌天冬酰胺酶抗体的ELISA的开发用于诊断淋巴肿瘤并监测治疗效果
J A Kidd,P Ross,A S Buntzman et al.
J A Kidd et al.
Resistance to Escherichia coli l-asparaginase in canine lymphoma occurs frequently with repeated administration, a phenomenon often attributed, without substantiation, to the induction of neutralizing antibodies. To test the hypothesis that...