Andrew D Yale,Asia L Crawford,Irina Gramer et al.
Andrew D Yale et al.
Large granular lymphocyte lymphoma (LGLL) is a rare form of lymphoma in dogs. Limited information exists regarding presentation, treatment response, and outcome. The aim of this single-institute, retrospective study was to characterise clin...
Treatment of feline intermediate to high-grade alimentary lymphoma: A retrospective evaluation of 55 cats treated with the VAPC combination chemotherapy protocol (2017-2021) [0.03%]
猫中度至高度胃肠淋巴瘤的治疗：回顾性评估使用VAPC联合化疗方案治疗的55只猫(2017-2021年)
Antony Stewart Moore,Angela Erica Frimberger
Antony Stewart Moore
The most commonly utilized protocols to treat lymphoma in cats employ vincristine, cyclophosphamide and prednisone; with additional drugs sometimes used including L-asparaginase and doxorubicin. Medical records were reviewed for 55 cats wit...
Evaluation of the health-related quality of life in dogs following intracranial meningioma resection using a specifically developed questionnaire [0.03%]
使用特定开发的问卷评估脑内膜瘤切除术后狗的生活质量相关健康状况
Chiara Köcher,Alexander Tichy,Gabriele Gradner
Chiara Köcher
As advanced treatments are becoming increasingly feasible in veterinary medicine, the evaluation of the health-related quality of life (HRQOL) of treated animals is becoming more relevant. We evaluated owner-perceived HRQOL of 10 dogs that ...
Elevated expression of miR-301a and its functional roles in canine oral melanoma [0.03%]
犬口腔黑色素瘤中miR-301a的高表达及其功能作用
Md Nazmul Hasan,Md Mahfuzur Rahman,Al Asmaul Husna et al.
Md Nazmul Hasan et al.
miR-301a is one of numerous dysregulated microRNAs (miRNAs) in canine oral melanoma (COM), one of which is miR-301a (upregulated). Its biological role has been described in various human cancer types, including malignant melanoma, but not i...
Dysregulated miRNAs in a canine model of haemangiosarcoma metastatic to the brain [0.03%]
一种犬类血管肉瘤脑转移模型中的异常miRNA表达模式研究
Silvia Sabattini,Vito Antonio Baldassarro,Riccardo Zaccone et al.
Silvia Sabattini et al.
Haemangiosarcoma is a highly metastatic and lethal cancer of blood vessel-forming cells that commonly spreads to the brain in both humans and dogs. Dysregulations in phosphatase and tensin (PTEN) homologue have been identified in various ty...
Homoharringtonine induces apoptosis of mammary carcinoma cells by inhibiting the AKT/mTOR signaling pathway [0.03%]
霍康宁通过抑制AKT/m TOR信号通路诱导乳腺癌细胞的凋亡
Xue Zhang,Chen Mei,Zhixuan Liang et al.
Xue Zhang et al.
Mammary tumour is the most common type of tumour in dogs, especially in unneutered female dogs. Homoharringtonine (HHT) is a natural alkaloid that can be used to treat various types of human tumour. However, the inhibitory effect and mechan...
Genomic analysis across 53 canine cancer types reveals novel mutations and high clinical actionability potential [0.03%]
基于53种犬类癌症的基因组分析揭示了新的突变及高度临床应用潜能
Sharadha Sakthikumar,Manisha Warrier,Derick Whitley et al.
Sharadha Sakthikumar et al.
A genomic understanding of the oncogenic processes and individual variability of human cancer has steadily fueled improvement in patient outcomes over the past 20 years. Mutations within tumour tissues are routinely assessed through clinica...
Comparison of the anticancer effects of various statins on canine oral melanoma cells [0.03%]
几种他汀类药物对犬口腔黑色素瘤细胞抗肿瘤效果的比较研究
Takuro Ishikawa,Nanami Irie,Jiro Tashiro et al.
Takuro Ishikawa et al.
Canine oral melanoma is a highly malignant cancer with a poor prognosis. Statins, commonly used drugs for treating dyslipidemia, exhibit pleiotropic anticancer effects and marked anti-proliferative effects against melanoma cells. The antica...
Correlation between computed tomography and histological evaluation of nodal metastasis in dogs with mast cell tumours [0.03%]
犬mast细胞肿瘤淋巴结转移的CT和病理评估相关性研究
Hiroshi Miyagi,Katy L Townsend,Alyssa Michael Ettinger et al.
Hiroshi Miyagi et al.
Early diagnosis of nodal metastasis has been shown to impact prognosis for dogs with mast cell tumours (MCT). The objective of this retrospective study was to determine the correlation between computed tomographic characteristics of lymph n...
Spotlight on capecitabine for the treatment of unresectable or metastatic carcinoma of various origin: A retrospective study of 25 dogs [0.03%]
卡培他滨治疗不可切除或转移性各种来源的癌的回顾性研究——25例犬临床疗效观察
Chiara Agnoli,Sofia Rimondi,Giulia Ghisoni et al.
Chiara Agnoli et al.
Capecitabine, the oral prodrug of 5-fluorouracil, is indicated in people to treat various malignant epithelial cancers. In dogs, capecitabine has not been extensively evaluated. The aim of this retrospective study was to investigate toxicit...