CT-Based Radiomic Features Predict Cervical Lymph Node Metastasis in Dogs With Oral Malignancy: A Machine Learning Study Using Leave-One-Patient-Out Cross-Validation [0.03%]
基于CT的影像组学特征预测口腔恶性肿瘤犬头颈部淋巴结转移：一种利用交叉验证的机器学习方法
Christopher J Pinard,Andrew Lagree,Ryan Appleby et al.
Christopher J Pinard et al.
Accurate preoperative identification of cervical lymph node (LN) metastasis is essential for staging and treatment planning in dogs with oral malignancy, yet conventional imaging offers limited diagnostic sensitivity. This retrospective stu...
Safety and Feasibility of Infusing Ex Vivo Expanded Allogeneic Canine Natural Killer Cells for the Treatment of Metastatic Solid Tumours [0.03%]
体外扩增的同种异体犬天然杀伤细胞治疗转移性实体瘤的安全性和可行性研究
Allison M Weisnicht,Fernanda Szewc,Monica Moonkyung Cho et al.
Allison M Weisnicht et al.
Companion canines need advances in therapeutic options for solid tumour malignancies. Natural killer (NK) cell infusions offer a promising treatment modality in canines with solid tumours. Autologous natural killer products are limited by d...
Enhancing EGFR Inhibition: Monensin and Erlotinib Synergize to Eliminate Cancer Stem Cells in Canine Mammary Tumours [0.03%]
增强EGFR抑制作用：单霉素和厄洛替尼协同消除犬乳癌干细胞
Tian Fang,Mengxing Zhang,Chang Ma et al.
Tian Fang et al.
Canine mammary tumours (CMTs) and human breast cancer (HBC) share highly similar pathological characteristics. Cancer stem cells (CSCs) are critical to breast cancer invasion, metastasis, drug resistance, and recurrence. The experiment util...
Sentinel Lymph Node Mapping Identifies Variable Cervical Drainage and Metastatic Nodes Outside Traditional Sampling Sites in Canine Oromaxillofacial Tumours [0.03%]
哨兵淋巴结显像可识别犬口腔颌面部肿瘤变异性颈淋巴引流及传统取样部位外的转移淋巴结
Emilia Chrostek,Jessica Lawrence,Boaz Arzi et al.
Emilia Chrostek et al.
Sentinel lymph node mapping (SLNM) has emerged as a key technique to guide decisions regarding nodal extirpation in dogs with oromaxillofacial tumours. The primary aims of this retrospective study were to describe the clinical utility of in...
Comparison of Aerosolised and Traditional Tumour Margin Inking: A Prospective Blinded Histopathological Review in Canine Skin Tumours [0.03%]
犬皮肤肿瘤气溶胶和传统涂色组织学分析的比较研究
Kaida L Wouters,Sam R Snelling,John M Morton et al.
Kaida L Wouters et al.
Inking of canine skin tumours facilitates histopathological margin assessment. While traditional dab application is standard practice, aerosolised (spray) application may offer practical advantages. The objective of this study was to determ...
Surgery and Adjuvant Electrochemotherapy Compared to Surgery Alone for Treatment of Canine Incompletely Excised Soft Tissue Sarcomas [0.03%]
与单独手术相比，外科手术联合辅助电化学疗法治疗未能完全切除的犬软组织肉瘤的效果研究
Ramos Sofia,Macfarlane Michael,Polton Gerry et al.
Ramos Sofia et al.
The predominant challenge in canine soft tissue sarcomas (STSs) is achieving local tumour control, for which surgical excision remains the standard treatment. When complete margins are not attainable, adjuvant therapy may be recommended. El...
Anti-Canine Mammary Carcinoma Effects of mPP-Based Nano-Micelles Encapsulating DPIA [0.03%]
基于mPP的纳米胶束载DPIA抗犬乳腺癌效应
Yuhong Chen,Han Wang,Zhenyu Wang et al.
Yuhong Chen et al.
Triple negative breast cancer (TNBC) presents a significant challenge in breast cancer treatment. Canine mammary carcinoma, characterized by spontaneous tumours in female dogs, serves as a robust spontaneous model for TNBC. In this study, D...
Long-Term Outcome of Electrochemotherapy in the Treatment of Advanced Stages (T3-T4) of Feline Nasal Planum Squamous Cell Carcinoma [0.03%]
电化学疗法治疗猫鼻平面鳞状细胞癌(T3-T4期)的长期疗效评估
Delia Franchini,Ilaria Laino,Chiara Perrone et al.
Delia Franchini et al.
Electrochemotherapy is increasingly used as a locoregional treatment for feline squamous cell carcinoma, but its role in advanced nasal planum disease remains poorly defined. This retrospective study evaluated the long-term outcome of ECT a...
Transcriptomic and microRNA Profiling Suggest a Candidate RIPPLY1-cfa-miR-187 Relationship in Canine Mammary Gland Tumours From Dogs With Confirmed Metastasis [0.03%]
转录组和微小RNAs特征分析揭示了犬乳头状肿瘤中具有转移性的RIPPLY1-cfa-miR-187关系候选人
Shaohsu Wang,Masashi Takahashi,Hui-Wen Chen et al.
Shaohsu Wang et al.
Canine mammary gland tumours (MGT) represent a common malignancy in intact female dogs, with a high metastasis rate approaching 50% and a poor prognosis. However, metastasis-related genes remain largely unelucidated. Accordingly, we aimed t...
Raman Spectroscopy for Differentiating High- and Low-Grade Canine Cutaneous Mast Cell Tumours [0.03%]
拉曼光谱区分犬皮肤高、低恶性度肥大细胞瘤的研究
José Catarino,Susana Silva,Susana Novais et al.
José Catarino et al.
Canine cutaneous mast cell tumours (MCTs) demonstrate variable clinical behaviour. Histological grading remains the primary prognostic approach, but some low-grade tumours behave aggressively, and interobserver variability persists. This un...