Cross-species prediction of histone modifications in plants via deep learning [0.03%]
基于深度学习的植物组蛋白修饰跨物种预测
Tongxuan Lv,Quan Han,Yilin Li et al.
Tongxuan Lv et al.
Background: The regulation of gene expression in plants is governed by complex interactions between cis-regulatory elements and epigenetic modifications such as histone marks. While deep learning models have achieved succ...
Shiron Drusinsky,Sean Whalen,Katherine S Pollard
Shiron Drusinsky
Background: Models that predict gene expression levels from DNA sequence struggle to predict differences between individuals when given their personal genome sequences. These models are generally trained on reference geno...
Abhishek Gogna,Bahareh Kamali,Valentin Wimmer et al.
Abhishek Gogna et al.
Background: Breeding programs prioritize the average performance of a genotype across environments and may overlook promising candidates for specific environments. To address this challenge, we propose a genomic predictio...
Yicheng Huang,Enlai Guan,Shipeng Song et al.
Yicheng Huang et al.
Background: Centromere function is fundamental and conserved across eukaryotes, despite highly divergent DNA sequences, even among closely related species. These regions often contain rapidly evolving repeats and retrotra...
Core microbiota recruited by healthy grapevines enhance resistance against root rot disease [0.03%]
健康葡萄藤的核心微生物群可增强抵抗根腐病的能力
Ruotong Wang,Wenyu Zhang,Zhishan He et al.
Ruotong Wang et al.
Background: Root rot disease caused by fungal pathogens of wine grapevines poses a serious threat to their growth and results in a substantial economic impact on grape industry. The rhizosphere microbiome recruited to pla...
Tessa R MacNish,Thomas Bergmann,David Edwards
Tessa R MacNish
There is an urgent need to increase sustainable crop production. The application of molecular marker technologies such as genomic selection and machine learning based approaches are aiding accelerated crop improvement. Conventional molecula...
Global atlas of enhancer-promoter interactome in cotton genome revealed by profiling RNA-RNA spatial interactions [0.03%]
棉花基因组中调控元件与转录起始位点互作的全局图谱——通过表征RNA-RNA空间构象解析棉属物种组织发育和驯化的遗传基础
Miaomiao Wen,Xiaodong Liang,Keke Shi et al.
Miaomiao Wen et al.
Background: RNA-RNA spatial interactions play crucial roles in various cellular processes, including gene transcriptional and post-transcriptional regulations. However, research on this area of RNA regulation remains limi...
Unravelling the progression of the zebrafish primary body axis with reconstructed spatiotemporal transcriptomics [0.03%]
具有时空转录组学的重建斑马鱼主轴进展解析
Yang Dong,Tao Cheng,Xiang Liu et al.
Yang Dong et al.
Background: Elucidating the spatiotemporal dynamics of gene expression is essential for understanding complex physiological and pathological processes. Current spatial transcriptomics techniques are hindered by low read d...
The repetitive genome of the Ixodes ricinus tick reveals transposable elements have driven genome evolution in ticks [0.03%]
Ixodes ricinus的重复基因组表明转座元件驱动了全基因组的进化
Isobel Ronai,Rodrigo de Paula Baptista,Nicole S Paulat et al.
Isobel Ronai et al.
Background: Ticks are obligate blood-feeding parasites associated with a huge diversity of diseases globally. The hard tick Ixodes ricinus is the key vector of Lyme borreliosis and tick-borne encephalitis in Western Euras...
Coordinated single-nucleus responses for quantitative disease resistance involve a calcium-associated switch in transcriptional noise [0.03%]
定量抗病性涉及钙相关的转录噪声开关的协调单核响应
Darcy A B Jones,Florent Delplace,Mehdi Khafif et al.
Darcy A B Jones et al.
Background: Efficient plant immune response requires concerted reprogramming of cellular transcriptomes both globally and locally at the site of infection. Upon inoculation by the fungal pathogen Sclerotinia sclerotiorum,...