Clinical features of nontuberculous mycobacteria and diagnosis with nanopore targeted sequencing: a retrospective cohort study [0.03%]
NTM临床特征及纳米孔靶向测序诊断:回顾性队列研究
Xingyu Liu,Tianzhen Wang,Yicheng Guo et al.
Xingyu Liu et al.
Background: Diagnosing pulmonary non-tuberculous mycobacterial (NTM) disease remains challenging, not only because its clinical manifestations often overlap with those of tuberculosis (TB), but also because its symptoms a...
Specimen-specific distribution of multidrug-resistant organisms and its association with glycemic control in adults with diabetes: a retrospective clinical microbiology study in southern Taiwan [0.03%]
糖尿病成人多重耐药菌分布及其与血糖控制相关性的回顾性临床微生物学研究
Jung-Sheng Chen,Mei-Yin Chou,Siang-Ru Huang et al.
Jung-Sheng Chen et al.
Background: Patients with diabetes mellitus are susceptible to bacterial infections and may be exposed to repeated or prolonged antimicrobial therapy, which can increase the risk of multidrug-resistant organism (MDRO)-pos...
Incidence, mortality and risk factors of invasive pulmonary aspergillosis in critically ill patients during the COVID-19 era: a global systematic review and meta-analysis [0.03%]
COVID-19疫情期间重症患者侵袭性肺曲霉病的发病、死亡率及危险因素的全球系统评价和meta分析
Zijing Zhou,Bin Luo,Xiwen Zhang et al.
Zijing Zhou et al.
Background: Invasive pulmonary aspergillosis (IPA) represents a growing threat to critically ill patients, with mortality rates exceeding 50%. The burden of IPA has been exacerbated during the COVID-19 era due to prolonge...
Effectiveness of cefazolin versus anti-staphylococcal β-lactam for treating methicillin-susceptible Staphylococcus aureus pneumonia in critically ill patients admitted to intensive care units: a multicenter cohort study [0.03%]
甲氧西林敏感金黄色葡萄球菌肺炎患者使用头孢唑林与抗葡萄球菌β-内酰胺类药物治疗效果的多中心队列研究:一项多中心队列研究
Sufyan M Alomair,Khalid Al Sulaiman,Aisha Alharbi et al.
Sufyan M Alomair et al.
Introduction: Critically ill patients carry a high risk of infections and related complications, which significantly increase mortality. For patients with confirmed methicillin-susceptible Staphylococcus aureus (MSSA) pne...
Rare emergence of delamanid resistance in multidrug-/rifampicin-resistant tuberculosis patients receiving delamanid-containing regimens: a prospective multicentric study in China [0.03%]
中国多中心前瞻性研究中应用德拉马尼方案治疗的耐多药/利福平耐药肺结核患者中德拉马尼耐药罕见出现:一项前瞻性多中心研究
Wei Shu,Qingshan Cai,Yuping Huang et al.
Wei Shu et al.
Background: Delamanid (DLM) is a promising drug recommended for treatment of multidrug-/rifampicin-resistant tuberculosis (MDR/RR-TB). However, there are very little data about the emergence of drug resistance in patients...
Clinical characteristics and temporal trends of meropenem and piperacillin/tazobactam heteroresistance in Pseudomonas aeruginosa isolates [0.03%]
美罗培南和哌拉西林他唑巴坦对铜绿假单胞菌异质性耐药的临床特征及时间趋势分析
Yali Fan,Huilan Li,Xiaoyue Liang et al.
Yali Fan et al.
Background: Heteroresistance (HR) to commonly used anti-pseudomonal agents in Pseudomonas aeruginosa has been reported in cross-sectional epidemiological surveys; however, longitudinal studies investigating the long-term ...
Investigation of atypical microbial agents in patients with sterile pyuria [0.03%]
对无菌脓尿患者进行非典型微生物病原体检测的研究
Elif Seren Tanrıverdi,Yusuf Yakupoğulları,Ayten Gündüz et al.
Elif Seren Tanrıverdi et al.
Background: To determine the frequency of microbial DNA detection in patients with sterile pyuria and evaluate the association of leukocyte count and leukocyte esterase (LE) test results with physicians' treatment decisio...
Convergent evolution of ST2 and ST164 mediates dissemination of the blaNDM-1/blaOXA-23 profile in Acinetobacter baumannii [0.03%]
ST2和ST164的趋同进化介导了鲍曼不动杆菌中blaNDM-1/blaOXA-23谱型的传播
Ren Liu,Guilin Jin,Feng Yu et al.
Ren Liu et al.
Background: The convergence of the potent carbapenemase genes blaNDM-1 and blaOXA-23 in carbapenem-resistant Acinetobacter baumannii (CRAB) poses a critical threat. However, the dissemination patterns and evolutionary dri...
Efficacy and safety of intravenous combined with aerosolized colistimethate sodium for carbapenem-resistant organism-induced pneumonia: a retrospective study [0.03%]
卡贝坦耐药菌所致肺炎患者使用注射及雾化重组硫酸多粘菌素治疗的有效性和安全性:一项回顾性研究
Ji Liu,Wei Wang,Xun Deng et al.
Ji Liu et al.
Background: Polymyxins are regarded as the last-resort antibiotics for treating resistant Gram-negative bacteria. Colistimethate sodium (CMS) is commonly used for carbapenem-resistant organism (CRO)-induced pulmonary infe...
A longitudinal analysis of Clostridioides difficile virulence profiles across three geographic regions in Israel (2020-2022) [0.03%]
以色列(2020-2022)三个地理区域的艰难梭菌毒力谱系纵向分析
Orna Schwartz,Avi Peretz,Maya Azrad
Orna Schwartz
Background: Clostridioides difficile infection (CDI) is one of the leading infectious diarrhea worldwide. C. difficile pathogenicity is mediated by various virulence factors, including toxins and biofilm formation. This s...