Current infectious disease management challenges in inborn errors of immunity [0.03%]
先天性免疫缺陷的当前传染病管理挑战
Shuwei Zheng,David M Lowe
Shuwei Zheng
Inborn errors of immunity (IEIs) are a frequently underdiagnosed group of disorders, with infectious complications posing significant clinical challenges. Recognizing atypical presentations of common infections and the presence of rare oppo...
Diagnostic importance of Treponema pallidum Tp0971 in the serological assessment of treatment efficacy for syphilis [0.03%]
Tp0971蛋白在梅毒治疗效果血清学评估中的诊断价值研究
Xiaohong Zhang,Jiangchen Yao,Han Jiang et al.
Xiaohong Zhang et al.
Over the last twenty years, there has been a global resurgence of infections caused by Treponema pallidum subsp. pallidum (T. pallidum), the bacterium responsible for syphilis. Presently, the T. pallidum IgG chemiluminescence immunoassay (C...
Bactericidal activity and Inhibition of levofloxacin-induced resistance by antibacterial combination against hypervirulent Klebsiella pneumoniae [0.03%]
左氧氟沙星诱导的高毒力肺炎克雷伯菌耐药性的抗菌组合的杀菌活性及抑制作用
Alimire Aimaiti,Qingqing Xu,Li Ding et al.
Alimire Aimaiti et al.
Background: Hypervirulent Klebsiella pneumoniae (hvKP) infection is characterized by its potential severity and metastatic propensity, underlying the importance to employ bactericidal treatment promptly for infection sour...
Resistance profile and influence factors of carbapenem-resistant Klebsiella pneumoniae (CRKP) causing infections in China: a systematic review and meta-analysis [0.03%]
中国碳青霉烯类耐药肺炎克雷伯菌的耐药谱及影响因素：系统综述和meta分析
Xiaolu Yang,Zhenghao Lou,Xinrui Wang et al.
Xiaolu Yang et al.
The prevalence of carbapenem-resistant Klebsiella pneumoniae (CRKP) infections has surged in China over the past decade, posing a significant public health concern. However, comprehensive data on CRKP antimicrobial resistance patterns and t...
Heteroresistance is associated with mutations during low concentration of tigecycline therapy in multiple-resistant Klebsiella pneumoniae [0.03%]
低浓度替加环素治疗期间多重耐药肺炎克雷伯菌的异质性耐药及突变研究
Qiaoyu Zhang,Linwen Zheng,Lirong Wen et al.
Qiaoyu Zhang et al.
Background: Heteroresistance can lead to treatment failure and has brought a rigorous challenge to clinical laboratories for detecting them. The aim of this study was to investigate the potential for tigecycline-susceptib...
Evaluation of SAT-Candida: a rapid RNA-based isothermal amplification assay for detection and identification of Candida spp. in vaginal specimens [0.03%]
评估SAT-念珠菌：一种快速的基于RNA的等温扩增检测和鉴定阴道标本中念珠菌的方法
Loukaiyi Lu,Yisheng Chen,Qiang Wang et al.
Loukaiyi Lu et al.
Background: This study evaluated the performance of the simultaneous amplification and testing (SAT) assay for detecting common Candida species in vaginal specimens compared with culture (gold standard) at the Obstetrics ...
Biocide, antifungal susceptibility and virulence characteristics of Clade 1 Candidozyma auris strains [0.03%]
克罗恩病1型 candidozyma auris 株的杀菌、抗真菌敏感性及毒力特征
Ayşe Kalkanci,Sidre Erganis,Elif Ayça Sahin et al.
Ayşe Kalkanci et al.
Background: Candidozyma auris is an emerging multidrug-resistant fungal pathogen responsible for nosocomial outbreaks worldwide. In addition to antifungal resistance, its ability to persist in the hospital environment and...
Innowave MTB/RIF/INH facilitates timely and accurate diagnosis of multiple-drug resistant tuberculosis as a near POCT technique: a multicenter prospective on-site performance evaluation study [0.03%]
一项多中心现场性能评价研究：作为快速分子检测技术，Innowave MTB/RIF/INH可及时准确诊断耐多药结核病
Fen Wang,Long Cai,Zhongfeng Cui et al.
Fen Wang et al.
Background: Many rifampicin (RIF)-resistant (RR) tuberculosis (TB) patients remain sensitive to isoniazid (INH), which challenges the strategy of using RR as an instant indicator of multiple-drug resistance tuberculosis (...
Antimicrobial susceptibility of Legionella gormanii: species-specific ECOFFs, distinct MICs for rifampin versus Legionella pneumophila [0.03%]
葛兰氏 legionalla 的抗菌活性：物种特异性的 ecoff 以及红霉素素对 legioella pneumophla 米克值的差异
Jun-Wei Xu,Yuan-Tong He,Xiao-Yong Zhan
Jun-Wei Xu
Background: Legionella gormanii (L. gormanii) is an emerging pathogen causing legionellosis, yet it is much less studied than the predominant species, L. pneumophila. Clinical treatment guidelines for legionellosis are pr...
Impact of the COVID-19 pandemic on neonatal sepsis: epidemiological shifts, antibiotic resistance patterns, and pathogen profiles in a tertiary referral hospital [0.03%]
新冠肺炎疫情对新生儿败血症的影响：三级转诊医院的流行病学变化、抗生素耐药模式和病原体特征
Leyla Sahebi,Hossein Dalili,Mamak Shariat et al.
Leyla Sahebi et al.
Background: Neonatal sepsis is a major cause of morbidity and mortality worldwide. The COVID-19 pandemic has influenced its epidemiology, altering pathogen distribution and antimicrobial resistance patterns, necessitating...