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期刊名:Genome biology

缩写:GENOME BIOL

ISSN:1474-760X

e-ISSN:1474-760X

IF/分区:9.4/Q1

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共收录本刊相关文章索引6360
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Ke Cao,Bin Wang,Weichao Fang et al. Ke Cao et al.
Background: Plant metabolites reshaped by nature and human beings are crucial for both their lives and human health. However, which metabolites respond most strongly to selection pressure at different evolutionary stages ...
Ya-Mei Ding,Yu Cao,Wei-Ping Zhang et al. Ya-Mei Ding et al.
Background: Persian walnut, Juglans regia, occurs naturally from Greece to western China, while its closest relative, the iron walnut, Juglans sigillata, is endemic in southwest China; both species are cultivated for thei...
Yifan Zhang,Thomas M Blomquist,Rebecca Kusko et al. Yifan Zhang et al.
Background: Clinical laboratories routinely use formalin-fixed paraffin-embedded (FFPE) tissue or cell block cytology samples in oncology panel sequencing to identify mutations that can predict patient response to targete...
Eiru Kim,Lance C Novak,Chenchu Lin et al. Eiru Kim et al.
Background: Coessentiality networks derived from CRISPR screens in cell lines provide a powerful framework for identifying functional modules in the cell and for inferring the roles of uncharacterized genes. However, thes...
Michael A Schon,Stefan Lutzmayer,Falko Hofmann et al. Michael A Schon et al.
We developed Bookend, a package for transcript assembly that incorporates data from different RNA-seq techniques, with a focus on identifying and utilizing RNA 5' and 3' ends. We demonstrate that correct identification of transcript start a...
Gamze Gürsoy,Charlotte M Brannon,Eric Ni et al. Gamze Gürsoy et al.
There are major efforts underway to make genome sequencing a routine part of clinical practice. A critical barrier to these is achieving practical solutions for data ownership and integrity. Blockchain provides solutions to these challenges...
Ziqi Zhang,Chengkai Yang,Xiuwei Zhang Ziqi Zhang
It is a challenging task to integrate scRNA-seq and scATAC-seq data obtained from different batches. Existing methods tend to use a pre-defined gene activity matrix to convert the scATAC-seq data into scRNA-seq data. The pre-defined gene ac...
Hanbin Lee,Buhm Han Hanbin Lee
Most genomic cohorts are retrospective where the exposures and outcomes are predetermined prior to sample collection. Therefore, a spurious association between an exposure and an outcome can arise if both variables affect study participatio...
Jake Crawford,Brock C Christensen,Maria Chikina et al. Jake Crawford et al.
Background: In studies of cellular function in cancer, researchers are increasingly able to choose from many -omics assays as functional readouts. Choosing the correct readout for a given study can be difficult, and which...