Stabilization of 5-aminolevulinic acid by cucurbit[7]uril complex with enhanced fluorescence detection and photodynamic therapy of breast cancer in vitro and in a CAM model [0.03%]
大环主体CB[7]包合物增强5-氨基乙基乳清酸光动力治疗体外及CAM乳腺癌模型中的荧光检测与稳定性研究
Sofía Pérez Del Pino,Walther Brown,Daniel Guerra Díaz et al.
Sofía Pérez Del Pino et al.
The FDA-approved prodrug 5-aminolevulinic acid (ALA) is efficiently metabolized by cancer cells into protoporphyrin IX (PpIX), a potent photosensitizer widely used in photodynamic therapy (PDT) and fluorescence-guided tumor surgery. However...
Targeted photodynamic therapy for MCF-7 breast cancer using antibody-conjugated, green-synthesized gold nanoparticles loaded with hypericin: a proof of concept [0.03%]
载圣约翰草素的抗体修饰金纳米粒子用于MCF-7乳腺癌肿瘤的光动力治疗：概念验证性研究
Mpho Mohlongo,Blassan P George,Heidi Abrahamse
Mpho Mohlongo
The treatment of breast cancer remains a significant clinical challenge, with limited responsiveness to conventional therapies. Photodynamic therapy, using the natural photosensitizer Hypericin, offers a promising modality, but its efficacy...
Comparative insights into single stranded RNAs interaction with methylene blue and new methylene blue: a photophysical, thermodynamic and modeling study [0.03%]
单链RNA与甲基蓝和新甲基蓝相互作用的比较见解：光物理、热力学及模型研究
Soumya Sundar Mati,Puja Paul
Soumya Sundar Mati
Studies on RNA and RNA-targeting inhibitors that regulate its expression form a central foundation of contemporary medicinal chemistry research. A combination of experimental methods that is spectroscopy and calorimetry and computational st...
Seasonal fluctuations of cardiovascular risk markers in patients referred to coronary angiography [0.03%]
冠状动脉造影受检者的血清心血管风险标记的季节性变化
Uwe Riedmann,Verena Theiler-Schwetz,Lisa Schmitt et al.
Uwe Riedmann et al.
Seasonal variation in cardiovascular disease (CVD) is well documented. Data on seasonal fluctuations in cardiovascular risk markers are relatively sparse but may be relevant for CVD risk classification and treatment. We aimed to quantify th...
Prue H Hart,Stephanie Trend,Allan G Kermode et al.
Prue H Hart et al.
There is a greater prevalence of multiple sclerosis (MS), a neurological autoimmune condition, in populations living further from the equator, hypothesised to be due to reduced sunlight exposure. There exists a proven sunlight surrogate the...
Direct photolysis of tiapride in water: deep insights into desulfonation reaction [0.03%]
水溶液中蒂阿普西的直接光解及其脱磺酸反应机理研究
Silvia Bertolotti,Diagne Mamadou,Guillaume Voyard et al.
Silvia Bertolotti et al.
The use of antipsychotics is constantly increasing worldwide due to their employment in the treatment of bipolar disorder, schizophrenia, autism, depression and more. These compounds are not efficiently removed by the current wastewater tre...
Photochemical synergy in hybrid sunscreen gels: enhanced UV protection and photostability with algal antioxidants, quercetin, azobenzene, and chitosan-coated TiO₂ nanoparticles [0.03%]
含海藻抗氧化物、槲皮素、azarbenzene和壳聚糖涂覆的二氧化钛纳米粒子的混合防晒凝胶中的光化学协同作用：增强UV防护及光稳定性
Mohammad Abu Shuheil,Munthar Kadhim Abosaoda,M M Rekha et al.
Mohammad Abu Shuheil et al.
This study presents a photochemically optimized hybrid sunscreen gel integrating natural algal extracts (Spirulina platensis and Chlorella vulgaris), quercetin, azobenzene, and chitosan-coated titanium dioxide (TiO₂) nanoparticles to achie...
The cutaneous microbiome as a dynamic photoprotective interface against solar radiation [0.03%]
皮肤微生物组作为抵御太阳辐射的动态光防护界面
Jeremy R Ellis,Eron J Powell,Luke M Tomasovic et al.
Jeremy R Ellis et al.
Light-induced oxidative dehydrogenation of 12,13-dihydro-5H-indolo[3,2-c]acridine [0.03%]
光诱导的12,13-二氢-5H-吲哚并[3,2-]乙撑亚胺的氧化脱氢反应
Barbara Golec,Michał Kijak,Krzysztof Nawara et al.
Barbara Golec et al.
Photochemical dehydrogenation of the 1,3-cyclohexadiene-type ring of 12,13-dihydro-5H-indolo[3,2-c]acridine (1) by singlet oxygen was observed in n-hexane, acetonitrile and methanol. UV irradiation of 1 leads exclusively to the formation of...
Photochemical transformation of paracetamol sensitized by humic acid: pH-dependent pathways and mechanisms [0.03%]
腐殖酸敏化 para-氨基酚的光化学转化：pH依赖性路径和机制
Alberto Barrera,José Natera,Eduardo Gatica et al.
Alberto Barrera et al.