Engineering of Saccharomyces cerevisiae to utilize xylan as a sole carbohydrate source by co-expression of an endoxylanase, xylosidase and a bacterial xylose isomerase [0.03%]
通过共表达内切木聚糖酶、木糖苷酶和细菌木糖异构酶工程改造酿酒酵母利用木聚糖作为单一碳源
Marlin John Mert,Daniël Coenrad la Grange,Shaunita Hellouise Rose et al.
Marlin John Mert et al.
Xylan represents a major component of lignocellulosic biomass, and its utilization by Saccharomyces cerevisiae is crucial for the cost effective production of ethanol from plant biomass. A recombinant xylan-degrading and xylose-assimilating...
Decreased fluidity of cell membranes causes a metal ion deficiency in recombinant Saccharomyces cerevisiae producing carotenoids [0.03%]
细胞膜流动性降低会导致类胡萝卜素生产重组酵母Saccharomyces cerevisiae中金属离子缺乏
Peitong Liu,Liang Sun,Yuxia Sun et al.
Peitong Liu et al.
The genome-wide transcriptional responses of S. cerevisiae to heterologous carotenoid biosynthesis were investigated using DNA microarray analysis. The results show that the genes involved in metal ion transport were specifically up-regulat...
Leonard Katz,Richard H Baltz
Leonard Katz
Microorganisms have provided abundant sources of natural products which have been developed as commercial products for human medicine, animal health, and plant crop protection. In the early years of natural product discovery from microorgan...
Improved pinocembrin production in Escherichia coli by engineering fatty acid synthesis [0.03%]
工程化脂肪酸合成以提高大肠杆菌中 pinocembrin 的产量
Weijia Cao,Weichao Ma,Bowen Zhang et al.
Weijia Cao et al.
The development of efficient microbial processes for pinocembrin production has attracted considerable attention. However, pinocembrin biosynthetic efficiency is greatly limited by the low availability of the malonyl-CoA cofactor in Escheri...
Streptomyces sanglieri which colonised and enhanced the growth of Elaeis guineensis Jacq. seedlings was antagonistic to Ganoderma boninense in in vitro studies [0.03%]
丛枝菌根促生放线菌桑吉利链霉菌的分离及其对刚果红根腐病原菌具有的抑制作用
A B Nur Azura,M Yusoff,G Y A Tan et al.
A B Nur Azura et al.
Actinomycete strain AUM 00500 was 99.5 % similar to Streptomyces sanglieri NBRC 100784(T) and was evaluated for antagonistic activity towards Ganoderma boninense, the causative fungus of basal stem rot of oil palm. The strain showed strong ...
Enhanced succinic acid productivity by expression of mgtCB gene in Escherichia coli mutant [0.03%]
大肠杆菌突变体中过表达mgtCB基因提高丁二酸产量
Jing Wang,Le Yang,Dan Wang et al.
Jing Wang et al.
In this study, a novel engineering Escherichia coli strain (CBMG111) with the expression of mgtCB gene was constructed for the enhanced fermentative production of succinic acid by utilizing the synergetic effect of mgtC gene to improve the ...
Efficient extracellular expression of Bacillus deramificans pullulanase in Brevibacillus choshinensis [0.03%]
解淀粉芽孢杆菌支链淀粉酶在短小芽孢杆菌中的高效分泌表达
Chun Zou,Xuguo Duan,Jing Wu
Chun Zou
In this study, the pullulanase gene from Bacillus deramificans was efficiently expressed in Brevibacillus choshinensis. The optimal medium for protein expression was determined through a combination of single-factor experiments and response...
Discovery and development of surotomycin for the treatment of Clostridium difficile [0.03%]
杀霉素治疗艰难梭菌感染的研发及其进展
Victoria Knight-Connoni,Carmela Mascio,Laurent Chesnel et al.
Victoria Knight-Connoni et al.
The primary challenge for treating Clostridium difficile infections (CDI) is maintenance of clinical response after the end of treatment (sustained clinical response). Disease recurrence following a positive clinical response occurs in appr...
Biobutanol production from C5/C6 carbohydrates integrated with pervaporation: experimental results and conceptual plant design [0.03%]
基于C5/C6碳水化合物的生物丁醇生产与渗透汽化的集成：实验结果及概念性工艺设计
Wouter Van Hecke,Pieter Vandezande,Marjorie Dubreuil et al.
Wouter Van Hecke et al.
In this study, a simulated lignocellulosic hydrolyzate was used in a continuous two-stage fermentor setup for production of acetone, butanol and ethanol. An organophilic pervaporation unit was coupled to the second fermentor. The dilution r...
Improvement of lactic acid production in Saccharomyces cerevisiae by a deletion of ssb1 [0.03%]
通过删除SSB1基因提高酿酒酵母乳酸生成量
Jinsuk J Lee,Nathan Crook,Jie Sun et al.
Jinsuk J Lee et al.
Polylactic acid (PLA) is an important renewable polymer, but current processes for producing its precursor, lactic acid, suffer from process inefficiencies related to the use of bacterial hosts. Therefore, improving the capacity of Saccharo...