Tumor antigens and immune subtypes guided mRNA vaccine development for kidney renal clear cell carcinoma [0.03%]
肿瘤抗原和免疫亚型指导肾透明细胞癌的mRNA疫苗开发
Hang Xu,Xiaonan Zheng,Shiyu Zhang et al.
Hang Xu et al.
Current treatment strategy for kidney renal clear cell carcinoma (KIRC) is limited. Tumor-associated antigens, especially neoantigen-based personalized mRNA vaccines represent new strategies and manifest clinical benefits in solid tumors, b...
A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression [0.03%]
由circAXIN1编码的新蛋白AXIN1-295aa激活Wnt/β-catenin信号通路以促进胃癌进展
Yin Peng,Yidan Xu,Xiaojing Zhang et al.
Yin Peng et al.
Background: Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical role in cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a microRNA sponge or a scaffold to interact with p...
Correction to: ciRS-7 is a prognostic biomarker and potential gene therapy target for renal cell carcinoma [0.03%]
Corrigendum: ciRS-7是肾细胞癌的预后生物标志物和潜在基因治疗靶点
Weipu Mao,Keyi Wang,Bin Xu et al.
Weipu Mao et al.
Published Erratum
Molecular cancer. 2021 Dec 1;20(1):155. DOI:10.1186/s12943-021-01459-8 2021
LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathway [0.03%]
长链非编码RNA PKMYT1AR通过激活Wnt信号通路促进非小细胞肺癌癌症干细胞的维持
Yaomei He,Xiulin Jiang,Lincan Duan et al.
Yaomei He et al.
Background: Non-small cell lung cancer (NSCLC) is the most common type of human lung cancers, which has diverse pathological features. Although many signaling pathways and therapeutic targets have been defined to play imp...
EasyCatch, a convenient, sensitive and specific CRISPR detection system for cancer gene mutations [0.03%]
EasyCatch，一种方便、敏感且特异的癌症基因突变CRISPR检测系统
Yin Liu,Yanling Chen,Lu Dang et al.
Yin Liu et al.
Cancer associated-fibroblast-derived exosomes in cancer progression [0.03%]
与癌症相关的成纤维细胞源性外泌体在癌症进展中的作用
Chao Li,Adilson Fonseca Teixeira,Hong-Jian Zhu et al.
Chao Li et al.
To identify novel cancer therapies, the tumor microenvironment (TME) has received a lot of attention in recent years in particular with the advent of clinical successes achieved by targeting immune checkpoint inhibitors (ICIs). The TME cons...
CircEAF2 counteracts Epstein-Barr virus-positive diffuse large B-cell lymphoma progression via miR-BART19-3p/APC/β-catenin axis [0.03%]
circEAF2通过miR-BART19-3p/APC/β-连环蛋白轴抑制EB病毒阳性弥漫性大B细胞淋巴瘤进展
Chen-Xing Zhao,Zi-Xun Yan,Jing-Jing Wen et al.
Chen-Xing Zhao et al.
Background: Epstein-Barr virus (EBV) represents an important pathogenic factor of lymphoma and is significantly associated with poor clinical outcome of diffuse large B-cell lymphoma (DLBCL). Circular RNAs (circRNAs) play...
Correction to: Antagonizing miR-455-3p inhibits chemoresistance and aggressiveness in esophageal squamous cell carcinoma [0.03%]
对抗miR-455-3p抑制食管鳞状细胞癌的化疗抗性和侵袭性的修正
Aibin Liu,Jinrong Zhu,Geyan Wu et al.
Aibin Liu et al.
Published Erratum
Molecular cancer. 2021 Dec 1;20(1):152. DOI:10.1186/s12943-021-01425-4 2021
Liquid biopsy identifies actionable dynamic predictors of resistance to Trastuzumab Emtansine (T-DM1) in advanced HER2-positive breast cancer [0.03%]
液体活检确定了曲妥珠单抗艾姆坦嗪(T-DM1)治疗晚期HER2阳性乳腺癌的可操作动态预测性耐药因素
Matteo Allegretti,Alessandra Fabi,Elena Giordani et al.
Matteo Allegretti et al.
Remodeling of the tumor microenvironment via disrupting Blimp1+ effector Treg activity augments response to anti-PD-1 blockade [0.03%]
通过破坏Blimp1+效应Treg活性改良肿瘤微环境可增强对PD-1阻断的反应
Michael L Dixon,Lin Luo,Sadashib Ghosh et al.
Michael L Dixon et al.
Background: Accumulation of Foxp3+ regulatory T (Treg) cells in the tumor often represents an important mechanism for cancer immune evasion and a critical barrier to anti-tumor immunity and immunotherapy. Many tumor-infil...