Exploring the compatibility of phosphopantetheinyl transferases with acyl carrier proteins spanning type II polyketide synthase sequence space [0.03%]
泛酮合酶序列空间中酰基载体蛋白与磷酸潘théine转移酶的兼容性研究
Areta L N Bifendeh,Kenneth K Hsu,Christina M McBride et al.
Areta L N Bifendeh et al.
Phosphopantetheinyl transferases (PPTases) play an essential role in primary and secondary metabolism. These enzymes facilitate the post-translational activation of acyl carrier proteins (ACPs) central to the biosynthesis of fatty acids and...
Biochemical production of bio-based terephthalic acid from lignocellulosic biomass for CO2 emission reduction [0.03%]
以木质纤维素类生物质为原料生化制备生物基对苯二甲酸以减少二氧化碳排放
Seiji Nakagame,Takuma Kawao,Daiki Narita et al.
Seiji Nakagame et al.
Terephthalic acid, a key precursor for polyester production, is traditionally derived from fossil resources, contributing to global warming. Although numerous studies have explored the production of terephthalic acid from biomass polysaccha...
A Multi-Clone Kinetic Model for Characterising CHO Cell Line Variability [0.03%]
用于表征中国仓鼠卵巢细胞系多样性的多克隆动力学模型
Devi Sietaram,Pavlos Kotidis,Gary Finka et al.
Devi Sietaram et al.
This paper presents the Multi Clone Kinetic Model (MCKM), a novel generalised kinetic mechanistic model for fed-batch cultivations of diverse Chinese Hamster Ovary (CHO) cell lines, producing different recombinant monoclonal antibodies (mAb...
Characterization of S-glycosylated glycocins containing three disulfides [0.03%]
含三个二硫键的S-糖基化糖肽的特征分析
Rachel M Martini,Chandrashekhar Padhi,Wilfred A van der Donk
Rachel M Martini
Glycocins are a growing family of ribosomally synthesized and posttranslationally modified peptides (RiPPs) that are O- and/or S-glycosylated. Using a sequence similarity network of putative glycosyltransferases, the thg biosynthetic gene c...
Anti-Parkinsonian 4-hydroxy-2-pyridones from an endolichenic fungus, Tolypocladium sp. (strain CNC14) [0.03%]
来自内生真菌Tolypocladium属（菌株CNC14）的抗帕金森病4-羟基-2-吡啶酮类化合物
Jin Won Choi,Chaesun Kwon,Jin Woo Lee et al.
Jin Won Choi et al.
4-Hydroxy-2-pyridone alkaloids have attracted considerable attention because of their intriguing structures and diverse bioactivities. In our previous study, 4-hydroxy-2-pyridone alkaloids were shown to exhibit potent activity against neuro...
Screening of cellulose-degrading bacteria and its degradation and growth-promoting applications [0.03%]
纤维素降解菌的筛选及其在纤维素降解和促生长方面的应用
Mengke Chen,Xuebin Li,Er Meng et al.
Mengke Chen et al.
More than one billion tons of chaff waste are generated globally every year, but traditional recycling methods face the dual challenges of inefficiency and environmental risks, to solve this problem, this study innovatively achieves the dua...
Thermophilic site-specific recombination system for rapid insertion of heterologous DNA into the Clostridium thermocellum chromosome [0.03%]
耐热特异位点重组系统可快速将异源DNA插入Clostridium thermocellum染色体中
Nandhini Ashok,Yasemin Kaygusuz,Heidi S Schindel et al.
Nandhini Ashok et al.
Clostridium thermocellum is an anaerobic thermophile capable of producing ethanol and other commodity chemicals from lignocellulosic biomass. The insertion of heterologous DNA into the C. thermocellum chromosome is currently achieved via a ...
Towards Sustainable Agarwood Production: Integrating Microbial Interactions, Anatomical Changes, and Metabolite Biosynthesis [0.03%]
迈向沉香可持续生产的微生物、解剖和次生代谢整合研究
Yashirdisai Sampasivam,Khalisah Khairina Razman,Nor Syakila Mohd Mazlan et al.
Yashirdisai Sampasivam et al.
Agarwood is a highly valuable non-timber forest product mainly derived from the Aquilaria genus, widely traded in the perfumery, religious items, and traditional medicine industries. Naturally, agarwood forms within the xylem as part of the...
Wenhe Zhang,Richiro Ushimaru
Wenhe Zhang
Cyanobacteria are prolific producers of structurally diverse and biologically potent natural products, a subset of which feature guanidino moieties. Introduction and modification of the guanidine group confer tuned basicity and enable exten...
Discovering methylated DNA motifs in bacterial nanopore sequencing data with MIJAMP [0.03%]
使用MIJAMP在细菌纳米孔测序数据中发现甲基化DNAmotif
Alyssa K Tidwell,Evelyn Faust,Carrie A Eckert et al.
Alyssa K Tidwell et al.
Bacterial DNA methylation is involved in diverse cellular functions ranging from modulation of gene expression, DNA repair, and restriction-modification systems for defense against viruses and other foreign DNA. Restriction systems hinder e...