Ludger Johannes,Cesar Augusto Valades-Cruz
Ludger Johannes
Zhe Wang
Zhe Wang
Jie Wang
Jie Wang
Melina Casadio
Melina Casadio
Christine Weber
Christine Weber
Targeting liquid-liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity [0.03%]
针对SARS-CoV-2核衣壳蛋白液-液相分离以促进固有抗病毒免疫并提高MAVS活性
Shuai Wang,Tong Dai,Ziran Qin et al.
Shuai Wang et al.
Patients with Coronavirus disease 2019 exhibit low expression of interferon-stimulated genes, contributing to a limited antiviral response. Uncovering the underlying mechanism of innate immune suppression and rescuing the innate antiviral r...
Alessia Zotta,Alexander Hooftman,Luke A J O&#x;Neill
Alessia Zotta
E-type prostanoid receptor 4 drives resolution of intestinal inflammation by blocking epithelial necroptosis [0.03%]
E型前列腺素受体4通过抑制上皮细胞坏死性凋亡驱动肠道炎症消退
Jay V Patankar,Tanja M Müller,Srinivas Kantham et al.
Jay V Patankar et al.
Inflammatory bowel diseases present with elevated levels of intestinal epithelial cell (IEC) death, which compromises the gut barrier, activating immune cells and triggering more IEC death. The endogenous signals that prevent IEC death and ...
Nicole C Kaneider,Arthur Kaser
Nicole C Kaneider
Niche stiffening compromises hair follicle stem cell potential during ageing by reducing bivalent promoter accessibility [0.03%]
小生境硬化通过减少双价启动子的可及性，在衰老过程中损害毛囊干细胞潜能
Janis Koester,Yekaterina A Miroshnikova,Sushmita Ghatak et al.
Janis Koester et al.
Tissue turnover requires activation and lineage commitment of tissue-resident stem cells (SCs). These processes are impacted by ageing, but the mechanisms remain unclear. Here, we addressed the mechanisms of ageing in murine hair follicle S...