Trifloxystrobin-Induced Neurotoxicity in Wistar Rats: Biomarkers of Oxidative Stress, Cholinergic Dysfunction, and DNA Damage [0.03%]
trifloxystrobin致Wistar大鼠神经毒性:氧化应激、胆碱能功能损伤及DNA损伤的生物标志物研究
Hanen Chaabani,Asma Mnassri,Siwar Rich et al.
Hanen Chaabani et al.
Protective Effects of Ozone against Quinolinic Acid-Induced Redox Imbalance in Murine BV-2 Microglial Cells [0.03%]
臭氧通过Nrf2抗氧化信号通路对抗喹啉酸诱导的小胶质细胞BV-2氧化应激损伤的作用研究
Pedro Henrique Zatti,Nicole Peyrot da Silva,Marina Rigotti et al.
Pedro Henrique Zatti et al.
Ozone gas (O₃) has emerged as a promising therapeutic agent for various pathological conditions, including neurodegenerative diseases (NDs). These illnesses are associated with the accumulation of neurotoxic metabolites by microglia, inclu...
MicroRNA-132 Alleviates Ischemia-Reperfusion-Induced Neuronal Apoptosis by Targeting Mecp2 in Stroke Models [0.03%]
microRNA-132通过靶向Mecp2缓解卒中模型缺血再灌注诱导的神经元凋亡
Xiang Wang,Rui Ma,Zilu Liu et al.
Xiang Wang et al.
Cerebral ischemia-reperfusion injury (CI/RI) remains a significant challenge in ischemic stroke treatment, often leading to exacerbated neuronal apoptosis and poor neurological recovery despite successful recanalization. MicroRNAs (miRNAs) ...
Associations between air pollution and markers of neuroinflammation, synaptic dysfunction and core Alzheimer's disease pathology vary by APOE genotype [0.03%]
基于APOE基因型,空气污染与神经炎症标志物、突触功能障碍及阿尔茨海默病核心病理特征之间的关联不同
Kana Kimura,Ira Driscoll,Noah Cook et al.
Kana Kimura et al.
To determine whether long-term residential air pollution [AP; ozone (O₃) and fine particulate matter (PM₂.₅)] is associated with (1) incident mild cognitive impairment (MCI) or Alzheimer’s disease (AD), (2) biomarkers of core and AD-rel...
Lipopolysaccharide-induced Neuroimmune Alteration and Memory Decline in Aging Mice: The Role of Augmented Cellular Senescence [0.03%]
脂多糖诱导的小鼠神经免疫改变和记忆力下降:细胞衰老加剧的作用
Miracle K Nekabari,Benneth Ben-Azu,Bienose S Chijioke et al.
Miracle K Nekabari et al.
Flavonoid Rutin Reduces Intestinal Inflammation in an Experimental Model of Parkinson's Disease [0.03%]
flavonoids成分芸香素可通过实验减少帕金森病小鼠模型的肠道炎症
Livia Bacelar De Jesus,Annyta Fernandes Frota,Fillipe Mendes De Araújo et al.
Livia Bacelar De Jesus et al.
The enteric nervous system (ENS), a complex network of neurons and glial cells, is essential for maintaining intestinal homeostasis and is implicated in neurodegenerative diseases such as Parkinson's disease (PD). The gut-brain axis, modula...
Camphor-Induced Seizures in Rats Increase the Potency of Gamma Oscillations During the Ictal Period, A Component that may Lead to Refractoriness in Seizure Control [0.03%]
莰烷诱发的大鼠癫痫发作增加了惊厥期γ振荡的幅度,这是导致抗惊厥药疗效降低的因素之一
Priscille Fidelis Pacheco Hartcopff,Clarissa Araujo da Paz,Luciana Eiró Quirino et al.
Priscille Fidelis Pacheco Hartcopff et al.
Particularly in the evaluation of substances that can cause neuronal hyperexcitability, triggering refractoriness to antiepileptic drugs, this has always been of interest to science. This study investigated the neurobehavioral and electroco...
Decreased Length of Locus Coeruleus Norepinephrine Axons and Increased Amyloid Beta Pathology in Male APP/PS1 Mice During Protracted Abstinence From Alcohol [0.03%]
长期戒酒可降低APP / PS1小鼠蓝斑 noradrenergic轴突长度并增加β淀粉样蛋白病理学(英文)
Ivy J Z Garland,Shaydel Engel,Matthew Scalf et al.
Ivy J Z Garland et al.
Alzheimer’s disease (AD) is the leading cause of dementia and evidence suggests that alcohol, the most commonly used addictive substance, may increase AD risk. Locus coeruleus (LC) neurons are the primary source of norepinephrine in the br...
Role of LncRNA NEAT1 in Alzheimer's Disease: Pathophysiological Insights and Therapeutic Approaches [0.03%]
长非编码RNA NEAT1在阿尔茨海默病中的作用:病理生理学见解和治疗策略
Shreya,Gursimran Singh,Garry Hunjan et al.
Shreya et al.