Blunted Melatonin Circadian Rhythm in Parkinson's Disease: Express Bewilderment [0.03%]
帕金森病的褪黑素昼夜节律减弱：表达困惑
Areej Turkistani,Hayder M Al-Kuraishy,Ali I Al-Gareeb et al.
Areej Turkistani et al.
Melatonin (MTN) is a neuro-hormone released from the pineal gland. MTN secretion is regulated by different neuronal circuits, including the retinohypothalamic tract and suprachiasmatic nucleus (SCN), which are affected by light. MTN is neur...
Monomeric Amyloid Peptide-induced Toxicity in Human Oligodendrocyte Cell Line and Mouse Brain Primary Mixed-glial Cell Cultures: Evidence for a Neuroprotective Effect of Neurosteroid 3α-O-allyl-allopregnanolone [0.03%]
单体淀粉样肽诱导的人少突胶质细胞系和小鼠脑混合神经胶质原代培养中毒性作用：3α-O-烯丙基-别孕烷酮的神经营养保护效应证据
Nwife Getrude Okechukwu,Christian Klein,Hélène Jamann et al.
Nwife Getrude Okechukwu et al.
Amyloid-peptide (Aβ) monomeric forms (ABM) occurring in presymptomatic Alzheimer's disease (AD) brain are thought to be devoid of neurotoxicity while the transition/aggregation of ABM into oligomers is determinant for Aβ-induced toxicity ...
Retraction Note to: Topiramate Confers Neuroprotection Against Methylphenidate-Induced Neurodegeneration in Dentate Gyrus and CA1 Regions of Hippocampus via CREB/BDNF Pathway in Rats [0.03%]
有关：托吡酯通过CREB/Bdnf途径赋予托吡酯甲基苯丙胺诱导的海马齿状回和CA1区域神经退行性病变的神经保护作用的撤稿说明
Majid Motaghinejad,Manijeh Motevalian,Mohammad Abdollahi et al.
Majid Motaghinejad et al.
Retraction of Publication
Neurotoxicity research. 2024 Jul 25;42(4):36. DOI:10.1007/s12640-024-00714-2 2024
Retraction Note: Roflumilast Reduces Pathological Symptoms of Sporadic Alzheimer's Disease in Rats Produced by Intracerebroventricular Streptozotocin by Inhibiting NF-κB/BACE-1 Mediated Aβ Production in the Hippocampus and Activating the cAMP/BDNF Signalling Pathway [0.03%]
撤回 notice:罗氟司特通过抑制nf- κ b/bace-1介导的 hippocampus 中 aβ 生成及激活camp/bdnf信号通路来减轻脑室注射链脲佐菌素 sd 大鼠源散发性阿尔茨海默病的病理症状
Noorul Hasan,Saima Zameer,Abul Kalam Najmi et al.
Noorul Hasan et al.
Retraction of Publication
Neurotoxicity research. 2024 Jul 15;42(4):34. DOI:10.1007/s12640-024-00713-3 2024
FABP3 Induces Mitochondrial Autophagy to Promote Neuronal Cell Apoptosis in Brain Ischemia-Reperfusion Injury [0.03%]
FABP3通过诱导线粒体自噬促进脑缺血再灌注损伤的神经元细胞凋亡
Fang-Fang Zhong,Bo Wei,Guo-Xiang Bao et al.
Fang-Fang Zhong et al.
This study elucidates the molecular mechanisms by which FABP3 regulates neuronal apoptosis via mitochondrial autophagy in the context of cerebral ischemia-reperfusion (I/R). Employing a transient mouse model of middle cerebral artery occlus...
Cerebral White Matter Alterations Associated With Oligodendrocyte Vulnerability in Organic Acidurias: Insights in Glutaric Aciduria Type I [0.03%]
有机酸尿症中与少突胶质细胞脆弱性相关的脑白质改变：一型戊二酸血症中的见解
Eugenia Isasi,Moacir Wajner,Juliana Avila Duarte et al.
Eugenia Isasi et al.
The white matter is an important constituent of the central nervous system, containing axons, oligodendrocytes, and its progenitor cells, astrocytes, and microglial cells. Oligodendrocytes are central for myelin synthesis, the insulating en...
The Role of Excitotoxicity, Oxidative Stress and Bioenergetics Disruption in the Neuropathology of Nonketotic Hyperglycinemia [0.03%]
非酮症高甘氨酸血症的神经病理学中兴奋性毒性、氧化应激和生物能量紊乱的作用
Guilhian Leipnitz,Jaqueline Santana da Rosa,Moacir Wajner
Guilhian Leipnitz
Nonketotic hyperglycinemia (NKH) is an inherited disorder of amino acid metabolism biochemically characterized by the accumulation of glycine (Gly) predominantly in the brain. Affected patients usually manifest with neurological symptoms in...
FOXA1 Suppresses Endoplasmic Reticulum Stress, Oxidative Stress, and Neuronal Apoptosis in Parkinson's Disease by Activating PON2 Transcription [0.03%]
FOXA1通过激活PON2转录抑制帕金森病中的内质网应激、氧化应激和神经元凋亡
Jiahui Liu,Yu Fan,Jinyu Chen et al.
Jiahui Liu et al.
Endoplasmic reticulum (ER) stress and oxidative stress (OS) are often related states in pathological conditions including Parkinson's disease (PD). This study investigates the role of anti-oxidant protein paraoxonase 2 (PON2) in ER stress a...
PEG300 Protects Mitochondrial Function By Upregulating PGC-1α to Delay Central Nervous System Oxygen Toxicity in Mice [0.03%]
PEG300通过上调PGC-1α保护线粒体功能以延缓小鼠中枢神经系统氧毒性损伤
Xin Li,Yue Shen,Dan Li et al.
Xin Li et al.
Central nervous system oxygen toxicity (CNS-OT) is a complication of hyperbaric oxygen (HBO) treatment, with limited prevention and treatment options available. In this study, we aimed to explore the effect of polyethylene glycol 300 (PEG30...
Assessment of Hippocampal-Related Behavioral Changes in Adolescent Rats of both Sexes Following Voluntary Intermittent Ethanol Intake and Noise Exposure: A Putative Underlying Mechanism and Implementation of a Non-pharmacological Preventive Strategy [0.03%]
评估自愿间歇性摄入酒精和噪声暴露对两性青春期大鼠海马相关行为改变：潜在作用机制及非药物预防策略的实施
G E Buján,L D&#x;Alessio,H A Serra et al.
G E Buján et al.
Ethanol (EtOH) intake and noise exposure are particularly concerning among human adolescents because the potential to harm brain. Unfortunately, putative underlying mechanisms remain to be elucidated. Moreover, implementing non-pharmacologi...