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期刊名:Oncogene

缩写:ONCOGENE

ISSN:0950-9232

e-ISSN:1476-5594

IF/分区:7.3/Q1

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Anna C Lilly,Valerii A Pavlov,Shabnam Pirestani et al. Anna C Lilly et al.
Levels of pancreatic ductal adenocarcinoma (PDAC) are increasing, with epidemiological studies nominating obesity, altered cholesterol metabolism, and elevated lipids as risk factors. In prior studies, we determined that elevated expression...
Yuejiao Zhong,Xuemei Zhou,Yuan Zhou et al. Yuejiao Zhong et al.
Liver metastasis is a major cause of mortality in gastric cancer (GC), yet the underlying molecular mechanisms remain poorly understood. Long non-coding RNAs (lncRNAs) have emerged as key regulators of gene expression and cancer progression...
Siwei Li,Yajie Gong,Hui Li et al. Siwei Li et al.
Hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR + /HER2 - ) breast cancer, the most common subtype, shows a low pathological complete response (pCR) rate and limited benefit from immunotherapy, highlighting ...
Shuai Tian,Shuchen Gu,Shuangwu Sun et al. Shuai Tian et al.
Transforming growth factor-β (TGF-β) is a multifunctional cytokine that regulates cell proliferation, differentiation, migration, and apoptosis. It is generally accepted that TGF-β induces cellular responses through Smad-dependent gene t...
Xuemei Lv,Li Han,Wei-Wei Tong et al. Xuemei Lv et al.
PKM serves as a rate-limiting enzyme in glycolysis, which produces two isoforms depending on the inclusion of either exon 9 (PKM1) or exon 10 (PKM2). The M2 pyruvate kinase (PKM2) isoform is commonly upregulated in various cancers, where it...
Weiwei Zong,Chunxiao Cheng,Yukun Zhang et al. Weiwei Zong et al.
Hepatocellular carcinoma (HCC), the most common subtype of primary liver cancer, is characterized by a poor prognosis, with most patients diagnosed at advanced stages that are unresectable and resistant to targeted therapies. This underscor...
Silvia Pietrobono,Veronica De Vita,Domenico Mangiameli et al. Silvia Pietrobono et al.
Transforming growth factor-β (TGFβ) receptor ALK5 inhibition has shown promise in pancreatic ductal adenocarcinoma (PDAC), but predictive biomarkers remain undefined. We identify angiogenin (ANG) as a negative prognostic yet positive pred...
Fan Wang,Meng Huang,Kaixuan Sheng et al. Fan Wang et al.
Metabolic reprogramming is a hallmark of tumorigenesis and progression in hepatocellular carcinoma (HCC) and has emerged as a promising therapeutic strategy. Forkhead box O3 (FOXO3), a critical nuclear transcription factor, is dysregulated ...