Within-host mechanisms of resistance evolution in polymyxin B-resistant Klebsiella pneumoniae without prior exposure [0.03%]
无先前暴露情况下肺炎克雷伯菌多粘菌素B耐药的体内进化机制
Jun Li,Yuyao Wang,Haolan Wang et al.
Jun Li et al.
Unlocking p-coumaric acid's potential against biofilm-forming extensively drug-resistant Acinetobacter baumannii: in vitro and in vivo study [0.03%]
对生物膜型广泛耐药阿维塔菌活性的对羟苯甲酸的体内和体外研究
Noha A Attia,Ahmed A Abdelaziz,Fatma I Sonbol et al.
Noha A Attia et al.
Background: The global rise of extensively drug-resistant Acinetobacter baumannii, particularly biofilm-forming strains, has drastically limited treatment options and created an urgent need for novel therapies to restore ...
Charcoal agar interference in antibiotic susceptibility testing of Bordetella pertussis: evaluation and alternative methodologies [0.03%]
活性炭琼脂对百日咳博德特氏菌药敏试验的干扰及替代方法评价
Wei Wang,Lin Wang,Kaichong Jiang et al.
Wei Wang et al.
An ultra-sensitive cell-free DNA-based diagnostic assay for Tuberculous pleurisy utilizing the CRISPR-Cas13a system [0.03%]
基于CRISPR-Cas13a系统的结核性胸膜炎无细胞DNA超灵敏诊断试验
Weicong Ren,Mengjie Yang,You Zhou et al.
Weicong Ren et al.
Background: Tuberculous pleurisy (TP), a predominant form of extrapulmonary tuberculosis, presents significant diagnostic challenges attributable to the paucibacillary nature of pleural effusion (PE) specimens. Cell-free ...
Species-dependent in polymyxin B heteroresistance: genomic insights into adaptive evolution in Enterobacteriaceae [0.03%]
多黏菌素B种依赖性异耐药性：肠杆菌科适应性进化基因组学见解
Hui Zhang,Linna Xu,Xiaofen Mo et al.
Hui Zhang et al.
Background: Polymyxin heteroresistance poses a growing challenge in antimicrobial resistance management, yet its epidemiological features and molecular basis across different bacterial species and environments remain poor...
Comparative evaluation of Anyplex™ MTB/NTM, Xpert MTB/RIF ultra, culture, and microscopy for the diagnosis of pediatric tuberculosis using gastric aspirates [0.03%]
胃吸出物中儿童结核病的诊断：基于AnyplexTM MTB / NTM、Xpert MTB / RIF ultra、培养和显微镜检查的比较评估研究
Matúš Dohál,Věra Dvořáková,Michaela Hromádková et al.
Matúš Dohál et al.
Background: Paediatric tuberculosis (TB) diagnosis remains a challenge due to the paucibacillary nature of the disease, resulting in 51.00% of TB cases remaining undiagnosed, rising to 58% in children under five years of ...
Analysis of the evolution mechanism of in-host drug resistance of Klebsiella pneumoniae during treatment with tigecycline, eravacycline and Polymyxin B [0.03%]
碳氢霉烯类、艾拉 cycline 和多黏菌素 B 治疗期间肺炎克雷伯氏菌宿内耐药性演变机制分析
Jianhua Fang,Miao Deng,Zhongmin Li et al.
Jianhua Fang et al.
Infections caused by Carbapenem-Resistant Klebsiella pneumoniae (CRKP) have become a serious threat to global public health. We reported fatal infections associated with Klebsiella pneumoniae (KP) and revealed the evolution of in-host drug ...
Airborne Mycobacterium tuberculosis inactivated by advanced photohydrolysis technology [0.03%]
运用高级光水解技术使空气中的结核杆菌失活
Jennifer E Peel,Alyssa A Varghese,Reina N Paez et al.
Jennifer E Peel et al.
Tuberculosis is a respiratory infectious disease that persists worldwide, largely due to the robustness and ease of dissemination of its causative agent, Mycobacterium tuberculosis. To mitigate the spread of infection, various measures have...
Emergence of hypervirulent ESBL-producing Klebsiella pneumoniae with high virulence and antibiotic resistance in Southwest of Iran [0.03%]
伊朗西南部高毒力和耐药性的产ESBL肺炎克雷伯菌的出现
Fatemeh Sefati,Seyed Abdolmajid Khosravani,Mohammad Amin Ghatee et al.
Fatemeh Sefati et al.
Evaluation of diagnostic performance of comprehensive respiratory virus panel: comparison of next-generation-sequencing to real-time polymerase chain reaction for detection of respiratory viruses [0.03%]
综合呼吸道病原体检测试剂盒诊断性能评价：下一代测序检测方法与实时荧光定量PCR的比较
Sojin Lee,Yoonjung Kim,Kyung-A Lee
Sojin Lee
Background: Respiratory viral infections remain a global health concern, particularly among children, the elderly, and immunocompromised individuals. Although real-time polymerase chain reaction (RT-PCR) is the diagnostic...