Ray Zhang,Longgui Chen,Xinwen Liang et al.
Ray Zhang et al.
The AAA+ ATPase VPS4 drives the ESCRT machinery in diverse intracellular membrane remodeling events, including endocytic receptor sorting, membrane repair, and autophagosome closure. Tumor cells often lose one VPS4 paralog (VPS4A or VPS4B),...
Stress granules promote DNA damage repair through the G3BP1/NAT10/ATF3 axis to facilitate nasopharyngeal carcinoma progression [0.03%]
Tian Yue,Haimeng Yin,Ling Yuan et al.
Tian Yue et al.
Aberrantly enhanced DNA damage repair contributes to therapy resistance and poor prognosis in nasopharyngeal carcinoma (NPC), but its regulatory mechanisms remain unclear. Stress granules (SGs) mediate tumor stress adaptation, yet their rol...
Qianlong Dai,Lei Lou,Xiaojie Zhu et al.
Qianlong Dai et al.
The Hippo pathway is an evolutionarily conserved signaling cascade whose dysregulation is implicated in a wide range of diseases. While many RNA-binding proteins (RBPs) regulate this pathway through canonical functions such as modulating mR...
Correction: The splicing factor WBP11 mediates MCM7 intron retention to promote the malignant progression of ovarian cancer [0.03%]
Yuan Wei,Zhongshao Chen,Yingwei Li et al.
Yuan Wei et al.
Published Erratum
Oncogene. 2026 Apr 23. DOI:10.1038/s41388-026-03810-z 2026
USP7-mediated deubiquitination of the KEAP1-NRF2-HMOX1 axis enhances radioresistance in non-small cell lung cancer by suppressing ferroptosis [0.03%]
Jianwei Tang,Lei Xu,Zetian Gong et al.
Jianwei Tang et al.
Radioresistance remains the primary cause of radiotherapy failure in non-small cell lung cancer (NSCLC). This study investigated the regulatory role of HMOX1-mediated ferroptosis in NSCLC radiosensitivity. Radioresistant cell models (H1650R...
Editorial Expression of Concern: Effects of ErbB-2 overexpression on mitogenic signalling and cell cycle progression in human breast luminal epithelial cells [0.03%]
John F Timms,Sarah L White,Michael J O&#x;Hare et al.
John F Timms et al.
PIWIL1 activates the R2TP-TELO2-mTORC1 axis independently of piRNA to promote TOP mRNA translation in gastric cancer [0.03%]
Tianqu Fan,Jiangsha Zhao,Ling Li et al.
Tianqu Fan et al.
PIWI proteins, a subfamily of the PAZ-PIWI domain (PPD) protein family, are traditionally regarded as germline factors that partner with PIWI-interacting RNAs (piRNAs) to silence transposons and regulate gene expression. However, growing ev...
Editorial Expression of Concern: YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity [0.03%]
表达关注函：YAP和MRTF-A是RhoA介导的基因转录共激活因子，对于胶质母细胞瘤致瘤性至关重要
Olivia M Yu,Jorge A Benitez,Steven W Plouffe et al.
Olivia M Yu et al.
SAMD4 represses VGLL4 mRNA to activate TEAD and promote cancer progression [0.03%]
SAMD4通过抑制VGLL4 mRNA激活TEAD并促进癌症进展
Junji Otani,Miki Nishio,Riko Tokita et al.
Junji Otani et al.
The transcriptional cofactors YAP1 and TAZ regulate target gene expression by binding to the transcription factor TEAD. Due to their roles in cancer initiation, progression, and drug resistance, YAP1 and TAZ are promising targets for cancer...
Targeting YRDC blocks codon-biased FABP7 translation and lipid droplet formation to overcome chemoresistance in glioblastoma [0.03%]
靶向YRDC通过偏倚密码子的FABP7翻译和脂滴形成来克服胶质母细胞瘤的化学抗性
Yuchao Zhang,Xuesong Yang,Xixi Li et al.
Yuchao Zhang et al.
Dysregulation of transfer RNA (tRNA) modification and reprogramming of codon-biased translation are commonly associated with cancer initiation and progression. However, their roles in chemoresistance and tumor recurrence remain poorly under...