Publisher Correction: Modeling group heteroscedasticity in single-cell RNA-seq pseudo-bulk data [0.03%]
出版更正：单细胞RNA测序假批量数据中 modelling group heteroscedasticity 的建模
Yue You,Xueyi Dong,Yong Kiat Wee et al.
Yue You et al.
Published Erratum
Genome biology. 2023 May 12;24(1):112. DOI:10.1186/s13059-023-02965-2 2023
Cross-phyla protein annotation by structural prediction and alignment [0.03%]
基于结构预测和序列比对的多门类蛋白质注释方法
Fabian Ruperti,Nikolaos Papadopoulos,Jacob M Musser et al.
Fabian Ruperti et al.
Background: Protein annotation is a major goal in molecular biology, yet experimentally determined knowledge is typically limited to a few model organisms. In non-model species, the sequence-based prediction of gene ortho...
Tamsin E M Jones,Bethan Yates,Bryony Braschi et al.
Tamsin E M Jones et al.
The Vertebrate Gene Nomenclature Committee (VGNC) was established in 2016 as a sister project to the HUGO Gene Nomenclature Committee, to approve gene nomenclature in vertebrate species without an existing dedicated nomenclature committee. ...
Genetic basis of geographical differentiation and breeding selection for wheat plant architecture traits [0.03%]
小麦株型地理分化及育种选择的遗传基础
Yangyang Liu,Kuocheng Shen,Changbin Yin et al.
Yangyang Liu et al.
Background: Plant architecture associated with increased grain yield and adaptation to the local environments is selected during wheat (Triticum aestivum) breeding. The internode length of individual stems and tiller leng...
Decoding enhancer complexity with machine learning and high-throughput discovery [0.03%]
运用机器学习和高通量鉴定解析增强子的复杂性
Gabrielle D Smith,Wan Hern Ching,Paola Cornejo-Páramo et al.
Gabrielle D Smith et al.
Enhancers are genomic DNA elements controlling spatiotemporal gene expression. Their flexible organization and functional redundancies make deciphering their sequence-function relationships challenging. This article provides an overview of ...
Genome-wide association analysis reveals a novel pathway mediated by a dual-TIR domain protein for pathogen resistance in cotton [0.03%]
全基因组关联分析揭示了棉花中由双TIR结构域蛋白介导的新的抗病通路
Yihao Zhang,Yaning Zhang,Xiaoyang Ge et al.
Yihao Zhang et al.
Background: Verticillium wilt is one of the most devasting diseases for many plants, leading to global economic loss. Cotton is known to be vulnerable to its fungal pathogen, Verticillium dahliae, yet the related genetic ...
High-throughput deep learning variant effect prediction with Sequence UNET [0.03%]
基于Sequence UNET的高通量深度学习变异效应预测
Alistair S Dunham,Pedro Beltrao,Mohammed AlQuraishi
Alistair S Dunham
Understanding coding mutations is important for many applications in biology and medicine but the vast mutation space makes comprehensive experimental characterisation impossible. Current predictors are often computationally intensive and d...
Correcting gradient-based interpretations of deep neural networks for genomics [0.03%]
用于基因组学的深度神经网络的梯度解释的纠正方法
Antonio Majdandzic,Chandana Rajesh,Peter K Koo
Antonio Majdandzic
Post hoc attribution methods can provide insights into the learned patterns from deep neural networks (DNNs) trained on high-throughput functional genomics data. However, in practice, their resultant attribution maps can be challenging to i...
Hybrid allele-specific ChIP-seq analysis identifies variation in brassinosteroid-responsive transcription factor binding linked to traits in maize [0.03%]
杂交特异性染色质免疫沉淀测序分析鉴定出与玉米性状相关的 brassinosteroid 响应型转录因子结合位点变异
Thomas Hartwig,Michael Banf,Gisele Passaia Prietsch et al.
Thomas Hartwig et al.
Background: Genetic variation in regulatory sequences that alter transcription factor (TF) binding is a major cause of phenotypic diversity. Brassinosteroid is a growth hormone that has major effects on plant phenotypes. ...
DDM1-mediated gene body DNA methylation is associated with inducible activation of defense-related genes in Arabidopsis [0.03%]
拟南芥中DDM1介导的基因体DNA甲基化与防卫相关诱导基因激活有关
Seungchul Lee,Jaemyung Choi,Jihwan Park et al.
Seungchul Lee et al.
Background: Plants memorize previous pathogen attacks and are "primed" to produce a faster and stronger defense response, which is critical for defense against pathogens. In plants, cytosines in transposons and gene bodie...