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期刊名:Genome biology

缩写:GENOME BIOL

ISSN:1474-760X

e-ISSN:1474-760X

IF/分区:9.4/Q1

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共收录本刊相关文章索引6360
Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Xiaoqi Liang,Marni Torkel,Yue Cao et al. Xiaoqi Liang et al.
Background: Computational methods for spatially resolved transcriptomics (SRT) are often developed and assessed using simulated data. The effectiveness of these evaluations relies on the ability of simulation methods to a...
Rong Liu,Chaoqin Hu,Dan Gao et al. Rong Liu et al.
Background: A comprehensive study of the genome and genetics of superior germplasms is fundamental for crop improvement. As a widely adapted protein crop with high yield potential, the improvement in breeding and developm...
Haihuan Shan,Shuangshuang Fan,Quanrun Li et al. Haihuan Shan et al.
Background: Dyslipidemia or hypercholesterolemia are among the main risk factors for cardiovascular diseases. Unraveling the molecular basis of lipid or cholesterol homeostasis would help to identify novel drug targets an...
Yered Pita-Juarez,Dimitra Karagkouni,Nikolaos Kalavros et al. Yered Pita-Juarez et al.
Background: The molecular underpinnings of organ dysfunction in severe COVID-19 and its potential long-term sequelae are under intense investigation. To shed light on these in the context of liver function, we perform sin...
Hui Feng,Yufei Li,Guoxin Dai et al. Hui Feng et al.
Background: Metabolomics is one of the most widely used omics tools for deciphering the functional networks of the metabolites for crop improvement. However, it is technically demanding and costly. ...
Yuna Yang,Yuqing Huang,Tian Wang et al. Yuna Yang et al.
Background: N6-methyladenosine (m6A) is a prevalent and conserved RNA modification in eukaryotes. While its roles in the 3' untranslated regions (3' UTR) are well-studied, its role in the 5' UTR and its relationship with ...
Mingyao Wang,Pengchong Fu,Ziheng Chen et al. Mingyao Wang et al.
Chromosomal rearrangements, such as translocations, deletions, and inversions, underlie numerous genetic diseases and cancers, yet precise engineering of these rearrangements remains challenging. Here, we present a CRISPR-based homologous r...
Yang Qiu,Lifen Liu,Jiali Yan et al. Yang Qiu et al.
Background: Identifying transcriptional cis-regulatory elements (CREs) and understanding their role in gene expression are essential for the precise manipulation of gene expression and associated phenotypes. This knowledg...
Robert Chen,Ben Omega Petrazzini,Áine Duffy et al. Robert Chen et al.
Background: Genome-wide association studies (GWAS) have identified common variants associated with metabolic dysfunction-associated steatotic liver disease (MASLD). However, rare coding variant studies have been limited b...