Drug-resistant tuberculosis profiles among patients presenting at the antituberculosis center of Brazzaville, Republic of Congo [0.03%]
刚果布拉柴维尔抗结核中心患者耐药结核病特征分析
Breli Bonheur Ngouama,Jean Claude Djontu,Darrel Ornelle Elion Assiana et al.
Breli Bonheur Ngouama et al.
Background: WHO strategy to end Tuberculosis (TB) calls for drug susceptibility testing of Mycobacterium tuberculosis (MTB) for all patients, in high TB burden settings. Thus, this study aimed to investigate the MTB drug ...
A pathogen-detection's odyssey in a case of skull base osteomyelitis: Land ahoy! [0.03%]
颅底骨髓炎病例中的病原体检测历程：“发现陆地！”
Laurenz Althaus,Insa Joost,Katharina Schaumann et al.
Laurenz Althaus et al.
Background: Skull base osteomyelitis (SBO) is a severe disease not only because of its rapid progression and its high mortality: diagnosis and treatment are often protracted and in more than 30% of cases no causative path...
Is neutropenia still the main risk factor for invasive aspergillosis? A contemporary university hospital retrospective cohort of invasive aspergillosis in neutropenic and non-neutropenic patients [0.03%]
中性粒细胞减少症仍是侵袭性曲霉病的主要风险因素吗？一项当代大学医院回顾性队列研究：中性粒细胞减少症和非中性粒细胞减少症患者的侵袭性曲霉病
Andrea Gutiérrez-Villanueva,Itziar Diego-Yagüe,Isabel Gutiérrez-Martín et al.
Andrea Gutiérrez-Villanueva et al.
Introduction: In times of mold active prophylaxis, invasive aspergillosis (IA) epidemiology is evolving. Presentation in non-neutropenic may differ from neutropenic. We investigated the cases of IA in our center with a fo...
Long COVID clinical evaluation, research and impact on society: a global expert consensus [0.03%]
长期新冠的临床评估、研究及其对社会的影响：全球专家共识
Andrew G Ewing,David Joffe,Svetlana Blitshteyn et al.
Andrew G Ewing et al.
Background: Long COVID is a complex, heterogeneous syndrome affecting over four hundred million people globally. There are few recommendations, and no formal training exists for medical professionals to assist with clinic...
Clinical and Microbiological characteristics of patients with ceftazidime/avibactam-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae strains [0.03%]
碳青霉烯耐药产KPC型肺炎克雷伯菌的临床及微生物特征分析
Szu-Yu Liu,Sheng-Hua Chou,Chien Chuang et al.
Szu-Yu Liu et al.
Background: Ceftazidime/avibactam (CZA)-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae has emerged, typically due to mutations in the blaKPC gene. This study aimed to investigate the clinical ...
Prevalence of antimalaria drug resistance-conferring mutations associated with sulphadoxine-pyrimethamineine-resistant Plasmodium falciparum in East Africa: a systematic review and meta-analysis [0.03%]
东非恶性疟原虫磺胺多辛-甲氧苄氨嘧啶耐药相关抗疟基因突变的患病率：系统评价和荟萃分析
Wagaw Abebe,Agenagnew Ashagre,Tadesse Misganaw et al.
Wagaw Abebe et al.
Background: The emergence and spread of drug resistance to antimalarial drugs pose a severe threat to effective malaria control and treatment. Although sulfadoxine-pyrimethamine resistance is well-documented, it is still ...
Activity of imipenem/relebactam against KPC-producing Klebsiella pneumoniae and the possible role of Ompk36 mutation in determining resistance: an Italian retrospective analysis [0.03%]
美罗培南雷巴坦对产KPC酶肺炎克雷伯菌的体外活性及OmpK36突变在耐药性中的作用：一项意大利回顾性研究
Emanuele Palomba,Agnese Comelli,Francesca Saluzzo et al.
Emanuele Palomba et al.
Background: Antimicrobial resistance in Enterobacterales represents a substantial threat in modern clinical practice and the collection of data on the efficacy of new molecules is of paramount importance. Our study aimed ...
Novel strategies for vancomycin-resistant Enterococcus faecalis biofilm control: bacteriophage (vB_EfaS_ZC1), propolis, and their combined effects in an ex vivo endodontic model [0.03%]
万古霉素耐药粪肠球菌生物被膜控制的新策略：噬菌体（vB_EfaS_ZC1）、蜂胶及其联合应用的离体牙髓模型效应研究
Toka A Hakim,Bishoy Maher Zaki,Dalia A Mohamed et al.
Toka A Hakim et al.
Background: Endodontic treatment failures are predominantly attributed to Enterococcus faecalis (E. faecalis) infection, a Gram-positive coccus. E. faecalis forms biofilms, resist multiple antibiotics, and can withstand e...
Genomic characteristics, virulence potential, antimicrobial resistance profiles, and phylogenetic insights into Nocardia cyriacigeorgica [0.03%]
诺卡氏菌基因组特性、毒力潜力、抗菌药物耐药性特征及系统发育见解
Chen Yang,Yue-Xin Zheng,Hong-Yi Gu et al.
Chen Yang et al.
Background: Nocardia cyriacigeorgica, an opportunistic pathogen, is increasingly implicated in human infections. This pathogen predominantly causes pulmonary infections, leading to acute, subacute, or chronic necrotizing ...
Connie T Y Xie,Samantha Martinez,Ceylon V Simon et al.
Connie T Y Xie et al.
Background: Stratified antibiograms are recommended to guide empiric clinical treatment. However, which strata to focus on, the limited number of isolates in identified strata, and the heavy associated workload all pose c...