Transcriptional networks weaving natural killer anti-tumor immune response [0.03%]
转录调控网络编织自然杀伤细胞的抗肿瘤免疫应答
Anna Rita Redavid,Martina Bigliardi,Alessia Ciarrocchi et al.
Anna Rita Redavid et al.
Targeting circGDI2 disrupt HNRNPC-mediated mPORCN stabilization and enhance LGK-974 anti-tumor therapy in hepatocellular carcinoma [0.03%]
circGDI2靶向抑制HNRNPC介导的mPORCN稳定并增强LGK-974在肝癌中的抗肿瘤作用
Yang Huang,Liangliang Xu,Linfeng Yang et al.
Yang Huang et al.
CircNSD2 promotes metastasis and immune escape by increasing the USP10/SRSF6-mediated alternative splicing of TPM1 in TNBC [0.03%]
圆环RNA CircNSD2通过增加USP10/SRSF6介导的TPM1在TNBC中促进转移和免疫逃逸的替代剪接
Yuhan Sun,Yaming Li,Tong Niu et al.
Yuhan Sun et al.
Retraction Note: Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer [0.03%]
撤回 notice: 肿瘤进展期间AMPK-β1的低表达增强了晚期卵巢癌的致癌潜能
Cuilan Li,Vincent Ws Liu,Pui Man Chiu et al.
Cuilan Li et al.
Low-dose radiotherapy remodels the tumor immune microenvironment via the cGAS-STING pathway: mechanisms, challenges, and combination therapy strategies [0.03%]
低剂量放射治疗通过cGAS-STING途径重塑肿瘤免疫微环境：机制、挑战及联合治疗策略
Yongze He,Xianhu Zeng,Qianyi Liu et al.
Yongze He et al.
Inhibition of PRMT5 triggers synthetic lethality in ARID1A-deficient endometrial cancer by promoting aberrant R-loop accumulation [0.03%]
PRMT5抑制造成合成致死性并通过促进异常R环累积引发ARID1A基因缺失型子宫内膜癌
Wan Shu,Kejun Dong,Xiaoyu Shen et al.
Wan Shu et al.
Molecular subtypes in pancreatic cancer: from academic promise to clinical reality [0.03%]
胰腺癌的分子亚型：从学术前景到临床现实
Daniela Mercedes D&#x;Empaire Altimari,Michele Bevere,Elisa Espinet et al.
Daniela Mercedes D&#x;Empaire Altimari et al.
Pancreatic ductal adenocarcinoma (PDAC) continues to rank among the most lethal malignancies, with five-year survival rates stubbornly below 12%. Over the past decade and a half, transcriptomic analyses have consistently identified molecula...
Machine learning model on multi-omics data enables risk stratification and identifies molecular heterogeneity and therapeutic targets in glioblastoma [0.03%]
基于多组学数据的机器学习模型可对胶质母细胞瘤进行风险分层、识别分子异质性和发现治疗靶点
Zhenyu Zhang,Zilong Wang,Ran Li et al.
Zhenyu Zhang et al.
Calibrating the RT-cGAS-STING axis to drive cold-to-hot tumor transformation: mechanistic foundations and translational strategies for combination with immunotherapy [0.03%]
校准RT-cGAS-STING轴以驱动冷肿瘤向热肿瘤转化的机制基础及与免疫治疗联合应用的转化策略
Yi-Fan Kang,Jin-Ming Chen,Bai-Cheng Xu et al.
Yi-Fan Kang et al.
Targeting HSP90 in cancer: advances in the development of inhibitors, mechanisms of action, and therapeutic applications [0.03%]
靶向HSP90治疗癌症：抑制剂开发、作用机制及应用研究进展
Xueyi Wang,Ruiqing Ni,Xiaohui Wang et al.
Xueyi Wang et al.