Publisher Correction: The haplotype-resolved genome assembly of an ancient citrus variety provides insights into the domestication history and fruit trait formation of loose-skin mandarins [0.03%]
古柑橘品种的单倍型解析基因组组装为了解松皮柑橘的驯化历史和果实性状形成提供了见解:出版更正
Minqiang Yin,Xiaochan Song,Chao He et al.
Minqiang Yin et al.
Published Erratum
Genome biology. 2025 Mar 28;26(1):78. DOI:10.1186/s13059-025-03551-4 2025
Benchmarking spatial transcriptomics technologies with the multi-sample SpatialBenchVisium dataset [0.03%]
使用多样本SpatialBenchVisium数据集评估空间转录组学技术
Mei R M Du,Changqing Wang,Charity W Law et al.
Mei R M Du et al.
Background: Spatial transcriptomics allows gene expression to be measured within complex tissue contexts. Among the array of spatial capture technologies available is 10x Genomics' Visium platform, a popular method which ...
Pamoic acid and carbenoxolone specifically inhibit CRISPR/Cas9 in bacteria, mammalian cells, and mice in a DNA topology-specific manner [0.03%]
帕莫酸和卡贝胆碱以DNA拓扑结构特异性方式特异抑制细菌、哺乳动物细胞和小鼠中的CRISPR / Cas9系统
Yuxuan Zhang,Wentao Zou,Yueyang Zhou et al.
Yuxuan Zhang et al.
Background: Regulation of the target DNA cleavage activity of CRISPR/Cas has naturally evolved in a few bacteria or bacteriophages but is lacking in higher species. Thus, identification of bioactive agents and mechanisms ...
MACAW: a method for semi-automatic detection of errors in genome-scale metabolic models [0.03%]
MACAW:一种用于基因组规模代谢模型中半自动检测误差的方法
Devlin C Moyer,Justin Reimertz,Daniel Segrè et al.
Devlin C Moyer et al.
Genome-scale metabolic models (GSMMs) are used to predict metabolic fluxes, with applications ranging from identifying novel drug targets to engineering microbial metabolism. Erroneous or missing reactions, scattered throughout densely inte...
DEMINERS enables clinical metagenomics and comparative transcriptomic analysis by increasing throughput and accuracy of nanopore direct RNA sequencing [0.03%]
DEMINERS通过提高纳米孔直接RNA测序的吞吐量和准确性,使临床元转录组学和比较转录组学分析成为可能
Junwei Song,Li-An Lin,Chao Tang et al.
Junwei Song et al.
Nanopore direct RNA sequencing (DRS) is a powerful tool for RNA biology but suffers from low basecalling accuracy, low throughput, and high input requirements. We present DEMINERS, a novel DRS toolkit combining an RNA multiplexing workflow,...
Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells [0.03%]
作者更正:结合不同的CRISPR核酸酶进行同时敲入和基础编辑可防止多重编辑CAR T细胞中的易位
Viktor Glaser,Christian Flugel,Jonas Kath et al.
Viktor Glaser et al.
Published Erratum
Genome biology. 2025 Mar 26;26(1):71. DOI:10.1186/s13059-025-03548-z 2025
Regulatory and disruptive variants in the CLCN2 gene are associated with modified skin color pattern phenotypes in the corn snake [0.03%]
CLCN2基因中的调控变异和颠覆性变异与玉米蛇皮肤颜色图案表型的改变相关
Sophie A Montandon,Pierre Beaudier,Asier Ullate-Agote et al.
Sophie A Montandon et al.
Background: Snakes exhibit a broad variety of adaptive colors and color patterns, generated by the spatial arrangement of chromatophores, but little is known of the mechanisms responsible for these spectacular traits. Her...
LocusMasterTE: integrating long-read RNA sequencing improves locus-specific quantification of transposable element expression [0.03%]
LocusMasterTE:整合长读RNA序列以提高转座子表达的定位特异性定量准确性
Sojung Lee,Jayne A Barbour,Yee Man Tam et al.
Sojung Lee et al.
Transposable elements (TEs) can influence human diseases by disrupting genome integrity, yet their quantification has been challenging due to the repetitive nature of these sequences across the genome. We develop LocusMasterTE, a method tha...
Survey of gene, lncRNA and transposon transcription patterns in four mouse organs highlights shared and organ-specific sex-biased regulation [0.03%]
对小鼠四种器官中的基因、长非编码 RNA 和转座子的转录模式进行调研,强调共用和器官特异性性别偏向性调控
Qinwei Kim-Wee Zhuang,Klara Bauermeister,Jose Hector Galvez et al.
Qinwei Kim-Wee Zhuang et al.
Background: Sex-biased gene regulation is the basis of sexual dimorphism in phenotypes and has been studied across different cell types and different developmental stages. However, sex-biased expression of transposable el...
Clonal expansion dictates the efficacy of mitochondrial lineage tracing in single cells [0.03%]
克隆扩增决定线粒体谱系追踪在单细胞中的效果
Xin Wang,Kun Wang,Weixing Zhang et al.
Xin Wang et al.
Background: Mitochondrial DNA (mtDNA) variants hold promise as endogenous barcodes for tracking human cell lineages, but their efficacy as reliable lineage markers are hindered by the complex dynamics of mtDNA in somatic ...