Antimicrobial photodynamic therapy reprograms resistance by inducing sensitization in methicillin-resistant Staphylococcus aureus [0.03%]
光动力疗法通过诱导甲氧西林耐药金黄色葡萄球菌敏感到耐药重编程
Jennifer M Soares,Carla Calçada,Vladislav V Yakovlev et al.
Jennifer M Soares et al.
Combination therapies are a crucial strategy to decelerate the progression of antimicrobial resistance in microorganisms. In this context, antimicrobial photodynamic therapy (aPDT) emerges as a valuable adjuvant, not only for infection erad...
Quantum chemistry study on the feasibility of triplet-triplet energy transfer in the dark photosensitization of DNA [0.03%]
关于暗态光敏化过程中三重态-三重态能量转移可行性的量子化学研究
María Ortuño-Martínez,Juliana Cuéllar-Zuquin,Daniel Roca-Sanjuán
María Ortuño-Martínez
Cyclobutane pyrimidine dimers (CPDs) are classically formed in DNA upon ultraviolet (UV) irradiation; however, recent evidences demonstrate that CPDs can also arise in the dark. This mechanism involves the formation of dioxetanes from react...
Mechanistic insights into evolution of bioluminescence from luciferyl-adenylate chemiluminescence [0.03%]
从化学发光到荧光素酰腺苷生物发光的机制洞察
Vadim R Viviani,Kazuki Niwa,Yoshihiro Nakajima et al.
Vadim R Viviani et al.
Luciferyl-adenylate (LH2AMP) is the key chemiluminescent intermediate in the bioluminescence reaction catalyzed by beetle luciferases. Whereas the luciferase-catalyzed bioluminescence reactions usually proceed with high quantum yields in th...
Solvent polarity and chalcogen electronegativity synergistically regulate excited-state proton transfer in BBYPD derivatives [0.03%]
溶剂极性和硫属元素亲电性协同调节BBYPD衍生物的激发态质子转移反应
Han Wang,Jinfeng Zhao,Wei Hua et al.
Han Wang et al.
This study aims to investigate the regulatory behaviors of solvent polarity and chalcogen electronegativity on excited-state proton transfer process of BBYPD derivatives, filling the theoretical gaps related to proton transfer pathways and ...
State of darkness protection in strategic lighting documents of 10 European cities [0.03%]
欧洲十个城市战略照明文件中的黑暗保护状况
Riikka Vuorenmaa,Henrika Pihlajaniemi,Outi Parhankangas
Riikka Vuorenmaa
Minimizing the adverse effects of lighting and enabling safe and justified darkness are prerequisites for sustainable urban lighting. In this paper, we analyse the justifications and measures that 10 European cities have documented for prot...
Porphyrin dendrimers as effective dye bleaching sensitizers in high water content solutions [0.03%]
高含水量溶液中的卟啉树枝状分子作为有效的染料漂白敏化剂
Julián A Salas Pájaro,María J Gramaglia,Micaela E Grassano et al.
Julián A Salas Pájaro et al.
In this work, a comparative analysis on dye bleaching capacity of porphyrin-core dendrimers (Pf-Ds) of two different sizes (first and second generations) in high water content media is carried out. First, a series of new second-generation c...
A long-wavelength tetraphenylethylene-derived fluorescent probe for sensitive detection of heparin and protamine [0.03%]
一种检测肝素和protamine的长波长四苯乙烯衍生物荧光探针
Yutian Jiao,Gongli Wei,Ying Feng et al.
Yutian Jiao et al.
Heparin and protamine are vital biomacromolecules extensively used in clinical settings, necessitating precise monitoring of their concentrations. In this study, a novel positively charged fluorescent probe was developed, derived from an ag...
Modulating the amphiphilic character of porphyrins with pH-activatable cationic centers and fluorocarbon chains to enhance antimicrobial photodynamic activity against Candida albicans [0.03%]
通过pH激活的阳离子中心和氟碳链调节卟啉两亲性以增强抗白色念珠菌光动力活性
Yohana B Palacios,Edwin J Gonzalez Lopez,Sofia C Santamarina et al.
Yohana B Palacios et al.
The rise of antifungal-resistant yeast and the increasing prevalence of invasive mycoses, particularly those caused by Candida albicans, pose a significant global public health challenge. This is primarily due to the limited availability of...
Antimicrobial photodynamic therapy using tetra-cationic porphyrins with peripheral platinum(II) and palladium(II) complexes against multidrug-resistant bacteria isolated from canine otitis [0.03%]
用于治疗从犬中耳炎分离出的耐多药细菌的四阳离子型铂(II)/钯(II)配合物外周修饰卟啉光动力疗法
Tauana Fernanda Jantsch Voigt,Eduarda Martins,Vivian Franklin da Silva et al.
Tauana Fernanda Jantsch Voigt et al.
This study aimed to evaluate the cytotoxicity and photodynamic antimicrobial activity of tetra-cationic porphyrins containing peripheral platinum(II) (3-PtTPyP and 4-PtTPyP) and palladium(II) (3-PdTPyP and 4-PdTPyP) complexes against multid...
To distinguish solarium use with and without risk behavior on melanoma incidence and all-cause mortality: a report from the large MISS cohort [0.03%]
一项来自大型MISS队列的报告：区分日光浴床使用（有无冒险行为）对黑色素瘤发病率和全因死亡率的影响
Pelle G Lindqvist,Elliot L Epstein,Mona Landin-Olsson
Pelle G Lindqvist
Background: Artificial ultraviolet radiation (UVR) from solarium use has been linked to melanoma in some studies, while others report lower overall mortality. Whether melanoma risk is due to solarium use itself or to asso...