Effect of GLP-1 receptor agonists at doses for obesity management on muscle health: systematic review and meta-analysis of randomized controlled trials (RCTs) [0.03%]
作用于肥胖人群剂量的GLP-1受体激动剂对肌肉健康的影响:随机对照试验的系统评价和meta分析
Ligia Patricia Laverde,Oscar Mauricio Muñoz-Velandia,Diana Alfonso et al.
Ligia Patricia Laverde et al.
Introduction: The impact of GLP-1 receptor agonists (GLP1-RA) treatment on lean mass and body composition in patients with obesity is not fully understood. ...
Toward an intergenerational model of metabolic and bariatric surgery: reframing the household as the unit of care [0.03%]
面向代谢和减肥手术的代际模型:将家庭作为护理单元重新构建
Alaina P Vidmar,Kamran Samakar,Matthew J Martin et al.
Alaina P Vidmar et al.
Obesity is a chronic, relapsing disease that increasingly spans generations within households, yet contemporary metabolic and bariatric surgery (MBS) models remain oriented toward individuals or single-generation patients. A growing body of...
Cardiovascular disease and metabolic dysfunction-associated steatotic liver disease incidence in metabolically healthy and unhealthy normal weight obesity [0.03%]
代谢健康与不健康正常体重肥胖者心血管疾病和与代谢功能障碍相关脂肪变性肝病的发病率
Parker R Johnson,Bryant H Keirns,Gracie E Meade et al.
Parker R Johnson et al.
Background: Normal weight obesity (NWO) is characterized by a normal body mass index (BMI) and elevated body fat. Heterogeneous risk has been observed in people with obesity (BMI > 30) when considering metabolic risk fact...
Alcohol use disorders and related morbidity and mortality after sleeve gastrectomy and Roux-en-Y gastric bypass: a nation-wide registry study (the BAR-REGISTER) [0.03%]
袖状胃切除术和Roux-en-Y胃旁路手术成年后酒精使用障碍及相关发病率和死亡率的全国范围登记处研究(BAR-REGISTER)
Magnus Strømmen,Inger Johanne Bakken,Jorunn Sandvik et al.
Magnus Strømmen et al.
Background: Bariatric surgery provides notable weight loss and metabolic benefits but may also increase the risk of alcohol use disorder (AUD). We investigated whether Roux-en-Y gastric bypass (RYGB) confers higher rates ...
Ethanol pharmacokinetics before and after sleeve gastrectomy and Roux-en-Y gastric bypass: a 3 year prospective study (the BAR-TRIAL) [0.03%]
袖状胃切除术和胃旁路手术前后乙醇药代动力学的三年前瞻性研究(BAR-TRIAL)
Magnus Strømmen,Ola Dale,Christian Klöckner et al.
Magnus Strømmen et al.
Objectives: To compare ethanol pharmacokinetics before and after Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) over a three-year period. Met...
Novel perspectives on PPARγ regulation: from SPPARMs to the emerging role of lncRNAs in metabolic disorders [0.03%]
核受体PPARγ调控新视角:从选择性PPARγ调节剂到长链非编码RNA在代谢性疾病中的作用机制初探
Hao Qin,YuanYuan Wang,Yukai Yang et al.
Hao Qin et al.
Metabolic disorders-particularly obesity and type 2 diabetes mellitus (T2DM)-have reached pandemic proportions and represent one of the most pressing global health challenges of the 21st century. Peroxisome proliferator-activated receptor g...
Metabolism-disrupting compounds and metabolic health during the menopausal transition: a narrative review [0.03%]
围绝经期代谢干扰物与代谢健康:综述
Heather M Guetterman,Jodi A Flaws,Rita S Strakovsky
Heather M Guetterman
Substantial evidence has linked endocrine-disrupting chemicals and other compounds to increased risk of elevated adiposity and adverse metabolic outcomes. Individuals may be particularly susceptible to these metabolism-disrupting chemicals ...
Association between immune-inflammatory biomarkers (NLR, PLR, SII, SIRI) and obesity in adults: a systematic review and meta-analysis [0.03%]
成人免疫炎症生物标志物(NLR、PLR、SII、siri)与肥胖相关性的系统评价和meta分析
Yunyi Yang,Jingxiao Wang,Jiayuan Cai et al.
Yunyi Yang et al.
Background: Obesity is regarded as a chronic, low-grade systemic inflammatory condition. However, whether immune-inflammatory indices derived from routine peripheral blood tests-including the neutrophil-to-lymphocyte rati...
Genetic and environmental influences on educational disparities in adult weight change: an individual-based pooled analysis of 11 twin cohorts [0.03%]
遗传和环境因素对成人教育差距导致的体重变化的影响:来自11个双胞胎队列的个体层面荟萃分析
Alvaro Obeso,Gabin Drouard,Aline Jelenkovic et al.
Alvaro Obeso et al.
Introduction: Educational attainment (EA) is negatively associated with body mass index (BMI), but less is known about the association between EA and adult BMI change. We analysed the role of genetic and environmental fac...
Capturing infant and child growth dynamics with P-splines mixed effects models [0.03%]
基于P-样条混合效应模型捕捉婴幼儿生长轨迹动态变化
María Alejandra Hernandez,Zheyuan Li,Tim J Cole et al.
María Alejandra Hernandez et al.
Background: Investigating early life growth dynamics is important for understanding the developmental origins of obesity. Basis splines (B-splines) provide excellent flexibility for modelling complex growth patterns, but ...