Antimicrobial susceptibility of Legionella gormanii: species-specific ECOFFs, distinct MICs for rifampin versus Legionella pneumophila [0.03%]
葛兰氏 legionalla 的抗菌活性：物种特异性的 ecoff 以及红霉素素对 legioella pneumophla 米克值的差异
Jun-Wei Xu,Yuan-Tong He,Xiao-Yong Zhan
Jun-Wei Xu
Background: Legionella gormanii (L. gormanii) is an emerging pathogen causing legionellosis, yet it is much less studied than the predominant species, L. pneumophila. Clinical treatment guidelines for legionellosis are pr...
Impact of the COVID-19 pandemic on neonatal sepsis: epidemiological shifts, antibiotic resistance patterns, and pathogen profiles in a tertiary referral hospital [0.03%]
新冠肺炎疫情对新生儿败血症的影响：三级转诊医院的流行病学变化、抗生素耐药模式和病原体特征
Leyla Sahebi,Hossein Dalili,Mamak Shariat et al.
Leyla Sahebi et al.
Background: Neonatal sepsis is a major cause of morbidity and mortality worldwide. The COVID-19 pandemic has influenced its epidemiology, altering pathogen distribution and antimicrobial resistance patterns, necessitating...
Efflux pumps positively contribute to rifampin resistance in rpoB mutant Mycobacterium tuberculosis [0.03%]
外排泵可促进rpoB突变结核分枝杆菌的利福平耐药性
Fanrong Meng,Yuanjin Chen,Zeyou Wei et al.
Fanrong Meng et al.
Background: While several recent studies have documented the importance of efflux pumps as mediators of rifampin (RIF) resistance, it remains uncertain which efflux pumps play major roles in rifampin-resistant Mycobacteri...
The bacterial etiology and antimicrobial susceptibility of lower respiratory tract infections in Vietnam [0.03%]
越南下呼吸道感染的细菌病原学和抗微生物敏感性
Tran Thi Ngoc Dung,Chau Vinh,Pham Hong Anh et al.
Tran Thi Ngoc Dung et al.
Background: Lower respiratory tract infection (LRTI) remains the leading infectious cause of morbidity and mortality globally. Key bacterial pathogens include Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pn...
Detection of hypervirulent Klebsiella pneumoniae (hvKp) strains directly from spiked blood cultures using a commercial Loop-Mediated isothermal amplification (LAMP) assay [0.03%]
使用商业环介导等温扩增(LAMP)试验直接从感染样本的血培养中检测肺炎克雷伯氏菌( hvKp )毒株
Domingo Fernández Vecilla,Jorge Rodríguez Grande,Nuria Fraile Valcárcel et al.
Domingo Fernández Vecilla et al.
Background: Hypervirulent K. pneumoniae (hvKp) strains are characterized by their enhanced ability to evade immune responses and disseminate systemically. Rapid identification of hvKp strains is critical for guiding clini...
Dissemination of a IncHI2A plasmid co-harboring the mcr-9 and blaNDM-1 genes in Israeli hospitals [0.03%]
携载mcr-9和blaNDM-1基因的IncHI2A质粒在以色列医院中的播散
Amos Adler,Stefany Ayala-Montaño,Mark V Assous et al.
Amos Adler et al.
The mcr-9 allele is typically located on IncHI2 type plasmids, but there are only few reports describing the co-occurrence of the blaNDM gene on the same plasmid. Our aims were to describe the spread of an IncHI2A plasmid harboring both the...
Identification and preclinical efficacy evaluation of two lytic bacteriophages targeting highly virulent and multidrug-resistant Klebsiella pneumoniae [0.03%]
两种裂解性噬菌体对高毒力多重耐药肺炎克雷伯菌的鉴定及临床前疗效评估
Ai Guo,Dianbao Zuo,Li Shi et al.
Ai Guo et al.
Background: The emergence of MDR K. pneumoniae poses a critical challenge in treating respiratory-associated pneumonia. Bacteriophages are promising antibiotic alternatives with unique features. This study aimed to isolat...
Whole-genome recombination and dynamic accessory genomes drive the phenotypic diversity of Mycobacterium abscessus subspecies [0.03%]
整个基因组的重组和动态辅助基因组驱动了鸟分支菌亚种的表现型多样性
Yu Chen,Rong Bao,Na Li et al.
Yu Chen et al.
Background: Mycobacterium abscessus (Mab) is a multidrug-resistant bacterial pathogen capable of causing widespread infections, often with a poor prognosis in susceptible populations. Mab comprises three distinct subspeci...
Characteristics of Neisseria meningitidis isolated from patients with urogenital infection in a region of China [0.03%]
中国某地区泌尿生殖道感染患者中分离的脑膜炎奈瑟菌的特征分析
Qinghui Xie,Yang Yang,Wenwen Xu et al.
Qinghui Xie et al.
Background: Neisseria meningitidis (Nm), traditionally recognized as a nasopharyngeal commensal causing invasive meningococcal disease (IMD), has recently emerged as an etiological agent of urethritis worldwide, with spor...
Bacteriological profile and antimicrobial resistance in sepsis cases in intensive care units in Lubumbashi: challenges and perspectives [0.03%]
卢邦巴希重症监护病房中败血症病例的细菌学特征及抗微生物药物耐药性：挑战与展望
Michel Muteya Manika,Aristophane Koffi Tano,Liévin Kalala Kapend&#x;a et al.
Michel Muteya Manika et al.
Background: Sepsis remains a major public health challenge, leading to high mortality and morbidity rates, particularly among low-income populations such as those in sub-Saharan Africa. Its management is complicated by th...