CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1 [0.03%]
利用表观遗传修饰因子NCAPD2和MTHFD1在人胰腺癌异种移植瘤中进行CRISPR筛选鉴定出KLF5增殖弱点
Masahiro Maeda,Kenna Sherman,Weiqiang Zhou et al.
Masahiro Maeda et al.
Exploiting synthetic lethality in epithelial ovarian cancer: multi-dimensional approaches beyond DNA damage repair [0.03%]
上皮性卵巢癌合成致死性的多维度研究：DNA修复之外的诸多途径
Mandana Bigdeli,Elizabeth Tremblay,Diane Provencher et al.
Mandana Bigdeli et al.
Synthetic lethality (SL) is a therapeutic approach that selectively target cancer cells via the disruption of two interdependent molecular targets, which together become essential in the cancer context to ensure cancer cell survival. Among ...
Spatial single-cell multi-omics characterization of the tumor microenvironment heterogeneity by HER-2 expression status in gastric cancer : Author list [0.03%]
基于HER-2表达状态的空间单细胞多组学表征胃癌肿瘤微环境异质性：作者名单
Haoxin Peng,Yang Chen,Qian Yao et al.
Haoxin Peng et al.
HnRPD/AUF1 facilitates human ovarian cancer progression through activating FLI1 and maintaining cisplatin resistance [0.03%]
hnRNP D/AUF1通过激活FLI1并维持顺铂耐药性来促进人类卵巢癌进展
Chao Tang,Chongying Zhu,Zihao An et al.
Chao Tang et al.
Ovarian cancer (OC) is the predominant gynecological cancer and is associated with severe morbidity and high mortality worldwide. Therefore, clarifying the molecular mechanisms underlying OC progression and exploring novel therapeutic targe...
miRNA-driven cancer cell plasticity, tolerance and therapy resistance: lessons from melanoma [0.03%]
微小核糖核酸驱动的癌细胞可塑性、耐受性和治疗抵抗性：来自黑色素瘤的经验与教训
Arianna Ortolano,Rachele Frigerio,Gennaro Ciliberto et al.
Arianna Ortolano et al.
Tumour-infiltrating microplastics disrupt the JAK-STAT-microbiota axis to promote immunotherapy resistance in colorectal cancer [0.03%]
肿瘤组织浸润的微塑料通过干扰JAK-STAT-肠道微生物轴促进结直肠癌免疫治疗耐药性
Zhaohui Jiang,Yongting Liu,Peng Zhang et al.
Zhaohui Jiang et al.
STING-Activating nanoplatforms for image-guided sonodynamic cancer therapy [0.03%]
用于引导声动力癌症治疗的STING激活纳米平台
Lingpu Zhang,Delong Huang,Jia Li et al.
Lingpu Zhang et al.
Tumor precision treatment still faces the challenge of being unable to achieve real-time monitoring. The rapid advancements in nanomedicine within the biomedical sector have highlighted the potential of integrated nano-platforms for tumor d...
Correction: The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment [0.03%]
订正：通过调节肿瘤微环境，染色体11q13.3扩增相关淋巴结转移由miR-548k驱动
Weimin Zhang,Ruoxi Hong,Lin Li et al.
Weimin Zhang et al.
Published Erratum
Molecular cancer. 2026 Feb 9;25(1):27. DOI:10.1186/s12943-026-02586-w 2026
Correction: Histone demethylase KDM4D promotes gastrointestinal stromal tumor progression through HIF1β/VEGFA signalling [0.03%]
纠正：组蛋白去甲基酶KDM4D通过HIF1β / VEGFA信号促进胃肠道间质瘤的进展
Fuqing Hu,Haijie Li,Lu Liu et al.
Fuqing Hu et al.
Published Erratum
Molecular cancer. 2026 Feb 9;25(1):26. DOI:10.1186/s12943-026-02579-9 2026
Therapeutic reprogramming of tumour-associated macrophages in pancreatic cancer using a cytotoxic CCR2-targeted nanotheranostic [0.03%]
用于胰腺癌治疗性重编程肿瘤相关巨噬细胞的细胞毒性CCR2靶向纳米诊疗剂
Vikas Kumar Somani,Xiaohui Zhang,Timothy Hung-Po Chen et al.
Vikas Kumar Somani et al.