Correction: Silencing Uracil-DNA glycosylase inhibits colorectal cancer progression [0.03%]
订正:沉默尿嘧啶-DNA糖基化酶可抑制结直肠癌的发展
Jing-Jing Yang,Li-Zhou Shi,Yong-Wei Hu et al.
Jing-Jing Yang et al.
Published Erratum
Cancer cell international. 2026 Jun 9;26(1):217. DOI:10.1186/s12935-026-04342-y 2026
Exosomes liquid biopsy in Lymphoma precision medicine: applications and challenges [0.03%]
外泌体液体活检在淋巴瘤精准医疗中的应用和挑战
Junxi Liu,Yu Peng,Yakun Zhang et al.
Junxi Liu et al.
Liquid biopsy is an emerging non-invasive detection technology that diagnoses tumors and provides prognostic value by analyzing samples such as circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and exosomes. Exosomes are nanosc...
An herbal formula, SH003 alleviates colorectal cancer through dual targeting of adaptive and innate checkpoints PD-L1/CD47 [0.03%]
一种草药配方SH003通过同时靶向适应性检查点PD-L1和先天性检查点CD47来缓解结直肠癌
Na-Ra Han,Hyun-Ha Hwang,Tae-Hyoun Kim et al.
Na-Ra Han et al.
Background: Colorectal cancer (CRC) is the third most common cancer. The use of immunotherapy for cancer has become widespread in recent decades and adaptive and innate checkpoints can be simultaneously targeted for enhan...
Multi-dimensional profiling of lactylation-related signatures for prognostic and therapeutic insights in bladder cancer [0.03%]
膀胱癌乳酰化相关特征的多维度谱型分析及其预后和诊疗价值
Hongjun Zhao,Kangjing Li,Hexin Xu et al.
Hongjun Zhao et al.
Background: Bladder cancer (BCa) is a prevalent malignancy with challenging prognosis and management. Lactylation, a novel post-translational modification, is dysregulated in various cancers. This study investigates lacty...
Clinical application of cytokine-induced killer cells in cancer immunotherapy [0.03%]
细胞因子诱导的杀伤细胞在肿瘤免疫治疗中的临床应用
Farzaneh Ghorbani,Hossein Abbaszadeh,Yahya Yahyavi et al.
Farzaneh Ghorbani et al.
Cytokine-induced killer (CIK) cells exhibit potent antitumor activity with reduced dependence on strict MHC compatibility, mediated by a combination of T-cell receptor (TCR)-dependent recognition and natural killer (NK)-like, MHC-unrestrict...
Modulation of splicing factors SF3B1 and SRSF1 by polypurine reverse Hoogsteen hairpins affects the splicing pattern of estrogen receptor α in breast cancer cells [0.03%]
多聚嘌呤反向Hoogsteen发夹通过调节乳腺癌细胞中的剪接因子SF3B1和SRSF1影响雌激素受体α的剪接模式
Ester López-Aguilar,Judith Cullell,Ana Delgado et al.
Ester López-Aguilar et al.
Multiple mRNA splice variants for the human estrogen receptor α (ERα) with one or more skipped exons have been identified, and some encode isoforms with modified functions compared with the wild-type 66 kDa protein. Our aim was to evaluat...
Celastrol induces apoptosis of myelodysplastic syndrome cells through a ROS-dependent pro-apoptotic endoplasmic-reticulum stress pathway [0.03%]
celastrol通过ROS依赖性促凋亡的内质网应激途径诱导骨髓增生异常综合征细胞发生凋亡
Fuxiang Zheng,Wenjun Shao,Li Liu et al.
Fuxiang Zheng et al.
Background: Myelodysplastic syndromes (MDS) represent clonal hematopoietic stem cell disorders with inherent propensity for leukemic transformation. Emerging evidence implicates dysregulated Endoplasmic-Reticulum stress (...
The anti-leukemic effects of vitamin K4 by modulating the JAK/STAT signaling pathway [0.03%]
维生素K4通过调节JAK/STAT信号传导途径产生抗白血病作用
Xiuyu Li,Pengcheng Zhu,Shaowen Hu et al.
Xiuyu Li et al.
Background: Vitamin K4 (VK4) is a hemostasis medicine used in clinical practice. It has also been reported to possess anti-cancer properties in types of solid tumors, however, its antitumor effects in leukemia cells are u...
DNA damage response signature-based prognostic genes for intrahepatic cholangiocarcinoma: a combined analysis of machine learning and biological experiments [0.03%]
基于DNA损伤反应特征的肝内胆管癌预后基因:机器学习与生物实验结合分析发现预测指标
Kai Lu,Hanqi Li,Yinying Wu et al.
Kai Lu et al.
Background: Intrahepatic cholangiocarcinoma (ICC) is a highly aggressive subtype of primary liver cancer with insidious onset, early metastasis, and poor prognosis. DNA damage response (DDR) dysfunction is linked to ICC t...
ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma [0.03%]
ADH4缺乏通过增加肝细胞癌中的脂质过氧化激活NRF2-CSF1轴
Ping Yan,Yunhai Luo,Dadi Peng et al.
Ping Yan et al.
Background: Hepatocellular carcinoma (HCC) is frequently associated with serious metabolic disorders, resulting in a bleak prognosis. Although ADH4 is implicated in the metabolism of fatty acids, its exact function in tum...