Serum Lactate Dehydrogenase as a Potential Prognostic Biomarker in Dogs With Appendicular Osteosarcoma [0.03%]
乳酸脱氢酶作为附肢骨肉瘤犬预后生物标志物的潜力
Dina Guerra,Silvia Sabattini,Carmit Chalfon et al.
Dina Guerra et al.
In human medicine, serum lactate dehydrogenase (LDH) is a well-established prognostic marker in osteosarcoma, reflecting tumour burden. This study evaluates serum LDH as a prognostic biomarker in dogs with histologically confirmed appendicu...
Diagnosis and Classification of Primary Nodal Lymphomas in Dogs: A Consensus of the Oncology-Pathology Working Group [0.03%]
犬原发性淋巴结淋巴瘤的诊断与分类：肿瘤病理工作组共识
Michael O Childress,Anne Avery,Erica Behling-Kelly et al.
Michael O Childress et al.
One of the primary objectives of the Oncology Pathology Working Group (OPWG) is for oncologists and pathologists to collaboratively generate consensus documents to standardise aspects of and provide guidelines for oncologic pathology in vet...
Potent Therapeutic Activity of NEO212 in Preclinical Models of Human and Canine Leukaemia and Lymphoma [0.03%]
NEO212在人类和犬科急性白血病与淋巴瘤的临床前模型中的强大治疗活性
Thomas C Chen,Steve Swenson,Thu Zan Thein et al.
Thomas C Chen et al.
Haematological cancer types, such as leukaemia and lymphoma, represent diseases that are life-threatening to canine and human patients alike, and better treatments are needed. We are developing a novel anticancer agent, NEO212, a conjugate ...
Outcome and Prognostic Factors of Dogs Treated for Infiltrative Lipoma Undergoing Radiation Therapy: A Retrospective Multi-Institutional Study of 29 Cases [0.03%]
放疗治疗浸润性脂肪瘤的犬的预后因素及疗效：29例回顾性多机构研究
Arata Matsuyama,Valerie J Poirier,Michelle M Turek et al.
Arata Matsuyama et al.
Canine infiltrative lipomas are localised and invasive tumours that are commonly treated with surgery and/or radiation therapy (RT). There is limited efficacy data for treatment of infiltrative lipomas, and optimal fractionation strategies ...
Impacts of Vincristine and Prednisolone Chemotherapy on the Canine Gut Microbiota in Dogs Undergoing Treatment for Lymphoma [0.03%]
长春新碱和泼尼松治疗对淋巴瘤犬的肠道微生物的影响
Juan Aragon,Annika M Weber,Madison Tipton et al.
Juan Aragon et al.
Chemotherapy can have adverse gastrointestinal effects in dogs and people. The objective of this study was to assess the impact of vincristine and prednisolone/prednisone, as part of a CHOP chemotherapy [cyclophosphamide, hydroxydaunorubici...
Expanding the Spectrum of Canine Diffuse Large B-Cell Lymphoma Genetic Aberrations Through Whole Genome Sequencing Analysis [0.03%]
通过全基因组测序分析扩展犬型弥漫性大B细胞淋巴瘤遗传异常的范围
Antonella Fanelli,Eugenio Mazzone,Diana Giannuzzi et al.
Antonella Fanelli et al.
Diffuse large B-cell lymphoma (DLBCL) is one of the most prevalent haematological malignancies in both humans and dogs, characterised in both species by significant clinical heterogeneity and limited prognostic predictability. With the intr...
Neurological Recovery in 14 Cats With Epidural Lymphoma Treated With Chemotherapy [0.03%]
接受化疗的14只猫患硬膜外淋巴瘤后的神经恢复效果
Julya Nathalya Felix Chaves,Mathias Reginatto Wrzesinski,Julia da Silva Rauber et al.
Julya Nathalya Felix Chaves et al.
The purpose of this study was to evaluate the rate and timing of neurological recovery in cats with epidural lymphoma who were treated with chemotherapy. The study included cats with various degrees of neurological impairment, confirmed dia...
Vinorelbine as a Rescue Treatment for Canine Histiocytic Sarcoma: A Multicentre Retrospective Study of 18 Dogs [0.03%]
vinorelbine救治犬郎格汉斯组织细胞增生症/郎格汉斯基瘤的多中心回顾性研究（18例）
Nina Vigevani,Carmit Chalfon,Alexandra Guillén et al.
Nina Vigevani et al.
Histiocytic sarcoma (HS) is a highly metastatic cancer, and while response to several chemotherapy agents has been studied, the outcome remains poor. Vinorelbine (VNB) has been considered a possible treatment option, but data are limited. T...
Evaluation of Serum Level of Chemokine (C-C Motif) Ligand 2 (CCL2) in Canine Urothelial Carcinomas, Mast Cell Tumours, and Insulinomas, and Its Correlation With Circulating Monocytes [0.03%]
评估犬尿路上皮癌、肥大细胞肿瘤和胰岛素瘤中细胞趋化因子(CC基序)配体2(CCL2)的血清水平及其与循环单核细胞的相关性
Naomi Shimizu,Annick Hamaide,Stéphanie Noël et al.
Naomi Shimizu et al.
Chemokine (C-C motif) ligand 2 (CCL2) is a strong monocyte chemoattractant that has been shown to be increased in humans and dogs with neoplasia. Although in human urothelial carcinoma (UCa) CCL2 levels increase with metastatic disease, a p...
Auranofin Induces ER Stress-Mediated Apoptosis, and Its Combination With Bortezomib Elicits Paraptosis-Like Cell Death in Malignant Canine Mammary Tumour Cells [0.03%]
金诺芬诱导内质网应激介导的细胞凋亡及其与硼替佐米联合用药引起恶性犬乳腺肿瘤细胞类-paraptosis细胞死亡
Yoon-Ho Suh,Se-Hoon Kim,Ki-Hoon Song et al.
Yoon-Ho Suh et al.
Canine mammary tumours (CMT) are common in female dogs, often associated with malignancy and limited responses to conventional therapies. This study explores the potential of Auranofin (AF) in malignant CMT, focusing on its ability to induc...