Analysis of genomic mutation and immunohistochemistry of platelet-derived growth factor receptors in canine vascular tumours [0.03%]
犬血管肿瘤血小板衍生生长因子受体基因组突变及免疫组织化学分析
S Abou Asa,T Mori,K Maruo et al.
S Abou Asa et al.
We examined whether mutation of the platelet-derived growth factor receptor protein tyrosine kinase (PDGFR)-α and PDGFR-β genes contributes to their overexpression in canine vascular tumours. Genomic sequences of trans- or juxtamembrane r...
Response evaluation criteria for solid tumours in dogs (v1.0): a Veterinary Cooperative Oncology Group (VCOG) consensus document [0.03%]
犬实体瘤疗效评价标准（版本1.0）：兽医合作肿瘤学组共识文件
S M Nguyen,D H Thamm,D M Vail et al.
S M Nguyen et al.
In veterinary medical oncology, there is currently no standardized protocol for assessing response to therapy in solid tumours. The lack of such a formalized guideline makes it challenging to critically compare outcome measures across vario...
Identification of novel tumour-associated antigens in canine mammary gland tumour [0.03%]
犬乳腺肿瘤相关新抗原的鉴定
M Furuya,M Funasaki,H Tani et al.
M Furuya et al.
Canine mammary gland tumour (MGT) is the most common neoplasm in female dogs and has similar biological characteristics to human MGT. Spontaneous canine MGT is a more attractive clinical model in oncological research than that of the murine...
Comparative Study
Veterinary and comparative oncology. 2015 Sep;13(3):194-202. DOI:10.1111/vco.12034 2015
Expression and functionality of TRPV1 receptor in human MCF-7 and canine CF.41 cells [0.03%]
人MCF-7和犬CF.41细胞中TRPV1受体的表达及功能研究
C Vercelli,R Barbero,B Cuniberti et al.
C Vercelli et al.
As canine mammary tumours (CMT) and human breast cancer share clinical and prognostic features, the former have been proposed as a model to study carcinogenesis and improved therapeutic treatment in human breast cancer. In recent years, it ...
Canine osteosarcoma cell lines from patients with differing serum alkaline phosphatase concentrations display no behavioural differences in vitro [0.03%]
不同血清碱性磷酸酶浓度患者来源的骨肉瘤细胞系在体外无行为差异
K E Holmes,V Thompson,C M Piskun et al.
K E Holmes et al.
Osteosarcoma is an aggressive malignancy and represents the most frequent primary bone malignancy of dogs and humans. Prognostic factors reported for osteosarcoma include tumour size, presence of metastatic disease and serum alkaline phosph...
Comparison of mitotic index and Ki67 index in the prognostication of canine cutaneous mast cell tumours [0.03%]
犬皮肤肥大细胞瘤预后判断中分裂指数和Ki67指数的比较
D Berlato,S Murphy,P Monti et al.
D Berlato et al.
Proliferation markers are commonly used for prognostication of mast cell tumours. The aim of the study is to compare the relative abilities of Ki67 and mitotic index to predict survival in the same cohort of dogs with cutaneous MCTs. Histol...
Comparative Study
Veterinary and comparative oncology. 2015 Jun;13(2):143-50. DOI:10.1111/vco.12029 2015
S S Withers,E G Johnson,W T N Culp et al.
S S Withers et al.
Paraneoplastic hypertrophic osteopathy (pHO) is known to occur in both canine and human cancer patients. While the pathology of pHO is well-described in the dog, very little information exists regarding the true clinical presentation of dog...
Evaluation of histological grade and histologically tumour-free margins as predictors of local recurrence in completely excised canine mast cell tumours [0.03%]
评价组织学分级和组织学上肿瘤阴性切缘作为完全切除的犬肥大细胞瘤局部复发预测因素的价值
L Donnelly,C Mullin,J Balko et al.
L Donnelly et al.
Completeness of mast cell tumour (MCT) excision is determined by assessment of histologically tumour-free margins (HTFM). The HTFM width necessary to prevent local recurrence (LR), recognized as histologic safety margin (HSM) in human oncol...
Comparison of abdominal ultrasound and magnetic resonance imaging for detection of abdominal lymphadenopathy in dogs with metastatic apocrine gland adenocarcinoma of the anal sac [0.03%]
对比检查肛周腺癌转移的犬只腹部超声与磁共振成像诊断腹腔淋巴结肿大的效果
C L Anderson,C S MacKay,G D Roberts et al.
C L Anderson et al.
Imaging studies in humans with anal and rectal cancer indicate that magnetic resonance imaging (MRI) is a more sensitive technique than abdominal ultrasound (AUS) for the detection of abdominal lymphadenopathy. The purpose of this retrospec...
Comparative Study
Veterinary and comparative oncology. 2015 Jun;13(2):98-105. DOI:10.1111/vco.12022 2015
A prospective evaluation of the impact of second-opinion histopathology on diagnostic testing, cost and treatment in dogs and cats with cancer [0.03%]
前瞻性评估第二意见病理学对犬猫肿瘤诊断、费用和治疗的影响
R C Regan,K M Rassnick,E K Malone et al.
R C Regan et al.
Second-opinion histopathology is a common practice in human medicine to avoid unnecessary procedures, costs and to optimize therapy. Histopathology review has been recommended in veterinary oncology as well. In this prospective evaluation o...