Poor efficacy of the combination of clarithromycin, amikacin, and cefoxitin against Mycobacterium abscessus in the hollow fiber infection model [0.03%]
克拉维林、阿米卡星和头孢西丁联合对黏液鲍曼不动杆菌感染的疗效有限：空腔纤维感染模型研究
Etienne Vignaud,Sylvain Goutelle,Charlotte Genestet et al.
Etienne Vignaud et al.
Background: Mycobacterium abscessus (MABS) causes difficult-to-treat pulmonary and extra-pulmonary infections. A combination therapy comprising amikacin, cefoxitin, and a macrolide agent is recommended, but its antimicrob...
Polyp and tumor microenvironment reprogramming in colorectal cancer: insights from mucosal bacteriome and metabolite crosstalk [0.03%]
结直肠癌中肠道息肉及肿瘤微环境的重塑：来自黏膜菌群和代谢物互作的研究启示
Hadi Feizi,Hossein Samadi Kafil,Andrey Plotnikov et al.
Hadi Feizi et al.
Background: Highly frequent colorectal cancer (CRC) is predicted to have 3.2 million novel cases by 2040. Tumor microenvironment (TME) bacteriome and metabolites are proposed to be involved in CRC development. In this reg...
Emergence and polyclonal dissemination of NDM-5/OXA-181 carbapenemase-producing Escherichia coli in the French Indian Ocean territories [0.03%]
法属印度洋地区NDM-5/OXA-181碳青霉烯耐药肠杆菌科细菌的出现及多克隆传播
Thibaut Vedani,Matthieu Pot,Thomas Garrigos et al.
Thibaut Vedani et al.
Aim: Located in the Southwest Indian Ocean area (SIOA), the two French overseas territories (FOTs) of Reunion and Mayotte islands are heavily impacted by antimicrobial resistance. The aim of this study was to investigate ...
Martin Martinot,Shu Shun Li,Catherine Farnarier et al.
Martin Martinot et al.
We describe pulmonary cryptococcosis in a 28-year-old previously healthy man. Exhaustive immunological investigations revealed a primary NK cell deficiency associated with a secondary impaired anti-Cryptococcus CD8 lymphocyte response and t...
Characteristics and spatiotemporal changes in phenotypes and genotypes of extended-spectrum β-lactamases in Escherichia coli isolated from bloodstream infections in China from 2014 to 2021 [0.03%]
我国2014-2021年临床血流感染大肠埃希菌产超广谱β内酰胺酶的分子特征及时空变化规律分析
Sayyed Salman,Hao Xu,Yunbo Chen et al.
Sayyed Salman et al.
Objective: To examine the characteristics and spatiotemporal changes in the phenotypes and genotypes of extended-spectrum β-lactamases (ESBLs) in Escherichia coli strains isolated from bloodstream infections (BSIs) acros...
Comparative In vitro antibacterial activity of nemonoxacin and other fluoroquinolones in correlation with resistant mechanisms in contemporary methicillin-resistant Staphylococcus aureus blood isolates in Taiwan [0.03%]
新莫西星与其他氟喹诺酮类对台湾地区当代耐甲氧西林金黄色葡萄球菌血流分离株的体外抗菌活性及与耐药机制的相关性比较研究
Pao -Yu Chen,Mao-Wang Ho,Po-Liang Lu et al.
Pao -Yu Chen et al.
Background: Nemonoxacin is a new quinolone with an antibacterial efficacy against methicillin-resistant Staphylococcus aureus (MRSA). Certain sequence types (STs) have been emerging in Taiwan, including fluoroquinolone-re...
Assessment of typing methods, virulence genes profile and antimicrobial susceptibility for clinical isolates of Proteus mirabilis [0.03%]
普罗威登菌的分型、毒力基因和临床分离株耐药性分析
Lamiaa A Salama,Hazem Hamed Saleh,Shaymaa H Abdel-Rhman et al.
Lamiaa A Salama et al.
Proteus mirabilis (P. mirabilis) is one of the most important causative pathogens associated with complicated urinary tract infections with a 20% incidence. For epidemiological determinations, several phenotypic and molecular typing methods...
Early initiation of ceftaroline-based combination therapy for methicillin-resistant Staphylococcus aureus bacteremia [0.03%]
MRSA菌血症早期启动cefataroline联合治疗
Addison S Hicks,Mackenzie A Dolan,Megan D Shah et al.
Addison S Hicks et al.
Purpose: Monotherapy with vancomycin or daptomycin remains guideline-based care for methicillin-resistant Staphylococcus aureus bacteremia (MRSA-B) despite concerns regarding efficacy. Limited data support potential benef...
Understanding the clinical and molecular epidemiological characteristics of carbapenem-resistant Acinetobacter baumannii infections within intensive care units of three teaching hospitals [0.03%]
上海市三甲医院重症监护室中碳青霉烯耐药的鲍曼不动杆菌感染的临床和分子流行病学特征分析
Pengyu Zhang,Jingchen Hao,Yafen Zhang et al.
Pengyu Zhang et al.
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is recognized as a common clinical conditional pathogen with blaOXA-23 gene-mediated multidrug-resistance that is a significant threat to public health safet...
Prevalence and molecular characteristics of colistin-resistant isolates among carbapenem-resistant Klebsiella pneumoniae in Central South China: a multicenter study [0.03%]
中国中南地区碳青霉烯耐药肺炎克雷伯菌中山.tolist耐药表型及分子特征流行状况：一项多中心研究
Zijuan Jian,Yanjun Liu,Zhiqian Wang et al.
Zijuan Jian et al.
Background: The emergence of colistin resistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) is a significant public health concern, as colistin has been the last resort for treating such infections. This study a...