Genomic epidemiology and aztreonam-avibactam resistance mechanisms of Proteus mirabilis in china: an eight-year retrospective study [0.03%]
中国阴沟肠杆菌的基因组流行病学及 AZT-AVI 耐药机制：一项八年的回顾性研究
Jingyi Guo,Chengjin Wu,Xinyan Tang et al.
Jingyi Guo et al.
Background: Proteus mirabilis has emerged as an important multidrug-resistant opportunistic pathogen, with the production of metallo-β-lactamases (MBLs) being a major contributor to its broad-spectrum resistance. Althoug...
Coexistence with Staphylococcus aureus modulates the virulence and antibiotic resistance of Pseudomonas aeruginosa [0.03%]
与金黄色葡萄球菌共存可调节绿脓杆菌的毒力和抗生素抗性
Zeinab M Helal,Soha Lotfy Elshaer,Mohammed El-Mowafy et al.
Zeinab M Helal et al.
Background: In this study, we were aimed to investigate the impact of co-cultures of different bacterial species on bacterial antibiotic resistance and virulence. ...
Clinical patterns, species-specific correlations, and therapeutic outcomes of nocardiosis in immunocompetent individuals: a systematic analysis based on literature [0.03%]
免疫功能正常的诺卡菌病患者的临床模式、物种特异性相关性及治疗结局：基于文献的系统分析
Le Lu,Dongyi Wang,Muzi Li et al.
Le Lu et al.
Background: Nocardiosis, traditionally an opportunistic infection, lacks comprehensive characterization in immunocompetent individuals. This study aimed to describe and analyze the demographics, clinical features, and out...
Characterization using ultra-deep sequencing of the intra-host distribution of the mutations associated with H. pylori antibiotic resistance [0.03%]
利用超深度测序表征 Hp抗生素耐药性相关突变的宿主体内分布特征
Laura Chaufour,Alexandra Herve,Birama Ndiaye et al.
Laura Chaufour et al.
Introduction: Helicobacter pylori is a slow-growing, gram-negative strictly pathogenic bacterium, which colonizes the stomachs of half the global population and is responsible for gastritis, peptic ulcer and even adenocar...
The impact of the timing of mNGS-guided antibiotic adjustment on clinical outcomes in ICU patients with severe community-acquired pneumonia: a retrospective study [0.03%]
关于重症社区获得性肺炎患者mNGS引导下的抗生素调整时机对临床结局影响的回顾性研究
Yong Sun,Kai Guo,Jing Tang et al.
Yong Sun et al.
Background: Severe community-acquired pneumonia (SCAP) remains a major cause of intensive care unit (ICU) admission and mortality. Prompt pathogen identification and timely administration of appropriate antimicrobial ther...
Clinical impact of altered gut microbiota and metabolite profiles on mortality in patients with candidemia: a prospective observational pilot cohort study [0.03%]
肠道菌群和代谢产物异常对念珠菌血症患者死亡率影响的前瞻性观察队列研究
Soo Hyun Park,Seung Min Park,Jin Woong Suh et al.
Soo Hyun Park et al.
Background: The gut microbiota plays an important role in defending against infectious diseases. However, data on the clinical implications of the microbiome profiles in patients with candidemia remain limited. In this st...
Pathogen-specific IgE-reactive cytosolic allergenic epitopes of Aspergillus fumigatus for immunodiagnostic/immunotherapeutic applications against allergic aspergillosis [0.03%]
用于免疫诊断/免疫治疗抗过敏性曲霉病的烟曲霉特异性IgE反应性胞浆变应原表位
Priya Koundal,Sunita Manhas,Shahbaz Aman et al.
Priya Koundal et al.
Aspergillus fumigatus is a significant fungal pathogen responsible for allergic bronchopulmonary aspergillosis (ABPA), a global respiratory disease characterized by high morbidity and mortality. Accurate diagnosis of ABPA remains challengin...
Fatal multi-drug-resistant gram-negative bacterial pneumonia among adults hospitalized àt Mulago National Referral Hospital, Uganda: an autopsy study [0.03%]
乌干达马拉戈国家转诊医院成人多药耐药革兰氏阴性细菌肺炎死亡病例的尸检研究
Wellington Mutumba,Henry Kajumbula,Robert Lukande et al.
Wellington Mutumba et al.
Background: Pneumonia, responsible for three million deaths annually worldwide, remains a leading cause of death from hospital-acquired infections. Unfortunately, treatment in most cases is empirical and not based on micr...
Transient AdeABC-mediated eravacycline resistance in carbapenem-resistant Acinetobacter baumannii ST2: a mutation-independent efflux pump adaptation [0.03%]
碳青霉烯耐药的阿氏不动杆菌ST2株系中AdeABC介导的埃拉瓦西林瞬时耐药性：独立于突变的外排泵适应机制
Xu Yang,Nanhao He,Anwarul Haque et al.
Xu Yang et al.
Cross-sectional hospital-based investigation on clinical characteristics of pediatric Group A Streptococcus isolates in a Beijing hospital from 2014 to 2023 [0.03%]
2014年至2023年北京某医院儿科A群链球菌临床特征横断面研究
Luwei Wang,Zhiyong Lyu
Luwei Wang
Background: Group A Streptococcus (GAS) is a major bacterial pathogen associated with diverse clinical diseases. Despite its general susceptibility to β-lactam antibiotics, GAS outbreaks remain a significant global healt...