Maternal high-fat high-energy diet impairs surfactant maturation in the non-human primate fetal lung [0.03%]
高脂高能量饮食通过影响非人灵长类动物胎儿肺表面活性物质的成熟而导致子代肺功能不全
Mitchell C Lock,Hillary F Huber,Cun Li et al.
Mitchell C Lock et al.
Introduction: Due to the global obesity crisis, increasing numbers of women enter pregnancy with overweight or obesity. Their offspring are at greater risk of respiratory complications at birth due to metabolic changes th...
GLP-1 agonists and changes in body mass and composition in adults with overweight or obesity with or without type 2 diabetes mellitus: a systematic review and meta-analysis [0.03%]
胰高糖素样肽-1受体激动剂对超重或肥胖伴或不伴有2型糖尿病成人患者身体质量和组成的改变：系统综述和荟萃分析
Nadia Sawicka-Gutaj,Dawid Gruszczyński,Kacper Nijakowski et al.
Nadia Sawicka-Gutaj et al.
Background: The systematic review aimed to assess the effects of GLP-1 receptor agonists (GLP-1 RA) and dual GLP-1/GIP agonists on weight loss and body composition in individuals with overweight or obesity, with or withou...
Bariatric surgery and subsequent weight loss lead to a reversal of peripheral blood monocytosis in obesity [0.03%]
代谢手术与后续的体重减轻可逆转肥胖患者的外周血单核细胞增多现象
Marco Krasselt,Kathleen Friedrich,Laurin Braune et al.
Marco Krasselt et al.
Objective: To examine changes in monocyte subpopulations and surface markers in people with obesity before and after bariatric surgery, and their relation to weight loss, inflammation markers, and comorbidities. ...
Circulating lipid subfractions and the risk of longitudinal adiposity progression: findings from the China Kadoorie Biobank [0.03%]
循环脂蛋白亚组分与肥胖进展的关系：中国-卡迪奥瑞生物库研究发现
Menghan Wang,Haozhi Niu,Huaidong Du et al.
Menghan Wang et al.
Background: This study examined the associations between circulating lipid subfractions and long-term adiposity progression, and identified biomarkers reflecting baseline obesity status and future adiposity change. ...
Detecting drug-related problems following metabolic and bariatric surgery using pharmacovigilance databases [0.03%]
采用药物警戒数据库检测代谢和减肥手术后的药物相关问题
Cedric Lau,Robert M Smeenk,Florence P A M van Hunsel et al.
Cedric Lau et al.
Background: Clinical data on changes in drug pharmacokinetics and pharmacodynamics following metabolic and bariatric surgery (MBS) remain limited and largely drug-specific. This study summarized cases of changed drug acti...
Metabolically healthy obesity is independently associated with 20-year incidence of cardiovascular disease: findings from the ATTICA cohort study (2002-2022) [0.03%]
代谢健康型肥胖症与20年心血管疾病发病率独立相关：来自ATTICA队列研究（2002-2022）的发现
Theodosios D Filippatos,Panagiotis Katrapas,Thomas Tsiampalis et al.
Theodosios D Filippatos et al.
Background: Individuals with excess body weight do not share the same risk for cardiovascular disease (CVD). The phenotype of metabolically healthy obesity (MHO) has drawn the attention of the scientific community due to ...
Childhood adversity and gestational diabetes: examining the mediating effect of BMI and depression through interventional mediation analysis [0.03%]
童年逆境与妊娠期糖尿病：通过干预性中介分析考察BMI和抑郁的中介作用
Megan Davies,Bianca De Stavola,Karoline Kragelund Nielsen et al.
Megan Davies et al.
Background: Childhood adversity has been shown to increase the risk of gestational diabetes mellitus (GDM), though the mechanisms through which the risk is increased have yet to be examined. ...
Association of cord blood mitochondrial DNA heteroplasmy and copy number with childhood overweight or obesity [0.03%]
新生儿脐带血线粒体DNA杂合度和拷贝数与儿童期超重或肥胖的关系研究
Xueqi Qu,Guoying Wang,Xiumei Hong et al.
Xueqi Qu et al.
Background: Mitochondria, the cell's powerhouse, play a central role in energy homeostasis and may influence obesity risk. Variations in mitochondrial DNA (mtDNA) have been hypothesized to influence early-life metabolic p...
The association of prenatal adiposity characteristics with early childhood overweight and obesity: findings from a large and diverse mother-child cohort [0.03%]
孕期肥胖与幼儿期超重和肥胖的关系：来自母亲-儿童队列的大样本、多族群研究结果
Hua Min,Michael S Bloom,Grace N Lawrence et al.
Hua Min et al.
Background: Maternal prepregnancy body mass index (ppBMI) and gestational weight gain (GWG) are risk factors for overweight and obesity (OWO) in childhood. However, a better understanding of the magnitude, timing, and med...
Racial and ethnic variations of metabolic indicators associated with childhood obesity: a comparative cross-sectional study [0.03%]
与儿童肥胖症相关的代谢指标的种族和族裔差异：一项比较横断面研究
Jing Wu,Zhenran Xu,Li Xi et al.
Jing Wu et al.
Background: Susceptibility to adult metabolic diseases varies significantly across ethnicities. Asian adults exhibit elevated risks associated with obesity at lower body mass index (BMI) levels; whether similar patterns o...