Retrospective evaluation of toceranib phosphate (Palladia) in the treatment of canine carcinomatosis and mesothelioma [0.03%]
他克莫司磷酸盐（帕拉达）治疗犬癌和间皮瘤的回顾性评价
Kelly A Hicks,Haley J Leeper,Kaitlin M Curran
Kelly A Hicks
Canine carcinomatosis (CC) and mesothelioma (CM) are rare but aggressive neoplasms that historically have been associated with poor prognoses. There is limited information regarding treatment for CC and CM. The purpose of this retrospective...
Alternating rabacfosadine and doxorubicin for treatment of naïve canine lymphoma [0.03%]
替拉福沙丁与多柔比星交替治疗未接受过治疗的犬淋巴瘤
Corey F Saba,Timothy M Fan,Brenda S Phillips et al.
Corey F Saba et al.
The current standard of care treatment for canine lymphoma is a multi-agent, CHOP-based chemotherapy protocol. Single agent doxorubicin (DOX) is less burdensome; however, multi-agent chemotherapy protocols are often superior. The recently a...
Investigation of efficacy of two different chemotherapy protocols used in neoadjuvant chemotherapy in clinical stages II-IV canine malignant mammary tumours [0.03%]
两种新辅助化疗方案对临床二期至四期犬恶性乳腺肿瘤疗效的评估研究
Fikriye Ecem Kuruoglu,Zeynep Merve Ekici,Deniz Nak et al.
Fikriye Ecem Kuruoglu et al.
The first aim of this study is to demonstrate the clinical efficacy and reliability of two different neoadjuvant chemotherapy (NAC) protocols consisting of doxorubicin/cyclophosphamide (AC) and paclitaxel in dogs with clinical stages II-IV ...
Radiation toxicity grading after chemoradiotherapy of canine urinary tract carcinomas: Comparing VRTOG to VRTOG_v2.0 [0.03%]
放化疗后根据VRTOG和VRTOG_v2.0分级的犬泌尿道癌放射毒性反应分级
Carlotta Ahrens,Laura Beatrice,Valeria Meier et al.
Carlotta Ahrens et al.
Radiation toxicities may be underestimated after treatment of transitional cell carcinoma in dogs' lower urinary tract. Assessing acute and late toxicities and differentiating them from progressive disease (PD) impacts further therapeutic a...
Effects of trastuzumab emtansine on canine urothelial carcinoma cells in vitro and in vivo [0.03%]
曲妥珠单抗-美坦辛对犬尿路上皮癌细胞的体内外作用研究
Kosei Sakai,Daiki Kato,Junka Yoshinaka et al.
Kosei Sakai et al.
Urothelial carcinoma (UC) is the most common malignancy of the urinary tract in dogs and has aggressive behaviour. Although human epidermal growth factor receptor 2 (HER2) is a known therapeutic target with evidence in canine UC, the effica...
Sodium iodide symporter immunolabelling as a predictor of clinical iodide uptake in canine thyroid carcinoma: A preliminary study [0.03%]
犬甲状腺癌中钠碘转运蛋白免疫组化染色作为临床碘摄取预测指标的初步研究
Katelin V Dark,Owen T Skinner,Dae Young Kim et al.
Katelin V Dark et al.
Thyroid follicular tumours may take up iodide via the sodium-iodide symporter. Knowledge of iodide uptake could then allow treatment with I-131 in dogs with high-risk tumours. The objective of this study was to determine the relationship be...
The role of companion animal models in radiopharmaceutical development and translation [0.03%]
伴侣动物模型在放射药物研发和转化中的作用
Charles A Maitz,Jeffrey N Bryan
Charles A Maitz
Advancements in molecular imaging and drug targeting have created a renaissance in the development of radiopharmaceuticals for therapy and theranostics. While some radiopharmaceuticals, such as Na[131I]I, have been used clinically for decad...
Urinary and household chemical exposures in pet dogs with urothelial cell carcinoma [0.03%]
患尿细胞癌的宠物狗中尿液和家庭化学物质暴露情况研究
Samantha L Braman,Hannah Peterson,Amy Elbe et al.
Samantha L Braman et al.
Urothelial cell carcinoma (UCC) has been linked to environmental chemical exposures in people, but these risk factors are not well understood in dogs with UCC. We hypothesised that household chemical exposures contribute to the risk of UCC ...
Expression of mPGES1 and p16 in feline and human oral squamous cell carcinoma: A comparative oncology approach [0.03%]
猫和人口腔鳞状细胞癌中mPGES1和p16的表达：一种比较肿瘤学方法
Walaa Hamed Shaker Nasry,Kathleen Jones,Juan Carlos Rodriguez-Lecompte et al.
Walaa Hamed Shaker Nasry et al.
Comparative cancer studies help us determine if discoveries in one species apply to another. Feline and human oral squamous cell carcinoma (FOSCC and HOSCC) are invasive tumours in which inflammation and abnormal p16 expression are reported...
Comparative Study
Veterinary and comparative oncology. 2024 Jun;22(2):204-216. DOI:10.1111/vco.12967 2024
Feline high-grade and large granular lymphocyte alimentary lymphomas treated with COP- or CHOP-based chemotherapy: A multi-centric retrospective study of 57 cases [0.03%]
采用以COP或CHOP方案为基础的化疗治疗猫高级别及大颗粒淋巴细胞消化道淋巴瘤：一项对57例病例的多中心回顾性研究
Grégoire Bernardo Marques,Frédérique Ponce,Claire Beaudu-Lange et al.
Grégoire Bernardo Marques et al.
Specific data regarding outcome of cats with high-grade and large granular lymphocyte alimentary lymphoma (HGAL and LGL, respectively) treated with multi-agent chemotherapy are scarce. The aims of this multi-centric, retrospective study wer...
Multicenter Study
Veterinary and comparative oncology. 2024 Jun;22(2):186-197. DOI:10.1111/vco.12965 2024