Plasma metabolites may inhibit childhood obesity by regulating ferroptosis through SMPD1 and SIRT3 [0.03%]
血浆代谢产物通过SMPD1和SIRT3调节铁死亡或可预防儿童肥胖
Ji-Gan Wang,Xiu-Hua Pan,Yan Li
Ji-Gan Wang
Objective: To investigate the causal relationship between plasma metabolites and ferroptosis-related genes in childhood obesity and to explore the potential mediating role of ferroptosis-related genes in the association b...
The Physiology Of the WEight Reduced State (POWERS) study: assessing energy balance [0.03%]
体重减少状态(POWERS)研究：评估能量平衡
Michael Rosenbaum,Kelly C Allison,Maren R Laughlin et al.
Michael Rosenbaum et al.
Background/objectives: We provide the rationale for and description of energy balance measures (i.e., energy intake and energy expenditure) in The Physiology Of the WEight Reduced State (POWERS) study which aims to unders...
Long-term trends in central obesity in England: an age-period-cohort approach [0.03%]
英国中央型肥胖的长期趋势——基于年龄、时期和世代的分析
Laura A Gray,Magdalena Opazo Breton
Laura A Gray
Background: Central obesity measures, such as waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) have previously outperformed body mass index (BMI) in predicting health risks. BMI has bee...
Bridging the nutrition guidance gap for GLP-1 receptor agonist therapy assisted weight loss: lessons from bariatric surgery [0.03%]
GLP-1受体激动剂辅助减肥的营养指导缺口及代谢手术的借鉴意义
Marie Spreckley,Cara F Ruggiero,Adrian Brown
Marie Spreckley
Maternal pre-pregnancy body mass index and the risk of neurodevelopmental disorders in offspring [0.03%]
孕前体重指数与子代神经发育障碍的发病风险关系研究
Hye Won Park,Tae-Eun Kim,Sanghyun Park et al.
Hye Won Park et al.
Background: The global increase in maternal obesity has raised concerns regarding its potential impact on offspring neurodevelopment. This study investigated the association between maternal pre-pregnancy body mass index ...
Weight loss normalizes plasma and adipose tissue vitamin D metabolism, and gene expression involved in the vitamin D metabolism in male mice with obesity [0.03%]
体重减轻可使肥胖小鼠的维生素D代谢和与维生素D代谢相关的基因表达正常化
Lauriane Bonnet,Amine Hachemi,Esma Karkeni et al.
Lauriane Bonnet et al.
Background: Obesity has consistently been linked to lower circulating total and free 25-hydroxyvitamin D (25(OH)D), and weight loss has been shown to enhance 25(OH)D levels in individuals with obesity. We examined whether...
Correction: Quality of life improvements associated with weight loss using a novel shape-shifting hydrogel capsule: RESET study results [0.03%]
关于使用一种新型形状可变的水凝胶胶囊减肥后的生活质量改善的更正：RESET研究结果
Robert F Kushner,Jamy D Ard,Thomas A Wadden et al.
Robert F Kushner et al.
Published Erratum
International journal of obesity (2005). 2025 Nov 13. DOI:10.1038/s41366-025-01962-8 2025
Introduction to the special issue describing the Physiology Of the WEight Reduced State (POWERS) Study [0.03%]
“WEight Reduced State（POWERS）研究专刊前言”
Steven H Belle,Susan B Roberts,Dympna Gallagher et al.
Steven H Belle et al.
The role of SIRT4 in obesity: from molecular mechanisms to clinical implications [0.03%]
SIRT4在肥胖中的作用：从分子机制到临床意义
Yuchen Shi,Mengpan Cao,Kexin Wang et al.
Yuchen Shi et al.
Obesity has emerged as a pervasive global public health issue, and the etiology of obesity is now understood to be increasingly intricate and multifactorial, encompassing genetic predispositions, sedentary lifestyles coupled with excessive ...