Leptospirosis deaths in children in the Amazon: syndemic inequities [0.03%]
亚马逊地区的儿童钩端螺旋体病死亡：流行病学不平等
Esteban Ortiz-Prado,Juan S Izquierdo-Condoy,Camila Salazar-Santoliva et al.
Esteban Ortiz-Prado et al.
Oriol Mitjà,Deborah Watson-Jones,Edward M Choi et al.
Oriol Mitjà et al.
GLP-1 and amylin receptor multiagonism with amycretin for obesity management [0.03%]
用于肥胖管理的胰高血糖素样肽-1和淀粉肽受体多激动效应
Bernard Khoo,Tricia M-M Tan
Bernard Khoo
Amycretin, a novel, unimolecular GLP-1 and amylin receptor agonist administered subcutaneously: results from a phase 1b/2a randomised controlled study [0.03%]
一种新型的、单分子的葡萄糖依赖性促胰岛素多肽和人AMYLIN受体激动剂皮下注射：一项1b/2a期随机对照研究结果
Kirsten Dahl,Søren Toubro,Sohan Dey et al.
Kirsten Dahl et al.
Background: Amycretin is a novel, unimolecular GLP-1 and amylin receptor agonist. The aim of this study was to investigate the safety, tolerability, pharmacokinetics, and effects on bodyweight of subcutaneous amycretin ad...
Cerebral palsy [0.03%]
脑性麻痹
Iona Novak,Michelle Jackman,Megan Finch-Edmondson et al.
Iona Novak et al.
Cerebral palsy is a lifelong physical disability affecting movement and posture. The motor impairments of cerebral palsy result from non-degenerative brain injuries, brain malformations, and genetic variations, arising from multiple risk fa...
Safety, tolerability, pharmacokinetics, and pharmacodynamics of the first-in-class GLP-1 and amylin receptor agonist, amycretin: a first-in-human, phase 1, double-blind, randomised, placebo-controlled trial [0.03%]
靶向GLP-1和胰淀素受体激动剂（AMYCRETIN）首次人体试验：一项随机、双盲、安慰剂对照I期临床研究
Agnes Gasiorek,Arne Heydorn,Sanaz Gabery et al.
Agnes Gasiorek et al.
Background: GLP-1 receptor agonists and amylin receptor agonists have shown clinically relevant weight loss and glucose-lowering effects in people with overweight, obesity, and type 2 diabetes. Amycretin is a novel, singl...
Udani Samarasekera
Udani Samarasekera
Current treatment for symptomatic uterine fibroids: available evidence and therapeutic dilemmas [0.03%]
子宫肌瘤的当前治疗：现有证据与困境挑战
Noa S de Smit,Maria E de Lange,Martijn F Boomsma et al.
Noa S de Smit et al.
This Review offers an evaluation of current treatments for symptomatic uterine fibroids, including uterine artery embolisation, MRI-guided high-intensity focused ultrasound, laparoscopic radiofrequency ablation, transcervical radiofrequency...
Mitapivat in adults with non-transfusion-dependent α-thalassaemia or β-thalassaemia (ENERGIZE): a phase 3, international, randomised, double-blind, placebo-controlled trial [0.03%]
非 transfusion 密切相关的α-或β-地中海贫血成人患者中的mitapivat(ENERGIZE):一项随机双盲安慰剂对照3期国际试验
Ali T Taher,Hanny Al-Samkari,Yesim Aydinok et al.
Ali T Taher et al.
Background: Non-transfusion-dependent (NTD) thalassaemia is characterised by ineffective erythropoiesis and haemolytic anaemia, leading to long-term complications, poor quality of life, and early mortality. No oral diseas...
Selim Corbacioglu
Selim Corbacioglu