Correction: Steroid receptor coactivator-1 facilitates METTL3-mediated m6A modification by coactivating NF-κB and promotes the malignant progression of glioblastoma [0.03%]
订正:类固醇受体共激活物-1通过共激活NF-κB促进METTL3介导的m6A修饰并促进胶质母细胞瘤恶性进展
Liang Liu,Rui Wang,Ke Cheng et al.
Liang Liu et al.
Published Erratum
Oncogene. 2026 May;45(17):1627-1629. DOI:10.1038/s41388-026-03788-8 2026
Correction to: Targeting Lyn regulates Snail family shuttling and inhibits metastasis [0.03%]
Correction to: 抑制 Lyn 可调控 Snail 家族穿梭并抑制转移
D Thaper,S Vahid,K M Nip et al.
D Thaper et al.
Published Erratum
Oncogene. 2026 May;45(17):1630-1631. DOI:10.1038/s41388-026-03789-7 2026
Role of SCAP in regulation of pancreatic homeostasis, pancreatitis, and tumorigenesis [0.03%]
SCAP在胰腺稳态、急性胰腺炎和肿瘤发生中的作用
Anna C Lilly,Valerii A Pavlov,Shabnam Pirestani et al.
Anna C Lilly et al.
Levels of pancreatic ductal adenocarcinoma (PDAC) are increasing, with epidemiological studies nominating obesity, altered cholesterol metabolism, and elevated lipids as risk factors. In prior studies, we determined that elevated expression...
PSPC1-AS2/PSPC1 axis drives STAT3-dependent CCL2 expression to promote M2 macrophage polarization and liver metastasis in gastric cancer [0.03%]
胃癌中PSPC1-AS2/PSPC1轴通过STAT3依赖性诱导CCL2表达促进M2型巨噬细胞极化和肝转移
Yuejiao Zhong,Xuemei Zhou,Yuan Zhou et al.
Yuejiao Zhong et al.
Liver metastasis is a major cause of mortality in gastric cancer (GC), yet the underlying molecular mechanisms remain poorly understood. Long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression and cancer progression...
CSF1R inhibitors mitigate CDK4/6 inhibitor-induced immunosuppression to increase antitumor immunity in HR+/HER2- breast cancer [0.03%]
CSF1R抑制剂可缓解CDK4/6抑制剂引起的免疫抑制,从而提高HR+/HER2-乳腺癌的抗肿瘤免疫力
Siwei Li,Yajie Gong,Hui Li et al.
Siwei Li et al.
Hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR + /HER2 - ) breast cancer, the most common subtype, shows a low pathological complete response (pCR) rate and limited benefit from immunotherapy, highlighting ...
BRD2 is a transcriptional coactivator of Smad3 in mediating TGF-β tumor suppressive responses [0.03%]
BRD2是Smad3转录共激活因子可介导TGF-β的抑癌作用
Shuai Tian,Shuchen Gu,Shuangwu Sun et al.
Shuai Tian et al.
Transforming growth factor-β (TGF-β) is a multifunctional cytokine that regulates cell proliferation, differentiation, migration, and apoptosis. It is generally accepted that TGF-β induces cellular responses through Smad-dependent gene t...
Blocking ubiquitination of hnRNPA1 maintains the self-renewal of breast cancer stem cells via mutually exclusive splicing of PKM pre-mRNA [0.03%]
hnRNPA1蛋白泛素化的阻滞通过PKM前mRNA的排斥性剪接维持乳腺癌干细胞的自我更新能力
Xuemei Lv,Li Han,Wei-Wei Tong et al.
Xuemei Lv et al.
PKM serves as a rate-limiting enzyme in glycolysis, which produces two isoforms depending on the inclusion of either exon 9 (PKM1) or exon 10 (PKM2). The M2 pyruvate kinase (PKM2) isoform is commonly upregulated in various cancers, where it...
GOT1 inhibits hepatocellular carcinoma progression by regulating SLC25A5-dependent mitochondrial apoptosis [0.03%]
GOT1通过调节SLC25A5依赖的线粒体凋亡抑制肝癌进展
Weiwei Zong,Chunxiao Cheng,Yukun Zhang et al.
Weiwei Zong et al.
Hepatocellular carcinoma (HCC), the most common subtype of primary liver cancer, is characterized by a poor prognosis, with most patients diagnosed at advanced stages that are unresectable and resistant to targeted therapies. This underscor...
EGFR ligand Angiogenin predicts response to ALK5 inhibition in pancreatic cancer via a TNF-α paracrine axis in tumor-associated macrophages [0.03%]
EGFR配体血管生成素通过肿瘤相关巨噬细胞的TNF-α旁分泌轴预测胰腺癌对ALK5抑制的反应
Silvia Pietrobono,Veronica De Vita,Domenico Mangiameli et al.
Silvia Pietrobono et al.
Transforming growth factor-β (TGFβ) receptor ALK5 inhibition has shown promise in pancreatic ductal adenocarcinoma (PDAC), but predictive biomarkers remain undefined. We identify angiogenin (ANG) as a negative prognostic yet positive pred...
Dual inhibition of glycolysis and glutaminolysis by targeting FOXO3 for hepatocellular carcinoma treatment [0.03%]
靶向FOXO3抑制糖酵解和谷氨酰胺分解治疗肝细胞癌
Fan Wang,Meng Huang,Kaixuan Sheng et al.
Fan Wang et al.
Metabolic reprogramming is a hallmark of tumorigenesis and progression in hepatocellular carcinoma (HCC) and has emerged as a promising therapeutic strategy. Forkhead box O3 (FOXO3), a critical nuclear transcription factor, is dysregulated ...